Effectiveness of the local or oral delivery of the novel naphthopterocarpanquinone LQB-118 against cutaneous leishmaniasis.
da Cunha-Júnior, Edézio Ferreira; Pacienza-Lima, Wallace; Ribeiro, Grazielle Alves; Netto, Chaquip Daher; do Canto-Cavalheiro, Marilene Marcuzzo; da Silva, Alcides José Monteiro; Costa, Paulo Roberto Ribeiro; Rossi-Bergmann, Bartira; Torres-Santos, Eduardo Caio.
J Antimicrob Chemother
; 66(7): 1555-9, 2011 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-21531758
Concentrations of buparvaquone in milk and tissue of dairy cows.
Evaluation on the leishmanicidal activity of 2-N,N'-dialkylamino-1,4-naphthoquinone derivatives.
Antileishmanial Activity of 2-Methoxy-4H-spiro-[naphthalene-1,2'-oxiran]-4-one (Epoxymethoxy-lawsone): A Promising New Drug Candidate for Leishmaniasis Treatment.
Preparative chiral separation and absolute configuration of the synthetic pterocarpanquinone LQB-118.
Efficacy of lapachol on treatment of cutaneous and visceral leishmaniasis.
Anti-inflammatory properties of pterocarpanquinone LQB-118 in mice.
Evidences for leishmanicidal activity of the naphthoquinone derivative epoxy-α-lapachone.
Preclinical Studies Evaluating Subacute Toxicity and Therapeutic Efficacy of LQB-118 in Experimental Visceral Leishmaniasis.
Antileishmanial activity of a naphthoquinone derivate against promastigote and amastigote stages of Leishmania infantum and Leishmania amazonensis and its mechanism of action against L. amazonensis species.
Synthesis, leishmanicidal activity and theoretical evaluations of a series of substituted bis-2-hydroxy-1,4-naphthoquinones.