Pesquisa | Biblioteca Virtual em Saúde

1.

Targeting the adaptability of heterogeneous aneuploids.

Chen, Guangbo; Mulla, Wahid A; Kucharavy, Andrei; Tsai, Hung-Ji; Rubinstein, Boris; Conkright, Juliana; McCroskey, Scott; Bradford, William D; Weems, Lauren; Haug, Jeff S; Seidel, Chris W; Berman, Judith; Li, Rong.

Cell; 160(4): 771-784, 2015 Feb 12.

Artigo em Inglês | MEDLINE | ID: mdl-25679766

2.

Unraveling the biology of a fungal meningitis pathogen using chemical genetics.

Brown, Jessica C S; Nelson, Justin; VanderSluis, Benjamin; Deshpande, Raamesh; Butts, Arielle; Kagan, Sarah; Polacheck, Itzhack; Krysan, Damian J; Myers, Chad L; Madhani, Hiten D.

Cell; 159(5): 1168-1187, 2014 Nov 20.

Artigo em Inglês | MEDLINE | ID: mdl-25416953

3.

Molecular Basis of the Rapamycin Insensitivity of Target Of Rapamycin Complex 2.

Gaubitz, Christl; Oliveira, Taiana M; Prouteau, Manoel; Leitner, Alexander; Karuppasamy, Manikandan; Konstantinidou, Georgia; Rispal, Delphine; Eltschinger, Sandra; Robinson, Graham C; Thore, Stéphane; Aebersold, Ruedi; Schaffitzel, Christiane; Loewith, Robbie.

Mol Cell; 58(6): 977-88, 2015 Jun 18.

Artigo em Inglês | MEDLINE | ID: mdl-26028537

4.

Changes in incidence and antifungal drug resistance in candidemia: results from population-based laboratory surveillance in Atlanta and Baltimore, 2008-2011.

Cleveland, Angela Ahlquist; Farley, Monica M; Harrison, Lee H; Stein, Betsy; Hollick, Rosemary; Lockhart, Shawn R; Magill, Shelley S; Derado, Gordana; Park, Benjamin J; Chiller, Tom M.

Clin Infect Dis; 55(10): 1352-61, 2012 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-22893576

5.

Molecular Evolution of Antifungal Drug Resistance.

Robbins, Nicole; Caplan, Tavia; Cowen, Leah E.

Annu Rev Microbiol; 71: 753-775, 2017 09 08.

Artigo em Inglês | MEDLINE | ID: mdl-28886681

6.

Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction.

Nishikawa, Joy L; Boeszoermenyi, Andras; Vale-Silva, Luis A; Torelli, Riccardo; Posteraro, Brunella; Sohn, Yoo-Jin; Ji, Fei; Gelev, Vladimir; Sanglard, Dominique; Sanguinetti, Maurizio; Sadreyev, Ruslan I; Mukherjee, Goutam; Bhyravabhotla, Jayaram; Buhrlage, Sara J; Gray, Nathanael S; Wagner, Gerhard; Näär, Anders M; Arthanari, Haribabu.

Nature; 530(7591): 485-9, 2016 Feb 25.

Artigo em Inglês | MEDLINE | ID: mdl-26886795

7.

Broad antifungal resistance mediated by RNAi-dependent epimutation in the basal human fungal pathogen Mucor circinelloides.

Chang, Zanetta; Billmyre, R Blake; Lee, Soo Chan; Heitman, Joseph.

PLoS Genet; 15(2): e1007957, 2019 02.

Artigo em Inglês | MEDLINE | ID: mdl-30742617

8.

Commercial AHAS-inhibiting herbicides are promising drug leads for the treatment of human fungal pathogenic infections.

Garcia, Mario D; Chua, Sheena M H; Low, Yu-Shang; Lee, Yu-Ting; Agnew-Francis, Kylie; Wang, Jian-Guo; Nouwens, Amanda; Lonhienne, Thierry; Williams, Craig M; Fraser, James A; Guddat, Luke W.

Proc Natl Acad Sci U S A; 115(41): E9649-E9658, 2018 10 09.

Artigo em Inglês | MEDLINE | ID: mdl-30249642

9.

Global analysis of genetic circuitry and adaptive mechanisms enabling resistance to the azole antifungal drugs.

Mount, Harley O'Connor; Revie, Nicole M; Todd, Robert T; Anstett, Kaitlin; Collins, Cathy; Costanzo, Michael; Boone, Charles; Robbins, Nicole; Selmecki, Anna; Cowen, Leah E.

PLoS Genet; 14(4): e1007319, 2018 04.

Artigo em Inglês | MEDLINE | ID: mdl-29702647

10.

Bioactive xanthones from the roots of Hypericum perforatum (common St John's wort).

