Development of a robust cytopathic effect-based high-throughput screening assay to identify novel inhibitors of dengue virus.
McCormick, Kevin D; Liu, Shufeng; Jacobs, Jana L; Marques, Ernesto T A; Sluis-Cremer, Nicolas; Wang, Tianyi.
Antimicrob Agents Chemother
; 56(6): 3399-401, 2012 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-22391547
High-Throughput Imaging for the Discovery of Cellular Mechanisms of Disease.
Deorphanization strategies for dark chemical matter.
High-throughput binding affinity calculations at extreme scales.
Novel dengue virus-specific NS2B/NS3 protease inhibitor, BP2109, discovered by a high-throughput screening assay.
Discovery of 2-oxopiperazine dengue inhibitors by scaffold morphing of a phenotypic high-throughput screening hit.
A microfabricated 96-well wound-healing assay.
Rank ordering plate data facilitates data visualization and normalization in high-throughput screening.
Suramin inhibits helicase activity of NS3 protein of dengue virus in a fluorescence-based high throughput assay format.
A high throughput screening system of coils for ELF magnetic fields experiments: proof of concept on the proliferation of cancer cell lines.
Proteome signatures--how are they obtained and what do they teach us?