Discovery of MK-0952, a selective PDE4 inhibitor for the treatment of long-term memory loss and mild cognitive impairment.

Gallant, Michel; Aspiotis, Renee; Day, Stephen; Dias, Rebecca; Dubé, Daniel; Dubé, Laurence; Friesen, Richard W; Girard, Mario; Guay, Daniel; Hamel, Pierre; Huang, Zheng; Lacombe, Patrick; Laliberté, Sebastien; Lévesque, Jean-François; Liu, Susana; Macdonald, Dwight; Mancini, Joseph; Nicholson, Donald W; Styhler, Angela; Townson, Karen; Waters, Kerry; Young, Robert N; Girard, Yves.
Bioorg Med Chem Lett; 20(22): 6387-93, 2010 Nov 15.
Artigo em Inglês | MEDLINE | ID: mdl-20933411