Homeodomain transcription factor NKX2.2 functions in immature cells to control enteroendocrine differentiation and is expressed in gastrointestinal neuroendocrine tumors.
Wang, Yu-Cheng; Gallego-Arteche, Emerick; Iezza, Gioia; Yuan, Xiaochen; Matli, Mary R; Choo, Su-Pin; Zuraek, Marlene B; Gogia, Ravi; Lynn, Francis C; German, Michael S; Bergsland, Emily K; Donner, David B; Warren, Robert S; Nakakura, Eric K.
Endocr Relat Cancer
; 16(1): 267-79, 2009 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-18987169
Afadin and RhoA control pancreatic endocrine mass via lumen morphogenesis.
Taming the young and restless--epigenetic gene regulation in pancreas and beta-cell precursors.
Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells.
Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche.
Polyclonal Crypt Genesis and Development of Familial Small Intestinal Neuroendocrine Tumors.
Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation.
Regulation of terminal differentiation programs in the nervous system.
Transcriptional control of early T and B cell developmental choices.
Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.
An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration.