Imaging a functional tumorigenic biomarker in the transformed epithelium.
LeBeau, Aaron M; Lee, Minhee; Murphy, Stephanie T; Hann, Byron C; Warren, Robert S; Delos Santos, Romelyn; Kurhanewicz, John; Hanash, Samir M; VanBrocklin, Henry F; Craik, Charles S.
Proc Natl Acad Sci U S A
; 110(1): 93-8, 2013 Jan 02.
Artigo em Inglês | MEDLINE | ID: mdl-23248318
Crystal structures of matriptase in complex with its inhibitor hepatocyte growth factor activator inhibitor-1.
Phosphorylation of the type II transmembrane serine protease, TMPRSS13, in hepatocyte growth factor activator inhibitor-1 and -2-mediated cell-surface localization.
A phosphomimetic-based mechanism of dengue virus to antagonize innate immunity.
Cleavage of hepatocyte growth factor activator inhibitor-1 by membrane-type MMP-1 activates matriptase.
The protease inhibitor HAI-2, but not HAI-1, regulates matriptase activation and shedding through prostasin.
Serological Analysis of Immunogenic Properties of Recombinant Meningococcus IgA1 Protease-Based Proteins.
Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin.
Imbalanced matriptase pericellular proteolysis contributes to the pathogenesis of malignant B-cell lymphomas.
The crystal structure of a multidomain protease inhibitor (HAI-1) reveals the mechanism of its auto-inhibition.
Mechanisms for the control of matriptase activity in the absence of sufficient HAI-1.