Bradykinin B2 Receptors of dendritic cells, acting as sensors of kinins proteolytically released by Trypanosoma cruzi, are critical for the development of protective type-1 responses.
Monteiro, Ana Carolina; Schmitz, Verônica; Morrot, Alexandre; de Arruda, Luciana Barros; Nagajyothi, Fnu; Granato, Alessandra; Pesquero, João B; Müller-Esterl, Werner; Tanowitz, Herbert B; Scharfstein, Julio.
; 3(11): e185, 2007 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-18052532
The role of N-terminal and C-terminal Arg residues from BK on interaction with kinin B2 receptor.
Kinin danger signals proteolytically released by gingipain induce Fimbriae-specific IFN-gamma- and IL-17-producing T cells in mice infected intramucosally with Porphyromonas gingivalis.
Gangliosides and chondroitin sulfate desensitize and internalize B2 bradykinin receptors.
Bradykinin B2 and dopamine D2 receptors form a functional dimer.
Beta-Arrestin1 Prevents Preeclampsia by Downregulation of Mechanosensitive AT1-B2 Receptor Heteromers.
Pro-angiogenic effect of human kallikrein-related peptidase 12 (KLK12) in lung endothelial cells does not depend on kinin-mediated activation of B2 receptor.
Bradykinin sensitizes the cough reflex via a B<sub>2</sub> receptor dependent activation of TRPV1 and TRPA1 channels through metabolites of cyclooxygenase and 12-lipoxygenase.
Kinin-B2 receptor activity determines the differentiation fate of neural stem cells.
Tissue kallikrein is essential for invasive capacity of circulating proangiogenic cells.
Novel insights into the critical role of bradykinin and the kinin B2 receptor for vascular recruitment of circulating endothelial repair-promoting mononuclear cell subsets: alterations in patients with coronary disease.