Pesquisa | Biblioteca Virtual em Saúde

1.

Non-cell-autonomous tumor suppression by p53.

Lujambio, Amaia; Akkari, Leila; Simon, Janelle; Grace, Danielle; Tschaharganeh, Darjus F; Bolden, Jessica E; Zhao, Zhen; Thapar, Vishal; Joyce, Johanna A; Krizhanovsky, Valery; Lowe, Scott W.

Cell; 153(2): 449-60, 2013 Apr 11.

Artigo em Inglês | MEDLINE | ID: mdl-23562644

2.

Establishment and Dysfunction of the Blood-Brain Barrier.

Zhao, Zhen; Nelson, Amy R; Betsholtz, Christer; Zlokovic, Berislav V.

Cell; 163(5): 1064-1078, 2015 Nov 19.

Artigo em Inglês | MEDLINE | ID: mdl-26590417

3.

Blood-Brain Barrier: From Physiology to Disease and Back.

Sweeney, Melanie D; Zhao, Zhen; Montagne, Axel; Nelson, Amy R; Zlokovic, Berislav V.

Physiol Rev; 99(1): 21-78, 2019 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-30280653

4.

Senescence-associated reprogramming promotes cancer stemness.

Milanovic, Maja; Fan, Dorothy N Y; Belenki, Dimitri; Däbritz, J Henry M; Zhao, Zhen; Yu, Yong; Dörr, Jan R; Dimitrova, Lora; Lenze, Dido; Monteiro Barbosa, Ines A; Mendoza-Parra, Marco A; Kanashova, Tamara; Metzner, Marlen; Pardon, Katharina; Reimann, Maurice; Trumpp, Andreas; Dörken, Bernd; Zuber, Johannes; Gronemeyer, Hinrich; Hummel, Michael; Dittmar, Gunnar; Lee, Soyoung; Schmitt, Clemens A.

Nature; 553(7686): 96-100, 2018 01 04.

Artigo em Inglês | MEDLINE | ID: mdl-29258294

5.

Sensitive tumour detection and classification using plasma cell-free DNA methylomes.

Shen, Shu Yi; Singhania, Rajat; Fehringer, Gordon; Chakravarthy, Ankur; Roehrl, Michael H A; Chadwick, Dianne; Zuzarte, Philip C; Borgida, Ayelet; Wang, Ting Ting; Li, Tiantian; Kis, Olena; Zhao, Zhen; Spreafico, Anna; Medina, Tiago da Silva; Wang, Yadon; Roulois, David; Ettayebi, Ilias; Chen, Zhuo; Chow, Signy; Murphy, Tracy; Arruda, Andrea; O'Kane, Grainne M; Liu, Jessica; Mansour, Mark; McPherson, John D; O'Brien, Catherine; Leighl, Natasha; Bedard, Philippe L; Fleshner, Neil; Liu, Geoffrey; Minden, Mark D; Gallinger, Steven; Goldenberg, Anna; Pugh, Trevor J; Hoffman, Michael M; Bratman, Scott V; Hung, Rayjean J; De Carvalho, Daniel D.

Nature; 563(7732): 579-583, 2018 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-30429608

6.

Prediction of acute myeloid leukaemia risk in healthy individuals.

Abelson, Sagi; Collord, Grace; Ng, Stanley W K; Weissbrod, Omer; Mendelson Cohen, Netta; Niemeyer, Elisabeth; Barda, Noam; Zuzarte, Philip C; Heisler, Lawrence; Sundaravadanam, Yogi; Luben, Robert; Hayat, Shabina; Wang, Ting Ting; Zhao, Zhen; Cirlan, Iulia; Pugh, Trevor J; Soave, David; Ng, Karen; Latimer, Calli; Hardy, Claire; Raine, Keiran; Jones, David; Hoult, Diana; Britten, Abigail; McPherson, John D; Johansson, Mattias; Mbabaali, Faridah; Eagles, Jenna; Miller, Jessica K; Pasternack, Danielle; Timms, Lee; Krzyzanowski, Paul; Awadalla, Philip; Costa, Rui; Segal, Eran; Bratman, Scott V; Beer, Philip; Behjati, Sam; Martincorena, Inigo; Wang, Jean C Y; Bowles, Kristian M; Quirós, J Ramón; Karakatsani, Anna; La Vecchia, Carlo; Trichopoulou, Antonia; Salamanca-Fernández, Elena; Huerta, José M; Barricarte, Aurelio; Travis, Ruth C; Tumino, Rosario.

