Effects of PEGylation and immune complex formation on the pharmacokinetics and biodistribution of recombinant interleukin 10 in mice.
Alvarez, Hamsell M; So, On-Yee; Hsieh, SuChun; Shinsky-Bjorde, Natasha; Ma, Huiping; Song, Yaoli; Pang, Yinuo; Marian, Melinda; Escandón, Enrique.
Drug Metab Dispos
; 40(2): 360-73, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22083830
Purification and characterization of human IL-10/Fc fusion protein expressed in Pichia pastoris.
Deducing receptor signaling parameters from in vivo analysis: LuxN/AI-1 quorum sensing in Vibrio harveyi.
A Broad-Spectrum Inhibitor of CRISPR-Cas9.
Structural basis for inhibition of a response regulator of σ<sup>S</sup> stability by a ClpXP antiadaptor.
Blocking IL-10 signalling at the time of immunization does not increase unwanted side effects in mice.
Novel morpholine scaffolds as selective dopamine (DA) D3 receptor antagonists.
A Convenient Approach to Stereoisomeric Iminocyclitols: Generation of Potent Brain-Permeable OGA Inhibitors.
How Ligands Illuminate GPCR Molecular Pharmacology.
SnapShot: GPCR-Ligand Interactions.
2-Aminomethylthieno[3,2-d]pyrimidin-4(3H)-ones bearing 3-methylpyrazole hinge binding moiety: Highly potent, selective, and time-dependent inhibitors of Cdc7 kinase.