Normal mammalian cells negatively regulate telomere length by telomere trimming.
Pickett, Hilda A; Henson, Jeremy D; Au, Amy Y M; Neumann, Axel A; Reddel, Roger R.
Hum Mol Genet
; 20(23): 4684-92, 2011 Dec 01.
Artigo em Inglês | MEDLINE | ID: mdl-21903669
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Targeted Degradation of CTCF Decouples Local Insulation of Chromosome Domains from Genomic Compartmentalization.
Whole chromosome loss and associated breakage-fusion-bridge cycles transform mouse tetraploid cells.
ATR-X syndrome protein targets tandem repeats and influences allele-specific expression in a size-dependent manner.
SMCHD1 Merges Chromosome Compartments and Assists Formation of Super-Structures on the Inactive X.
Chromosomal Loop Domains Direct the Recombination of Antigen Receptor Genes.
Chromosomes Progress to Metaphase in Multiple Discrete Steps via Global Compaction/Expansion Cycles.
Cell-cycle dynamics of chromosomal organization at single-cell resolution.
Interchromosomal association and gene regulation in trans.
Re-engineering the zinc fingers of PRDM9 reverses hybrid sterility in mice.