Preclinical and clinical safety of monoclonal antibodies.
Tabrizi, Mohammad A; Roskos, Lorin K.
Drug Discov Today
; 12(13-14): 540-7, 2007 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-17631248
Using the Lessons Learned From the Clinic to Improve the Preclinical Development of Antibody Drug Conjugates.
Optimized nonclinical safety assessment strategies supporting clinical development of therapeutic monoclonal antibodies targeting inflammatory diseases.
Drug Development of Therapeutic Monoclonal Antibodies.
Preclinical Pharmacokinetic Considerations for the Development of Antibody Drug Conjugates.
Applicability of predictive toxicology methods for monoclonal antibody therapeutics: status Quo and scope.
Therapeutic antibodies for the treatment of pancreatic cancer.
Humanized antibody to the alpha4beta7 integrin for induction of remission in ulcerative colitis.
Use of tissue cross-reactivity studies in the development of antibody-based biopharmaceuticals: history, experience, methodology, and future directions.
Drug evaluation: adecatumumab, an engineered human anti-EpCAM antibody.