Pesquisa | Biblioteca Virtual em Saúde

1.

Dynamics of IFN-ß Responses During Respiratory Viral Infection: Insights for Therapeutic Strategies.

Watson, Alastair; Spalluto, C Mirella; McCrae, Christopher; Cellura, Doriana; Burke, Hannah; Cunoosamy, Danen; Freeman, Anna; Hicks, Alex; Hühn, Michael; Ostridge, Kristoffer; Staples, Karl J; Vaarala, Outi; Wilkinson, Tom.

Am J Respir Crit Care Med; 2019 Aug 28.

Artigo em Inglês | MEDLINE | ID: mdl-31461630

2.

Activation of group 2 innate lymphoid cells after allergen challenge in asthmatic patients.

Winkler, Carla; Hochdörfer, Thomas; Israelsson, Elisabeth; Hasselberg, Annemarie; Cavallin, Anders; Thörn, Kristofer; Muthas, Daniel; Shojaee, Shervin; Lüer, Katrin; Müller, Meike; Mjösberg, Jenny; Vaarala, Outi; Hohlfeld, Jens; Pardali, Katerina.

J Allergy Clin Immunol; 144(1): 61-69.e7, 2019 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-30731124

3.

IL-17-high asthma with features of a psoriasis immunophenotype.

Östling, Jörgen; van Geest, Marleen; Schofield, James P R; Jevnikar, Zala; Wilson, Susan; Ward, Jonathan; Lutter, Rene; Shaw, Dominick E; Bakke, Per S; Caruso, Massimo; Dahlen, Sven-Erik; Fowler, Stephen J; Horváth, Ildikó; Krug, Norbert; Montuschi, Paolo; Sanak, Marek; Sandström, Thomas; Sun, Kai; Pandis, Ioannis; Auffray, Charles; Sousa, Ana R; Guo, Yike; Adcock, Ian M; Howarth, Peter; Chung, Kian Fan; Bigler, Jeanette; Sterk, Peter J; Skipp, Paul J; Djukanovic, Ratko; Vaarala, Outi.

J Allergy Clin Immunol; 144(5): 1198-1213, 2019 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-30998987

4.

Gain-of-function CEBPE mutation causes noncanonical autoinflammatory inflammasomopathy.

Göös, Helka; Fogarty, Christopher L; Sahu, Biswajyoti; Plagnol, Vincent; Rajamäki, Kristiina; Nurmi, Katariina; Liu, Xiaonan; Einarsdottir, Elisabet; Jouppila, Annukka; Pettersson, Tom; Vihinen, Helena; Krjutskov, Kaarel; Saavalainen, Päivi; Järvinen, Asko; Muurinen, Mari; Greco, Dario; Scala, Giovanni; Curtis, James; Nordström, Dan; Flaumenhaft, Robert; Vaarala, Outi; Kovanen, Panu E; Keskitalo, Salla; Ranki, Annamari; Kere, Juha; Lehto, Markku; Notarangelo, Luigi D; Nejentsev, Sergey; Eklund, Kari K; Varjosalo, Markku; Taipale, Jussi; Seppänen, Mikko R J.

J Allergy Clin Immunol; 144(5): 1364-1376, 2019 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-31201888

5.

Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus.

Odqvist, Lina; Jevnikar, Zala; Riise, Rebecca; Öberg, Lisa; Rhedin, Magdalena; Leonard, Dag; Yrlid, Linda; Jackson, Sonya; Mattsson, Johan; Nanda, Sambit; Cohen, Philip; Knebel, Axel; Arthur, Simon; Thörn, Kristofer; Svenungsson, Elisabet; Jönsen, Andreas; Gunnarsson, Iva; Tandre, Karolina; Alexsson, Andrei; Kastbom, Alf; Rantapää-Dahlqvist, Solbritt; Eloranta, Maija-Leena; Syvänen, Ann-Christine; Bengtsson, Anders; Johansson, Patrik; Sandling, Johanna K; Sjöwall, Christopher; Rönnblom, Lars; Collins, Barry; Vaarala, Outi.

Ann Rheum Dis; 78(10): 1363-1370, 2019 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-31300459

6.

MEK inhibition drives anti-viral defence in RV but not RSV challenged human airway epithelial cells through AKT/p70S6K/4E-BP1 signalling.

Baturcam, Engin; Vollmer, Stefan; Schlüter, Holger; Maciewicz, Rose A; Kurian, Nisha; Vaarala, Outi; Ludwig, Stephan; Cunoosamy, Danen Mootoosamy.

Cell Commun Signal; 17(1): 78, 2019 Jul 18.

Artigo em Inglês | MEDLINE | ID: mdl-31319869

7.

Exposure to sewage water and the development of allergic manifestations in Finnish children.

