Activation of the NLRP3 inflammasome by Mycobacterium tuberculosis is uncoupled from susceptibility to active tuberculosis.
Dorhoi, Anca; Nouailles, Geraldine; Jörg, Sabine; Hagens, Kristine; Heinemann, Ellen; Pradl, Lydia; Oberbeck-Müller, Dagmar; Duque-Correa, Maria Adelaida; Reece, Stephen T; Ruland, Jürgen; Brosch, Roland; Tschopp, Jürg; Gross, Olaf; Kaufmann, Stefan H E.
Eur J Immunol
; 42(2): 374-84, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22101787
Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity.
Macrophages: development and tissue specialization.
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
An NLRP7-containing inflammasome mediates recognition of microbial lipopeptides in human macrophages.
Inflammasome activation by Campylobacter jejuni.
Kâº drops tilt the NLRP3 inflammasome.
Cell swelling and the NLRP3 inflammasome.
NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component.
Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage.