The life history of 21 breast cancers.
Nik-Zainal, Serena; Van Loo, Peter; Wedge, David C; Alexandrov, Ludmil B; Greenman, Christopher D; Lau, King Wai; Raine, Keiran; Jones, David; Marshall, John; Ramakrishna, Manasa; Shlien, Adam; Cooke, Susanna L; Hinton, Jonathan; Menzies, Andrew; Stebbings, Lucy A; Leroy, Catherine; Jia, Mingming; Rance, Richard; Mudie, Laura J; Gamble, Stephen J; Stephens, Philip J; McLaren, Stuart; Tarpey, Patrick S; Papaemmanuil, Elli; Davies, Helen R; Varela, Ignacio; McBride, David J; Bignell, Graham R; Leung, Kenric; Butler, Adam P; Teague, Jon W; Martin, Sancha; Jönsson, Goran; Mariani, Odette; Boyault, Sandrine; Miron, Penelope; Fatima, Aquila; Langerød, Anita; Aparicio, Samuel A J R; Tutt, Andrew; Sieuwerts, Anieta M; Borg, Åke; Thomas, Gilles; Salomon, Anne Vincent; Richardson, Andrea L; Børresen-Dale, Anne-Lise; Futreal, P Andrew; Stratton, Michael R; Campbell, Peter J.
; 149(5): 994-1007, 2012 May 25.
Artigo em Inglês | MEDLINE | ID: mdl-22608083
Multiclonal Invasion in Breast Tumors Identified by Topographic Single Cell Sequencing.
Clonal evolution in breast cancer revealed by single nucleus genome sequencing.
Cancer: One cell at a time.
The genomic landscape of metastasis in treatment-naïve breast cancer models.
Revealing clonality and subclonality of driver genes for clinical survival benefits in breast cancer.
Breast cancer intra-tumor heterogeneity.
The next generation personalized models to screen hidden layers of breast cancer tumorigenicity.
Consecutive seeding and transfer of genetic diversity in metastasis.
A primary breast cancer with distinct foci of estrogen receptor-alpha positive and negative cells derived from the same clonal origin as revealed by whole exome sequencing.
Clonal evolution driven by superdriver mutations.