PGV04, an HIV-1 gp120 CD4 binding site antibody, is broad and potent in neutralization but does not induce conformational changes characteristic of CD4.

Falkowska, Emilia; Ramos, Alejandra; Feng, Yu; Zhou, Tongqing; Moquin, Stephanie; Walker, Laura M; Wu, Xueling; Seaman, Michael S; Wrin, Terri; Kwong, Peter D; Wyatt, Richard T; Mascola, John R; Poignard, Pascal; Burton, Dennis R.
J Virol; 86(8): 4394-403, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-22345481