Pesquisa | Biblioteca Virtual em Saúde

1.

Suppressing the CDC37 cochaperone in hepatocellular carcinoma cells inhibits cell cycle progression and cell growth.

Wang, Zhanhui; Wei, Wei; Sun, Chris K; Chua, Mei-Sze; So, Samuel.

Liver Int; 35(4): 1403-15, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25098386

2.

The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors.

Willingham, Stephen B; Volkmer, Jens-Peter; Gentles, Andrew J; Sahoo, Debashis; Dalerba, Piero; Mitra, Siddhartha S; Wang, Jian; Contreras-Trujillo, Humberto; Martin, Robin; Cohen, Justin D; Lovelace, Patricia; Scheeren, Ferenc A; Chao, Mark P; Weiskopf, Kipp; Tang, Chad; Volkmer, Anne Kathrin; Naik, Tejaswitha J; Storm, Theresa A; Mosley, Adriane R; Edris, Badreddin; Schmid, Seraina M; Sun, Chris K; Chua, Mei-Sze; Murillo, Oihana; Rajendran, Pradeep; Cha, Adriel C; Chin, Robert K; Kim, Dongkyoon; Adorno, Maddalena; Raveh, Tal; Tseng, Diane; Jaiswal, Siddhartha; Enger, Per Øyvind; Steinberg, Gary K; Li, Gordon; So, Samuel K; Majeti, Ravindra; Harsh, Griffith R; van de Rijn, Matt; Teng, Nelson N H; Sunwoo, John B; Alizadeh, Ash A; Clarke, Michael F; Weissman, Irving L.

Proc Natl Acad Sci U S A; 109(17): 6662-7, 2012 Apr 24.

Artigo em Inglês | MEDLINE | ID: mdl-22451913

3.

Suppression of liver tumor growth and metastasis by adiponectin in nude mice through inhibition of tumor angiogenesis and downregulation of Rho kinase/IFN-inducible protein 10/matrix metalloproteinase 9 signaling.

Man, Kwan; Ng, Kevin T P; Xu, Aimin; Cheng, Qiao; Lo, Chung Mau; Xiao, Jiang Wei; Sun, Bai Shun; Lim, Zophia X H; Cheung, Jerry S; Wu, Ed X; Sun, Chris K W; Poon, Ronnie T P; Fan, Sheung Tat.

Clin Cancer Res; 16(3): 967-77, 2010 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-20103676

4.

Suppression of tumorigenesis and metastasis of hepatocellular carcinoma by shRNA interference targeting on homeoprotein Six1.

Ng, Kevin T P; Lee, Terence K W; Cheng, Qiao; Wo, Jana Y H; Sun, Chris K W; Guo, Dong-Yong; Lim, Zophia X; Lo, Chung-Mau; Poon, Ronnie T P; Fan, Sheung-Tat; Man, Kwan.

Int J Cancer; 127(4): 859-72, 2010 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-20013809

5.

Molecular signature linked to acute phase injury and tumor invasiveness in small-for-size liver grafts.

Man, Kwan; Shih, Kendrick Co; Ng, Kevin T P; Xiao, Jiang Wei; Guo, Dong Yong; Sun, Chris K W; Lim, Zophia X H; Cheng, Qiao; Liu, Yan; Fan, Sheung Tat; Lo, Chung Mau.

Ann Surg; 251(6): 1154-61, 2010 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-20485145

6.

Proline-rich tyrosine kinase 2 (Pyk2) promotes proliferation and invasiveness of hepatocellular carcinoma cells through c-Src/ERK activation.

Sun, Chris K; Man, Kwan; Ng, Kevin T; Ho, Joanna W; Lim, Zophia X; Cheng, Qiao; Lo, Chung-Mau; Poon, Ronnie T; Fan, Sheung-Tat.

Carcinogenesis; 29(11): 2096-105, 2008 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-18765415

7.

The significance of acute phase small-for-size graft injury on tumor growth and invasiveness after liver transplantation.

Man, Kwan; Lo, Chung Mau; Xiao, Jiang Wei; Ng, Kevin T; Sun, Bai Shun; Ng, Irene O; Cheng, Qiao; Sun, Chris K; Fan, Sheung Tat.

Ann Surg; 247(6): 1049-57, 2008 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-18520234

8.

Marked suppression of tumor growth by FTY720 in a rat liver tumor model: the significance of down-regulation of cell survival Akt pathway.

Ng, Kevin T; Man, Kwan; Ho, Joanna W; Sun, Chris K; Lee, Terence K; Zhao, Yi; Lo, Chung Mau; Poon, Ronnie T; Fan, Sheung Tat.

Int J Oncol; 30(2): 375-80, 2007 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-17203219

9.

FTY720: a promising agent for treatment of metastatic hepatocellular carcinoma.

