Rearrangement of HMGA2 in a case of infantile lipoblastoma without Plag1 alteration.
Pedeutour, Florence; Deville, Anne; Steyaert, Henri; Ranchere-Vince, Dominique; Ambrosetti, Damien; Sirvent, Nicolas.
Pediatr Blood Cancer
; 58(5): 798-800, 2012 May.
Artigo em Inglês | MEDLINE | ID: mdl-22223189
Expression levels of HMGA2 in adipocytic tumors correlate with morphologic and cytogenetic subgroups.
Truncation and fusion of HMGA2 in lipomas with rearrangements of 5q32-->q33 and 12q14-->q15.
HMGA2 rearrangements are rare in benign lipomatous lesions of the nervous system.
Fusion of the HMGA2 and NFIB genes in lipoma.
Let-7 microRNA and HMGA2 levels of expression are not inversely linked in adipocytic tumors: analysis of 56 lipomas and liposarcomas with molecular cytogenetic data.
Disruption and aberrant expression of HMGA2 as a consequence of diverse chromosomal translocations in myeloid malignancies.
Thymolipoma: clues to pathogenesis revealed by cytogenetics.
Rearrangements of chromosome bands 15q12-q21 are secondary to HMGA2 deregulation in conventional lipoma.
Identification of PPAP2B as a novel recurrent translocation partner gene of HMGA2 in lipomas.
Identification of novel HMGA2 fusion sequences in lipoma: evidence that deletion of let-7 miRNA consensus binding site 1 in the HMGA2 3' UTR is not critical for HMGA2 transcriptional upregulation.