Nature; 559(7714): 400-404, 2018 07.

Artigo em Inglês | MEDLINE | ID: mdl-29988082

7.

DNA methylation analysis and editing in single mammalian oocytes.

Wei, Yanchang; Lang, Jingwen; Zhang, Qian; Yang, Cai-Rong; Zhao, Zhen-Ao; Zhang, Yixin; Du, Yanzhi; Sun, Yun.

Proc Natl Acad Sci U S A; 116(20): 9883-9892, 2019 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-31010926

8.

High efficiency error suppression for accurate detection of low-frequency variants.

Wang, Ting Ting; Abelson, Sagi; Zou, Jinfeng; Li, Tiantian; Zhao, Zhen; Dick, John E; Shlush, Liran I; Pugh, Trevor J; Bratman, Scott V.

Nucleic Acids Res; 47(15): e87, 2019 09 05.

Artigo em Inglês | MEDLINE | ID: mdl-31127310

9.

PAR1 biased signaling is required for activated protein C in vivo benefits in sepsis and stroke.

Sinha, Ranjeet K; Wang, Yaoming; Zhao, Zhen; Xu, Xiao; Burnier, Laurent; Gupta, Naveen; Fernández, José A; Martin, Greg; Kupriyanov, Sergey; Mosnier, Laurent O; Zlokovic, Berislav V; Griffin, John H.

Blood; 131(11): 1163-1171, 2018 Mar 15.

Artigo em Inglês | MEDLINE | ID: mdl-29343482

10.

Lack of Cardiac Improvement After Cardiosphere-Derived Cell Transplantation in Aging Mouse Hearts.

Zhao, Zhen-Ao; Han, Xinglong; Lei, Wei; Li, Jingjing; Yang, Zhuangzhuang; Wu, Jie; Yao, Mengchao; Lu, Xing-Ai; He, Lingjuan; Chen, Yihuan; Zhou, Bin; Hu, Shijun.

Circ Res; 123(10): e21-e31, 2018 Oct 26.

Artigo em Inglês | MEDLINE | ID: mdl-30359191

11.

Parallel Analyses of Somatic Mutations in Plasma Circulating Tumor DNA (ctDNA) and Matched Tumor Tissues in Early-Stage Breast Cancer.

Zhang, Xianyu; Zhao, Weiwei; Wei, Wei; You, Zilong; Ou, Xiaohua; Sun, Mingming; Yin, Yanling; Tang, Xiaoyan; Zhao, Zhen; Hu, Changming; Liu, Feifei; Deng, Junhao; Mao, Linlin; Zhou, Danyan; Ren, Yuxia; Li, Xiaoxia; Zhang, Shangfei; Liu, Chang; Geng, Jingshu; Yao, Guodong; Song, Bingbing; Liu, Yupeng; Li, Dalin; Jiang, Yongdong; Chen, Yanbo; Zhao, Yashuang; Yu, Shihui; Pang, Da.

Clin Cancer Res; 25(21): 6546-6553, 2019 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-31350313

12.

Quantification of circulating Mycobacterium tuberculosis antigen peptides allows rapid diagnosis of active disease and treatment monitoring.

Liu, Chang; Zhao, Zhen; Fan, Jia; Lyon, Christopher J; Wu, Hung-Jen; Nedelkov, Dobrin; Zelazny, Adrian M; Olivier, Kenneth N; Cazares, Lisa H; Holland, Steven M; Graviss, Edward A; Hu, Ye.