Crockett, Sara L; Poller, Birgit; Tabanca, Nurhayat; Pferschy-Wenzig, Eva-Maria; Kunert, Olaf; Wedge, David E; Bucar, Franz.

J Sci Food Agric; 91(3): 428-34, 2011 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-21218475

11.

Candida parapsilosis: from Genes to the Bedside.

Tóth, Renáta; Nosek, Jozef; Mora-Montes, Héctor M; Gabaldon, Toni; Bliss, Joseph M; Nosanchuk, Joshua D; Turner, Siobhán A; Butler, Geraldine; Vágvölgyi, Csaba; Gácser, Attila.

Clin Microbiol Rev; 32(2)2019 03 20.

Artigo em Inglês | MEDLINE | ID: mdl-30814115

12.

Cell biology of microbes and pharmacology of antimicrobial drugs explored by Atomic Force Microscopy.

Formosa-Dague, Cécile; Duval, Raphaël Emmanuel; Dague, Etienne.

Semin Cell Dev Biol; 73: 165-176, 2018 01.

Artigo em Inglês | MEDLINE | ID: mdl-28668355

13.

Functional analysis of Hsh155/SF3b1 interactions with the U2 snRNA/branch site duplex.

Carrocci, Tucker J; Paulson, Joshua C; Hoskins, Aaron A.

RNA; 24(8): 1028-1040, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-29752352

14.

CGA-N9, an antimicrobial peptide derived from chromogranin A: direct cell penetration of and endocytosis by Candida tropicalis.

Li, Ruifang; Chen, Chen; Zhu, Sha; Wang, Xueqin; Yang, Yanhui; Shi, Weini; Chen, Sijia; Wang, Congcong; Yan, Lixing; Shi, Jiaofan.

Biochem J; 476(3): 483-497, 2019 02 05.

Artigo em Inglês | MEDLINE | ID: mdl-30610128

15.

Triazoles inhibit cholesterol export from lysosomes by binding to NPC1.

Trinh, Michael N; Lu, Feiran; Li, Xiaochun; Das, Akash; Liang, Qiren; De Brabander, Jef K; Brown, Michael S; Goldstein, Joseph L.

Proc Natl Acad Sci U S A; 114(1): 89-94, 2017 01 03.

Artigo em Inglês | MEDLINE | ID: mdl-27994139

16.

Phosphate is the third nutrient monitored by TOR in Candida albicans and provides a target for fungal-specific indirect TOR inhibition.

Liu, Ning-Ning; Flanagan, Peter R; Zeng, Jumei; Jani, Niketa M; Cardenas, Maria E; Moran, Gary P; Köhler, Julia R.

Proc Natl Acad Sci U S A; 114(24): 6346-6351, 2017 06 13.

Artigo em Inglês | MEDLINE | ID: mdl-28566496

17.

Azole resistance in a Candida albicans mutant lacking the ABC transporter CDR6/ROA1 depends on TOR signaling.

Khandelwal, Nitesh Kumar; Chauhan, Neeraj; Sarkar, Parijat; Esquivel, Brooke D; Coccetti, Paola; Singh, Ashutosh; Coste, Alix T; Gupta, Meghna; Sanglard, Dominique; White, Theodore C; Chauvel, Murielle; d'Enfert, Christophe; Chattopadhyay, Amitabha; Gaur, Naseem A; Mondal, Alok Kumar; Prasad, Rajendra.

J Biol Chem; 293(2): 412-432, 2018 01 12.

Artigo em Inglês | MEDLINE | ID: mdl-29158264

18.

Emerging Mechanisms of Drug Resistance in Candida albicans.

Prasad, Rajendra; Nair, Remya; Banerjee, Atanu.

Prog Mol Subcell Biol; 58: 135-153, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-30911892

19.

Genome-Wide Response to Drugs and Stress in the Pathogenic Yeast Candida glabrata.

Pais, Pedro; Galocha, Mónica; Teixeira, Miguel Cacho.

Prog Mol Subcell Biol; 58: 155-193, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-30911893

20.

Genomics-driven discovery of a biosynthetic gene cluster required for the synthesis of BII-Rafflesfungin from the fungus Phoma sp. F3723.

Sinha, Swati; Nge, Choy-Eng; Leong, Chung Yan; Ng, Veronica; Crasta, Sharon; Alfatah, Mohammad; Goh, Falicia; Low, Kia-Ngee; Zhang, Huibin; Arumugam, Prakash; Lezhava, Alexander; Chen, Swaine L; Kanagasundaram, Yoganathan; Ng, Siew Bee; Eisenhaber, Frank; Eisenhaber, Birgit.

BMC Genomics; 20(1): 374, 2019 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-31088369

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