Structure-activity relationship in the 3-iodo-4-phenoxypyridinone (IOPY) series: The nature of the C-3 substituent on anti-HIV activity.
Benjahad, Abdellah; Oumouch, Said; Guillemont, Jerôme; Pasquier, Elisabeth; Mabire, Dominique; Andries, Koen; Nguyen, Chi Hung; Grierson, David S.
Bioorg Med Chem Lett
; 17(3): 712-6, 2007 Feb 01.
Artigo em Inglês | MEDLINE | ID: mdl-17157017
Discovery of 2-pyridone derivatives as potent HIV-1 NNRTIs using molecular hybridization based on crystallographic overlays.
Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography.
CD8(+) T Cells and cART: A Dynamic Duo?
Focus on Chirality of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors.
Synthesis and evaluation of pyridinium polyoxometalates as anti-HIV-1 agents.
Aspernigrins with anti-HIV-1 activities from the marine-derived fungus Aspergillus niger SCSIO Jcsw6F30.
Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses.
Design, synthesis and anti-HIV-1 evaluation of hydrazide-based peptidomimetics as selective gelatinase inhibitors.
Effect of Rifampin on the Single-Dose Pharmacokinetics of Oral Cabotegravir in Healthy Subjects.
Design, synthesis and biological evaluation of indole derivatives as Vif inhibitors.