Lee, Terence K; Man, Kwan; Ho, Joanna W; Wang, Xiang Hong; Poon, Ronnie T P; Xu, Yang; Ng, Kevin T; Chu, Alan C; Sun, Chris K; Ng, Irene O; Sun, Hui Chuan; Tang, Zao You; Xu, Ray; Fan, Sheung Tat.

Clin Cancer Res; 11(23): 8458-66, 2005 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-16322309

10.

Effects of a novel immunomodulating agent, FTY720, on tumor growth and angiogenesis in hepatocellular carcinoma.

Ho, Joanna W Y; Man, Kwan; Sun, Chris K; Lee, Terence K; Poon, Ronnie T P; Fan, Sheung Tat.

Mol Cancer Ther; 4(9): 1430-8, 2005 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-16170036

11.

Clinicopathological and prognostic implications of endoglin (CD105) expression in hepatocellular carcinoma and its adjacent non-tumorous liver.

Ho, Joanna-W; Poon, Ronnie-T; Sun, Chris-K; Xue, Wei-Cheng; Fan, Sheung-Tat.

World J Gastroenterol; 11(2): 176-81, 2005 Jan 14.

Artigo em Inglês | MEDLINE | ID: mdl-15633211

12.

Imaging of hepatocellular carcinoma patient-derived xenografts using 89Zr-labeled anti-glypican-3 monoclonal antibody.

Yang, Xiaoyang; Liu, Hongguang; Sun, Chris K; Natarajan, Arutselvan; Hu, Xiang; Wang, Xiaolin; Allegretta, Mark; Guttmann, Ronald D; Gambhir, Sanjiv S; Chua, Mei-Sze; Cheng, Zhen; So, Samuel K.

Biomaterials; 35(25): 6964-71, 2014 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-24836949

13.

Suppression of glypican 3 inhibits growth of hepatocellular carcinoma cells through up-regulation of TGF-ß2.

Sun, Chris K; Chua, Mei-Sze; He, Jing; So, Samuel K.

Neoplasia; 13(8): 735-47, 2011 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-21847365

14.

Proline-rich tyrosine kinase 2 (Pyk2) promotes cell motility of hepatocellular carcinoma through induction of epithelial to mesenchymal transition.

Sun, Chris K; Ng, Kevin T; Lim, Zophia X; Cheng, Qiao; Lo, Chung Mau; Poon, Ronnie T; Man, Kwan; Wong, Nathalie; Fan, Sheung Tat.

PLoS One; 6(4): e18878, 2011 Apr 20.

Artigo em Inglês | MEDLINE | ID: mdl-21533080

15.

The role of proline rich tyrosine kinase 2 (Pyk2) on cisplatin resistance in hepatocellular carcinoma.

Geng, Wei; Ng, Kevin T P; Sun, Chris K W; Yau, Wing Lung; Liu, Xiao Bing; Cheng, Qiao; Poon, Ronnie T P; Lo, Chung Mau; Man, Kwan; Fan, Sheung Tat.

PLoS One; 6(11): e27362, 2011.

Artigo em Inglês | MEDLINE | ID: mdl-22096562

16.

Ischemia-reperfusion of small liver remnant promotes liver tumor growth and metastases--activation of cell invasion and migration pathways.

Man, Kwan; Ng, Kevin T; Lo, Chung Mau; Ho, Joanna W; Sun, Bai Shun; Sun, Chris K; Lee, Terence K; Poon, Ronnie T P; Fan, Sheung Tat.

Liver Transpl; 13(12): 1669-77, 2007 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-18044786

17.

Significance of circulating endothelial progenitor cells in hepatocellular carcinoma.

Ho, Joanna W Y; Pang, Roberta W C; Lau, Cecilia; Sun, Chris K; Yu, Wan Ching; Fan, Sheung Tat; Poon, Ronnie T P.

Hepatology; 44(4): 836-43, 2006 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-17006919

18.

The influence of phosphatidylinositol 3-kinase/Akt pathway on the ischemic injury during rat liver graft preservation.

Li, Xian Liang; Man, Kwan; Ng, Kevin T; Sun, Chris K; Lo, Chung Mau; Fan, Sheung Tat.

Am J Transplant; 5(6): 1264-75, 2005 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-15888030

19.

FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers.

Man, Kwan; Ng, Kevin T; Lee, Terence K; Lo, Chung Mau; Sun, Chris K; Li, Xian Liang; Zhao, Yi; Ho, Joanna W; Fan, Sheung Tat.

Am J Transplant; 5(1): 40-9, 2005 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-15636610

20.

Significance of the Rac signaling pathway in HCC cell motility: implications for a new therapeutic target.

Lee, Terence K; Man, Kwan; Ho, Joanna W; Wang, Xiang Hong; Poon, Ronnie T; Sun, Chris K; Ng, Kevin T; Ng, Irene O; Xu, Ray; Fan, Sheung Tat.

Carcinogenesis; 26(3): 681-7, 2005 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-15604094

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