Kujansuu, Eila; Kujansuu, Leena; Paassilta, Marita; Mustonen, Jukka; Vaarala, Outi.

Pediatr Allergy Immunol; 30(6): 598-603, 2019 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-31169932

8.

Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation.

Jevnikar, Zala; Östling, Jörgen; Ax, Elisabeth; Calvén, Jenny; Thörn, Kristofer; Israelsson, Elisabeth; Öberg, Lisa; Singhania, Akul; Lau, Laurie C K; Wilson, Susan J; Ward, Jonathan A; Chauhan, Anoop; Sousa, Ana R; De Meulder, Bertrand; Loza, Matthew J; Baribaud, Frédéric; Sterk, Peter J; Chung, Kian Fan; Sun, Kai; Guo, Yike; Adcock, Ian M; Payne, Debbie; Dahlen, Barbro; Chanez, Pascal; Shaw, Dominick E; Krug, Norbert; Hohlfeld, Jens M; Sandström, Thomas; Djukanovic, Ratko; James, Anna; Hinks, Timothy S C; Howarth, Peter H; Vaarala, Outi; van Geest, Marleen; Olsson, Henric.

J Allergy Clin Immunol; 2018 Jun 11.

Artigo em Inglês | MEDLINE | ID: mdl-29902480

9.

Lanosterol Synthase Regulates Human Rhinovirus Replication in Human Bronchial Epithelial Cells.

McCrae, Christopher; Dzgoev, Anatoly; Ståhlman, Marcus; Horndahl, Jenny; Svärd, Rebecka; Große, Arend; Großkopf, Theresia; Skujat, Mary-Ann; Williams, Nicola; Schubert, Steffen; Echeverri, Christophe; Jackson, Clive; Guedán, Anabel; Solari, Roberto; Vaarala, Outi; Kraan, Maarten; Rådinger, Madeleine.

Am J Respir Cell Mol Biol; 59(6): 713-722, 2018 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-30084659

10.

HLA-DPB1 and HLA class I confer risk of and protection from narcolepsy.

Ollila, Hanna M; Ravel, Jean-Marie; Han, Fang; Faraco, Juliette; Lin, Ling; Zheng, Xiuwen; Plazzi, Giuseppe; Dauvilliers, Yves; Pizza, Fabio; Hong, Seung-Chul; Jennum, Poul; Knudsen, Stine; Kornum, Birgitte R; Dong, Xiao Song; Yan, Han; Hong, Heeseung; Coquillard, Cristin; Mahlios, Joshua; Jolanki, Otto; Einen, Mali; Arnulf, Isabelle; Lavault, Sophie; Högl, Birgit; Frauscher, Birgit; Crowe, Catherine; Partinen, Markku; Huang, Yu Shu; Bourgin, Patrice; Vaarala, Outi; Désautels, Alex; Montplaisir, Jacques; Mack, Steven J; Mindrinos, Michael; Fernandez-Vina, Marcelo; Mignot, Emmanuel.

Am J Hum Genet; 96(1): 136-46, 2015 Jan 08.

Artigo em Inglês | MEDLINE | ID: mdl-25574827

11.

Avoidance of Cow's Milk-Based Formula for At-Risk Infants Does Not Reduce Development of Celiac Disease: A Randomized Controlled Trial.

Hyytinen, Mila; Savilahti, Erkki; Virtanen, Suvi M; Härkönen, Taina; Ilonen, Jorma; Luopajärvi, Kristiina; Uibo, Raivo; Vaarala, Outi; Åkerblom, Hans K; Knip, Mikael.

Gastroenterology; 153(4): 961-970.e3, 2017 10.

Artigo em Inglês | MEDLINE | ID: mdl-28687275

12.

Effect of Hydrolyzed Infant Formula vs Conventional Formula on Risk of Type 1 Diabetes: The TRIGR Randomized Clinical Trial.

Knip, Mikael; Åkerblom, Hans K; Al Taji, Eva; Becker, Dorothy; Bruining, Jan; Castano, Luis; Danne, Thomas; de Beaufort, Carine; Dosch, Hans-Michael; Dupre, John; Fraser, William D; Howard, Neville; Ilonen, Jorma; Konrad, Daniel; Kordonouri, Olga; Krischer, Jeffrey P; Lawson, Margaret L; Ludvigsson, Johnny; Madacsy, Laszlo; Mahon, Jeffrey L; Ormisson, Anne; Palmer, Jerry P; Pozzilli, Paolo; Savilahti, Erkki; Serrano-Rios, Manuel; Songini, Marco; Taback, Shayne; Vaarala, Outi; White, Neil H; Virtanen, Suvi M; Wasikowa, Renata.

JAMA; 319(1): 38-48, 2018 01 02.

