High-sensitivity nanoLC-MS/MS analysis of urinary desmosine and isodesmosine.
Boutin, Michel; Berthelette, Carl; Gervais, François G; Scholand, Mary-Beth; Hoidal, John; Leppert, Mark F; Bateman, Kevin P; Thibault, Pierre.
; 81(5): 1881-7, 2009 Mar 01.
Artigo em Inglês | MEDLINE | ID: mdl-19178285
Measurement of urinary total desmosine and isodesmosine using isotope-dilution liquid chromatography-tandem mass spectrometry.
Quantification of desmosine and isodesmosine using MALDI-ion trap tandem mass spectrometry.
Urinary desmosine is associated with emphysema severity and frequent exacerbation in patients with COPD.
Total desmosines in plasma and urine correlate with lung function.
Desmosine, a biomarker for COPD: old and in the way.
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Determination of free desmosine and isodesmosine as urinary biomarkers of lung disorder using ultra performance liquid chromatography-ion mobility-mass spectrometry.
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Development of a robust LC-MS/MS method for determination of desmosine and isodesmosine in human urine.
The effect of tiotropium therapy on markers of elastin degradation in COPD.