Neutrophil cerebrovascular transmigration triggers rapid neurotoxicity through release of proteases associated with decondensed DNA.
Allen, Charlotte; Thornton, Peter; Denes, Adam; McColl, Barry W; Pierozynski, Adam; Monestier, Marc; Pinteaux, Emmanuel; Rothwell, Nancy J; Allan, Stuart M.
; 189(1): 381-92, 2012 Jul 01.
Artigo em Inglês | MEDLINE | ID: mdl-22661091
Interleukin-1 deficiency prolongs ovarian lifespan in mice.
Cutting edge: nitrogen bisphosphonate-induced inflammation is dependent upon mast cells and IL-1.
Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis.
IL-1α and IL-1ß recruit different myeloid cells and promote different stages of sterile inflammation.
Requirement for interleukin-1 to drive brain inflammation reveals tissue-specific mechanisms of innate immunity.
Identification of the cellular sensor that stimulates the inflammatory response to sterile cell death.
The role of macrophage-derived IL-1 in induction and maintenance of angiogenesis.
Glutathione reductase facilitates host defense by sustaining phagocytic oxidative burst and promoting the development of neutrophil extracellular traps.
IL-1-induced inflammation promotes development of leishmaniasis in susceptible BALB/c mice.
CD11b/CD18 (Mac-1) is a novel surface receptor for extracellular double-stranded RNA to mediate cellular inflammatory responses.