Colon carcinoma cells induce CXCL11-dependent migration of CXCR3-expressing cytotoxic T lymphocytes in organotypic culture.
Berencsi, Klara; Meropol, Neal J; Hoffman, John P; Sigurdson, Elin; Giles, Lydia; Rani, Pyapalli; Somasundaram, Rajasekharan; Zhang, Tianqian; Kalabis, Jiri; Caputo, Laura; Furth, Emma; Swoboda, Rolf; Marincola, Francesco; Herlyn, Dorothee.
Cancer Immunol Immunother
; 56(3): 359-70, 2007 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-16783574
NMR structure of CXCR3 binding chemokine CXCL11 (ITAC).
Blocking interferon Î³ reduces expression of chemokines CXCL9, CXCL10 and CXCL11 and decreases macrophage infiltration in ex vivo cultured arteries from patients with giant cell arteritis.
Increased expression of CXCR3 and CCR5 on memory CD4+ T-cells migrating into the cerebrospinal fluid of patients with neuroborreliosis: the role of CXCL10 and CXCL11.
Aberrant chemokine receptor expression and chemokine production by Langerhans cells underlies the pathogenesis of Langerhans cell histiocytosis.
Elevated serum levels of the CXCR3 chemokine ITAC are associated with the development of transplant coronary artery disease.
Synergistic induction of CXCL9 and CXCL11 by Toll-like receptor ligands and interferon-gamma in fibroblasts correlates with elevated levels of CXCR3 ligands in septic arthritis synovial fluids.
Dipeptidyl peptidase IV (CD26) on T cells cleaves the CXC chemokine CXCL11 (I-TAC) and abolishes the stimulating but not the desensitizing potential of the chemokine.
Irradiation of breast cancer cells enhances CXCL16 ligand expression and induces the migration of natural killer cells expressing the CXCR6 receptor.
Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells.
CXCR3 requires tyrosine sulfation for ligand binding and a second extracellular loop arginine residue for ligand-induced chemotaxis.