MMSET is highly expressed and associated with aggressiveness in neuroblastoma.
Hudlebusch, Heidi Rye; Skotte, Julie; Santoni-Rugiu, Eric; Zimling, Zarah Glad; Lees, Michael James; Simon, Ronald; Sauter, Guido; Rota, Rossella; De Ioris, Maria Antonietta; Quarto, Micaela; Johansen, Jens Vilstrup; Jørgensen, Mette; Rechnitzer, Catherine; Maroun, Lisa Leth; Schrøder, Henrik; Petersen, Bodil Laub; Helin, Kristian.
; 71(12): 4226-35, 2011 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-21527557
Microcephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiation.
Transition state for the NSD2-catalyzed methylation of histone H3 lysine 36.
Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.
Suv39h-dependent H3K9me3 marks intact retrotransposons and silences LINE elements in mouse embryonic stem cells.
Cancers and the NSD family of histone lysine methyltransferases.
A subset of the histone H3 lysine 9 methyltransferases Suv39h1, G9a, GLP, and SETDB1 participate in a multimeric complex.
Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells.
A PWWP Domain of Histone-Lysine N-Methyltransferase NSD2 Binds to Dimethylated Lys-36 of Histone H3 and Regulates NSD2 Function at Chromatin.
Polycomb protein Ezh1 promotes RNA polymerase II elongation.
Total kinetic analysis reveals how combinatorial methylation patterns are established on lysines 27 and 36 of histone H3.