Addressing time-dependent CYP 3A4 inhibition observed in a novel series of substituted amino propanamide renin inhibitors, a case study.

Chen, Austin; Dubé, Daniel; Dubé, Laurence; Gagné, Sébastien; Gallant, Michel; Gaudreault, Mireille; Grimm, Erich; Houle, Robert; Lacombe, Patrick; Laliberté, Sébastien; Liu, Suzanna; MacDonald, Dwight; Mackay, Bruce; Martin, David; McKay, Dan; Powell, David; Lévesque, Jean-François.
Bioorg Med Chem Lett; 20(17): 5074-9, 2010 Sep 01.
Artigo em Inglês | MEDLINE | ID: mdl-20673718