Large-scale analysis of tumor necrosis factor α levels in systemic lupus erythematosus.
Weckerle, Corinna E; Mangale, Dorothy; Franek, Beverly S; Kelly, Jennifer A; Kumabe, Marissa; James, Judith A; Moser, Kathy L; Harley, John B; Niewold, Timothy B.
; 64(9): 2947-52, 2012 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-22488302
Network analysis of associations between serum interferon-α activity, autoantibodies, and clinical features in systemic lupus erythematosus.
Altered type II interferon precedes autoantibody accrual and elevated type I interferon activity prior to systemic lupus erythematosus classification.
Circulating interferon-α2 levels are increased in the majority of patients with systemic lupus erythematosus and are associated with disease activity and multiple cytokine activation.
Interferon alpha gene expression and serum level association with low vitamin D levels in Egyptian female patients with systemic lupus erythematosus.
Anti-ribosomal P antibodies are associated with elevated circulating IFNα and IL-10 levels in systemic lupus erythematosus patients.
Serum free light chains, interferon-alpha, and interleukins in systemic lupus erythematosus.
Gene-expression-guided selection of candidate loci and molecular phenotype analyses enhance genetic discovery in systemic lupus erythematosus.
Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-α and serologic autoimmunity in lupus patients.
Elevated plasma level of HMGB1 is associated with disease activity and combined alterations with IFN-α and TNF-α in systemic lupus erythematosus.
Interféron-alpha: une cytokine clé dans la physiopathologie du lupus systémique.