Artigo em Inglês | MEDLINE | ID: mdl-29297078

13.

Fatty acid status in infancy is associated with the risk of type 1 diabetes-associated autoimmunity.

Niinistö, Sari; Takkinen, Hanna-Mari; Erlund, Iris; Ahonen, Suvi; Toppari, Jorma; Ilonen, Jorma; Veijola, Riitta; Knip, Mikael; Vaarala, Outi; Virtanen, Suvi M.

Diabetologia; 60(7): 1223-1233, 2017 07.

Artigo em Inglês | MEDLINE | ID: mdl-28474159

14.

Th1/Th17 plasticity is a marker of advanced ß cell autoimmunity and impaired glucose tolerance in humans.

Reinert-Hartwall, Linnea; Honkanen, Jarno; Salo, Harri M; Nieminen, Janne K; Luopajärvi, Kristiina; Härkönen, Taina; Veijola, Riitta; Simell, Olli; Ilonen, Jorma; Peet, Aleksandr; Tillmann, Vallo; Knip, Mikael; Vaarala, Outi.

J Immunol; 194(1): 68-75, 2015 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-25480564

15.

ω-3 fatty acids contribute to the asthma-protective effect of unprocessed cow's milk.

Brick, Tabea; Schober, Yvonne; Böcking, Christian; Pekkanen, Juha; Genuneit, Jon; Loss, Georg; Dalphin, Jean-Charles; Riedler, Josef; Lauener, Roger; Nockher, Wolfgang Andreas; Renz, Harald; Vaarala, Outi; Braun-Fahrländer, Charlotte; von Mutius, Erika; Ege, Markus Johannes; Pfefferle, Petra Ina.

J Allergy Clin Immunol; 137(6): 1699-1706.e13, 2016 06.

Artigo em Inglês | MEDLINE | ID: mdl-26792208

16.

Similar Antibody Levels in 3-Year-Old Children Vaccinated Against Measles, Mumps, and Rubella at the Age of 12 Months or 18 Months.

Kontio, Mia; Palmu, Arto A; Syrjänen, Ritva K; Lahdenkari, Mika; Ruokokoski, Esa; Davidkin, Irja; Vaarala, Outi; Melin, Merit.

J Infect Dis; 213(12): 2005-13, 2016 06 15.

Artigo em Inglês | MEDLINE | ID: mdl-26908733

17.

Consumption of unprocessed cow's milk protects infants from common respiratory infections.

Loss, Georg; Depner, Martin; Ulfman, Laurien H; van Neerven, R J Joost; Hose, Alexander J; Genuneit, Jon; Karvonen, Anne M; Hyvärinen, Anne; Kaulek, Vincent; Roduit, Caroline; Weber, Juliane; Lauener, Roger; Pfefferle, Petra Ina; Pekkanen, Juha; Vaarala, Outi; Dalphin, Jean-Charles; Riedler, Josef; Braun-Fahrländer, Charlotte; von Mutius, Erika; Ege, Markus J.

J Allergy Clin Immunol; 135(1): 56-62, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-25441645

18.

Whole-Genome Sequencing Identifies STAT4 as a Putative Susceptibility Gene in Classic Kaposi Sarcoma.

Aavikko, Mervi; Kaasinen, Eevi; Nieminen, Janne K; Byun, Minji; Donner, Iikki; Mancuso, Roberta; Ferrante, Pasquale; Clerici, Mario; Brambilla, Lucia; Tourlaki, Athanasia; Sarid, Ronit; Guttman-Yassky, Emma; Taipale, Minna; Morgunova, Ekaterina; Pekkonen, Pirita; Ojala, Päivi M; Pukkala, Eero; Casanova, Jean-Laurent; Vaarala, Outi; Vahteristo, Pia; Aaltonen, Lauri A.

J Infect Dis; 211(11): 1842-51, 2015 Jun 01.

Artigo em Inglês | MEDLINE | ID: mdl-25492914

19.

Autoantibodies against ganglioside GM3 are associated with narcolepsy-cataplexy developing after Pandemrix vaccination against 2009 pandemic H1N1 type influenza virus.

Saariaho, Anna-Helena; Vuorela, Arja; Freitag, Tobias L; Pizza, Fabio; Plazzi, Giuseppe; Partinen, Markku; Vaarala, Outi; Meri, Seppo.

J Autoimmun; 63: 68-75, 2015 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-26227560

20.

Infections in infants fed formula supplemented with bovine milk fat globule membranes.

Timby, Niklas; Hernell, Olle; Vaarala, Outi; Melin, Merit; Lönnerdal, Bo; Domellöf, Magnus.

J Pediatr Gastroenterol Nutr; 60(3): 384-9, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25714582

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