Effect of interferon alpha on MHC class II gene expression in ex vivo human islet tissue.
Harris, Paul E; Malanga, Donatella; Liu, Zhuoro; Hardy, Mark A; Souza, Fabiola; Del Pozzo, Giovanna; Winchester, Robert J; Maffei, Antonella.
Biochim Biophys Acta
; 1762(6): 627-35, 2006 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-16782520
Human islets and dendritic cells generate post-translationally modified islet autoantigens.
IFN-α induces a preferential long-lasting expression of MHC class I in human pancreatic beta cells.
A preliminary analysis of hepatitis C virus in pancreatic islet cells.
A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets.
Adenoviral-mediated transduction of human pancreatic islets: importance of adenoviral genome for cell viability and association with a deficient antiviral response.
Accelerated progression from islet autoimmunity to diabetes is causing the escalating incidence of type 1 diabetes in young children.
Predicting progression to type 1 diabetes from ages 3 to 6 in islet autoantibody positive TEDDY children.
The 6 year incidence of diabetes-associated autoantibodies in genetically at-risk children: the TEDDY study.
Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease.
Non-HLA type 1 diabetes genes modulate disease risk together with HLA-DQ and islet autoantibodies.