Pesquisa | Biblioteca Virtual em Saúde

1.

DNA methylation accumulation in gastric mucosa adjacent to cancer after Helicobacter pylori eradication.

Tahara, Sayumi; Tahara, Tomomitsu; Horiguchi, Noriyuki; Kato, Takema; Shinkai, Yasuko; Yamashita, Hiromi; Yamada, Hyuga; Kawamura, Tomohiko; Terada, Tsuyoshi; Okubo, Masaaki; Nagasaka, Mitsuo; Nakagawa, Yoshihito; Shibata, Tomoyuki; Yamada, Seiji; Urano, Makoto; Tsukamoto, Tetsuya; Kurahashi, Hiroki; Kuroda, Makoto; Ohmiya, Naoki.

Int J Cancer; 144(1): 80-88, 2019 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-29978464

2.

Cytokine expression profiles in cervical mucus from patients with cervical cancer and its precursor lesions.

Otani, Sayaka; Fujii, Takuma; Kukimoto, Iwao; Yamamoto, Naoki; Tsukamoto, Tetsuya; Ichikawa, Ryoko; Nishio, Eiji; Iwata, Aya.

Cytokine; 120: 210-219, 2019 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-31121496

3.

Gastric Mucosal Microarchitectures Associated with Irreversibility with Helicobacter pylori Eradication and Downregulation of Micro RNA (miR)-124a.

Tahara, Tomomitsu; Tahara, Sayumi; Horiguchi, Noriyuki; Kawamura, Tomohiko; Okubo, Masaaki; Nagasaka, Mitsuo; Nakagawa, Yoshihito; Shibata, Tomoyuki; Urano, Makoto; Tsukamoto, Tetsuya; Kuroda, Makoto; Ohmiya, Naoki.

Cancer Invest; 37(9): 417-426, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31483161

4.

Eradication of Helicobacter pylori Induces Immediate Regressive Changes in Early Gastric Adenocarcinomas.

Nakagawa, Mitsuru; Sakai, Yasuhiro; Kiriyama, Yuka; Tahara, Tomomitsu; Horiguchi, Noriyuki; Okabe, Asako; Tahara, Sayumi; Shibata, Tomoyuki; Ohmiya, Naoki; Kuroda, Makoto; Sugioka, Atsushi; Tsukamoto, Tetsuya.

Pathobiology; 86(2-3): 135-144, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-30879008

5.

An epilepsy-associated glioneuronal tumor with mixed morphology harboring FGFR1 mutation.

Yamada, Seiji; Nobusawa, Sumihito; Yamazaki, Tatsuya; Teranishi, Takao; Watanabe, Sadayoshi; Murayama, Kazuhiro; Ohba, Shigeo; Okabe, Asako; Sakurai, Kouhei; Urano, Makoto; Tsukamoto, Tetsuya; Yokoo, Hideaki; Hirose, Yuichi; Abe, Masato.

Pathol Int; 69(6): 372-377, 2019 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-31218776

6.

Endoscopic ultrasound-guided needle-based confocal laser endomicroscopy in gastrointestinal subepithelial lesions: Feasibility study.

Terada, Tsuyoshi; Tahara, Tomomitsu; Hashimoto, Senju; Horiguchi, Noriyuki; Funasaka, Kohei; Nagasaka, Mitsuo; Nakagawa, Yoshihito; Shibata, Tomoyuki; Yoshioka, Kentaro; Tsukamoto, Tetsuya; Kuroda, Makoto; Ohmiya, Naoki.

Dig Endosc; 2019 Sep 28.

Artigo em Inglês | MEDLINE | ID: mdl-31562825

7.

18ß-glycyrrhetinic acid inhibited mitochondrial energy metabolism and gastric carcinogenesis through methylation regulated TLR2 signaling pathway.

Cao, Donghui; Wu, Yanhua; Jia, Zhifang; Zhao, Dan; Zhang, Yangyu; Zhou, Tianyu; Wu, Menghui; Zhang, Houjun; Tsukamoto, Tetsuya; Oshima, Masanobu; Jiang, Jing; Cao, Xueyuan.

Carcinogenesis; 2018 Oct 26.

Artigo em Inglês | MEDLINE | ID: mdl-30364936

8.

Established gastric cancer cell lines transplantable into C57BL/6 mice show fibroblast growth factor receptor 4 promotion of tumor growth.

Yamamoto, Masami; Nomura, Sachiyo; Hosoi, Akihiro; Nagaoka, Koji; Iino, Tamaki; Yasuda, Tomohiko; Saito, Tomoko; Matsushita, Hirokazu; Uchida, Eiji; Seto, Yasuyuki; Goldenring, James R; Kakimi, Kazuhiko; Tatematsu, Masae; Tsukamoto, Tetsuya.

Cancer Sci; 109(5): 1480-1492, 2018 May.

Artigo em Inglês | MEDLINE | ID: mdl-29532565

9.

Development of a Comorbidity Index to Identify Patients With Small Bowel Bleeding at Risk for Rebleeding and Small Bowel Vascular Diseases.

Ohmiya, Naoki; Nakamura, Masanao; Osaki, Hayato; Yamada, Hyuga; Tahara, Tomomitsu; Nagasaka, Mitsuo; Nakagawa, Yoshihito; Shibata, Tomoyuki; Tsukamoto, Tetsuya; Kuroda, Makoto.

Clin Gastroenterol Hepatol; 2018 Aug 18.

Artigo em Inglês | MEDLINE | ID: mdl-30130626

10.

In vivo diagnosis of early-stage gastric cancer found after Helicobacter pylori eradication using probe-based confocal laser endomicroscopy.

Horiguchi, Noriyuki; Tahara, Tomomitsu; Yamada, Hyuga; Yoshida, Dai; Okubo, Masaaki; Nagasaka, Mitsuo; Nakagawa, Yoshihito; Shibata, Tomoyuki; Tsukamoto, Tetsuya; Kuroda, Makoto; Ohmiya, Naoki.

Dig Endosc; 30(2): 219-227, 2018 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-28731617

11.

Practical application of 3-substituted-2,6-difluoropyridines in drug discovery: Facile synthesis of novel protein kinase C theta inhibitors.

Katoh, Taisuke; Tomata, Yoshihide; Setoh, Masaki; Sasaki, Satoshi; Takai, Takafumi; Yoshitomi, Yayoi; Yukawa, Tomoya; Nakagawa, Hideyuki; Fukumoto, Shoji; Tsukamoto, Tetsuya; Nakada, Yoshihisa.

Bioorg Med Chem Lett; 27(11): 2497-2501, 2017 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-28400232

12.

Impact of acute fat mobilisation on the pharmacokinetics of the highly fat distributed compound TAK-357, investigated by physiologically based pharmacokinetic (PBPK) modeling and simulation.

Goto, Akihiko; Tagawa, Yoshihiko; Moriya, Yuu; Sato, Sho; Furukawa, Yoshiyuki; Wakabayashi, Takeshi; Tsukamoto, Tetsuya; DeJongh, Joost; van Steeg, Tamara J; Moriwaki, Toshiya; Asahi, Satoru.

Biopharm Drug Dispos; 38(6): 373-380, 2017 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-28256717

13.

Influence of body composition on disposition of the highly fat distributed compound as analysed by physiologically based pharmacokinetic (PBPK) modeling and simulation.

Goto, Akihiko; Tagawa, Yoshihiko; Moriya, Yuu; Sato, Sho; Yamamoto, Masami; Wakabayashi, Takeshi; Tsukamoto, Tetsuya; DeJongh, Joost; van Steeg, Tamara J; Moriwaki, Toshiya; Asahi, Satoru.

Biopharm Drug Dispos; 38(9): 543-552, 2017 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-28948605

14.

Usefulness of confocal laser endomicroscopy to diagnose ulcerative colitis-associated neoplasia.

Ohmiya, Naoki; Horiguchi, Noriyuki; Tahara, Tomomitsu; Yoshida, Dai; Yamada, Hyuga; Nagasaka, Mitsuo; Nakagawa, Yoshihito; Shibata, Tomoyuki; Tsukamoto, Tetsuya; Kuroda, Makoto.

Dig Endosc; 29(5): 626-633, 2017 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-28244237

15.

Prevention of Gastric Cancer: Eradication of Helicobacter Pylori and Beyond.

Tsukamoto, Tetsuya; Nakagawa, Mitsuru; Kiriyama, Yuka; Toyoda, Takeshi; Cao, Xueyuan.

Int J Mol Sci; 18(8)2017 Aug 03.

Artigo em Inglês | MEDLINE | ID: mdl-28771198

16.

Anti-Inflammatory Effects of Capsaicin and Piperine on Helicobacter pylori-Induced Chronic Gastritis in Mongolian Gerbils.

Toyoda, Takeshi; Shi, Liang; Takasu, Shinji; Cho, Young-Man; Kiriyama, Yuka; Nishikawa, Akiyoshi; Ogawa, Kumiko; Tatematsu, Masae; Tsukamoto, Tetsuya.

Helicobacter; 21(2): 131-42, 2016 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-26140520

17.

Discovery of novel 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine derivatives as Î³-secretase modulators (Part 2).

Takai, Takafumi; Koike, Tatsuki; Nakamura, Minoru; Kajita, Yuichi; Yamashita, Toshiro; Taya, Naohiro; Tsukamoto, Tetsuya; Watanabe, Tomomichi; Murakami, Koji; Igari, Tomoko; Kamata, Makoto.

Bioorg Med Chem; 24(14): 3192-206, 2016 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-27255179

18.

Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-ones as potent and selective PKCÎ¸ inhibitors.

Katoh, Taisuke; Takai, Takafumi; Yukawa, Takafumi; Tsukamoto, Tetsuya; Watanabe, Etsurou; Mototani, Hideyuki; Arita, Takeo; Hayashi, Hiroki; Nakagawa, Hideyuki; Klein, Michael G; Zou, Hua; Sang, Bi-Ching; Snell, Gyorgy; Nakada, Yoshihisa.

Bioorg Med Chem; 24(11): 2466-75, 2016 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-27117263

19.

Design, synthesis, and biological evaluation of a novel series of peripheral-selective noradrenaline reuptake inhibitors-Part 2.

Yukawa, Tomoya; Fujimori, Ikuo; Kamei, Taku; Nakada, Yoshihisa; Sakauchi, Nobuki; Yamada, Masami; Ohba, Yusuke; Ueno, Hiroyuki; Takiguchi, Maiko; Kuno, Masako; Kamo, Izumi; Nakagawa, Hideyuki; Fujioka, Yasushi; Igari, Tomoko; Ishichi, Yuji; Tsukamoto, Tetsuya.

Bioorg Med Chem; 24(14): 3207-17, 2016 07 15.

Artigo em Inglês | MEDLINE | ID: mdl-27255177

20.

Design, synthesis, and biological evaluation of a novel series of peripheral-selective noradrenaline reuptake inhibitors - Part 3.

Yukawa, Tomoya; Nakada, Yoshihisa; Sakauchi, Nobuki; Kamei, Taku; Yamada, Masami; Ohba, Yusuke; Fujimori, Ikuo; Ueno, Hiroyuki; Takiguchi, Maiko; Kuno, Masako; Kamo, Izumi; Nakagawa, Hideyuki; Fujioka, Yasushi; Igari, Tomoko; Ishichi, Yuji; Tsukamoto, Tetsuya.

Bioorg Med Chem; 24(16): 3716-26, 2016 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-27325446

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