Proc Natl Acad Sci U S A; 114(15): 3969-3974, 2017 04 11.

Artigo em Inglês | MEDLINE | ID: mdl-28348223

13.

Dynamic transcriptome profiling in DNA damage-induced cellular senescence and transient cell-cycle arrest.

Zhao, Zhen; Dong, Qiongye; Liu, Xuehui; Wei, Lei; Liu, Liyang; Li, Yanda; Wang, Xiaowo.

Genomics; 2019 Jul 31.

Artigo em Inglês | MEDLINE | ID: mdl-31376528

14.

The atypical E2F family member E2F7 couples the p53 and RB pathways during cellular senescence.

Aksoy, Ozlem; Chicas, Agustin; Zeng, Tianying; Zhao, Zhen; McCurrach, Mila; Wang, Xiaowo; Lowe, Scott W.

Genes Dev; 26(14): 1546-57, 2012 Jul 15.

Artigo em Inglês | MEDLINE | ID: mdl-22802529

15.

MIR148A family regulates cardiomyocyte differentiation of human embryonic stem cells by inhibiting the DLL1-mediated NOTCH signaling pathway.

Fang, Xing; Miao, Shumei; Yu, You; Ding, Fengyue; Han, Xinglong; Wu, Hongchun; Zhao, Zhen-Ao; Wang, Yongming; Hu, Shijun; Lei, Wei.

J Mol Cell Cardiol; 134: 1-12, 2019 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-31233755

16.

CXCL12 promotes atherosclerosis by downregulating ABCA1 expression via the CXCR4/GSK3ß/ß-catenin^T120/TCF21 pathway.

Gao, Jia-Hui; He, Lin-Hao; Yu, Xiao-Hua; Zhao, Zhen-Wang; Wang, Gang; Zou, Jin; Wen, Feng-Jiao; Zhou, Li; Wan, Xiang-Jun; Zhang, Da-Wei; Tang, Chao-Ke.

J Lipid Res; 60(12): 2020-2033, 2019 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-31662443

17.

The bifunctional SDF-1-AnxA5 fusion protein protects cardiac function after myocardial infarction.

Huang, Fang-Yang; Xia, Tian-Li; Li, Jun-Li; Li, Chang-Ming; Zhao, Zhen-Gang; Lei, Wen-Hua; Chen, Li; Liao, Yan-Biao; Xiao, Dan; Peng, Yong; Wang, Yun-Bing; Liu, Xiao-Jing; Chen, Mao.

J Cell Mol Med; 23(11): 7673-7684, 2019 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-31468674

18.

MicroRNA-1271 functions as a potential tumor suppressor in hepatitis B virus-associated hepatocellular carcinoma through the AMPK signaling pathway by binding to CCNA1.

Chen, Yang; Zhao, Zhen-Xian; Huang, Fei; Yuan, Xiao-Wei; Deng, Liang; Tang, Di.

J Cell Physiol; 234(4): 3555-3569, 2019 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-30565670

19.

Highly Enantioselective Cross-Electrophile Aryl-Alkenylation of Unactivated Alkenes.

Tian, Zhi-Xiong; Qiao, Jin-Bao; Xu, Guang-Li; Pang, Xiaobo; Qi, Liangliang; Ma, Wei-Yuan; Zhao, Zhen-Zhen; Duan, Jicheng; Du, Yun-Fei; Su, Peifeng; Liu, Xue-Yuan; Shu, Xing-Zhong.

J Am Chem Soc; 141(18): 7637-7643, 2019 May 08.

Artigo em Inglês | MEDLINE | ID: mdl-31002758

20.

Lixisenatide enhances mitochondrial biogenesis and function through regulating the CREB/PGC-1α pathway.

Zhao, Zhen; Pu, Yanhua.

Biochem Biophys Res Commun; 508(4): 1120-1125, 2019 01 22.

Artigo em Inglês | MEDLINE | ID: mdl-30553453

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