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1.

The TKI-Free Duration after a First Discontinuation Attempt That Failed in CP CML Patients Is a Predictive Factor of TKI-Free Remission after a Second Attempt.

Legros, Laurence; Nicolini, Franck E; Etienne, Gabriel; Rousselot, Philippe; Rea, Delphine; Giraudier, Stephane; Guerci, Agnès; Huguet, Francoise; Gardembas, Martine; Ianotto, Jean-Christophe; Escoffre-Barbe, Martine; Coiteux, Valerie; Varet, Bruno; Morisset, Stephane; Mahon, Francois-Xavier.

Blood; 134(Supplement_1): 28, 2019 Nov 13.

Artigo em Inglês | MEDLINE | ID: mdl-31723981

2.

Prognostication of Molecular Relapses after Dasatinib or Nilotinib Discontinuation in Chronic Myeloid Leukemia (CML): A FI-LMC STOP 2G-TKI Study Update.

Rea, Delphine; Nicolini, Franck E; Tulliez, Michel; Rousselot, Philippe; Gardembas, Martine; Etienne, Gabriel; Guilhot, Francois; Guilhot, Joelle; Guerci, Agnès; Escoffre-Barbe, Martine; Legros, Laurence; Villemagne, Bruno; Guillerm, Gaëlle; Noel, Marie-Pierre; Coiteux, Valerie; Pignon, Jean-Michel; Mahon, Francois-Xavier.

Blood; 134(Supplement_1): 30, 2019 Nov 13.

Artigo em Inglês | MEDLINE | ID: mdl-31724000

3.

Ponatinib efficacy and safety in Philadelphia chromosome-positive leukemia: final 5-year results of the phase 2 PACE trial.

Cortes, Jorge E; Kim, Dong-Wook; Pinilla-Ibarz, Javier; le Coutre, Philipp D; Paquette, Ronald; Chuah, Charles; Nicolini, Franck E; Apperley, Jane F; Khoury, H Jean; Talpaz, Moshe; DeAngelo, Daniel J; Abruzzese, Elisabetta; Rea, Delphine; Baccarani, Michele; Müller, Martin C; Gambacorti-Passerini, Carlo; Lustgarten, Stephanie; Rivera, Victor M; Haluska, Frank G; Guilhot, François; Deininger, Michael W; Hochhaus, Andreas; Hughes, Timothy P; Shah, Neil P; Kantarjian, Hagop M.

Blood; 132(4): 393-404, 2018 Jul 26.

Artigo em Inglês | MEDLINE | ID: mdl-29567798

4.

Evaluation of Residual Disease and TKI Duration Are Critical Predictive Factors for Molecular Recurrence after Stopping Imatinib First-line in Chronic Phase CML Patients.

Nicolini, Franck Emmanuel; Dulucq, Stéphanie; Boureau, Lisa; Cony-Makhoul, Pascale; Charbonnier, Aude; Escoffre-Barbe, Martine; Rigal-Huguet, Françoise; Coiteux, Valérie; Varet, Bruno; Dubruille, Viviane; Lenain, Pascal; Rousselot, Philippe; Rea, Delphine; Guerci-Bresler, Agnès; Legros, Laurence; Liu, Jixing; Gardembas, Martine; Ianotto, Jean-Christophe; Turlure, Pascal; Johnson-Ansah, Hyacinthe; Martiniuc, Juliana; Jardel, Henry; Joly, Bertrand; Zunic, Patricia; Henni, Tawfiq; Villemagne, Bruno; Berger, Marc G; Cayssials, Emilie; Guilhot, François; Larosa, Fabrice; Guilhot, Joëlle; Etienne, Gabriel; Mahon, François-Xavier.

Clin Cancer Res; 25(22): 6606-6613, 2019 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-31292142

5.

Longer treatment duration and history of osteoarticular symptoms predispose to tyrosine kinase inhibitor withdrawal syndrome.

Berger, Marc G; Pereira, Bruno; Rousselot, Philippe; Cony-Makhoul, Pascale; Gardembas, Martine; Legros, Laurence; Escoffre-Barbe, Martine; Nicolini, Franck-Emmanuel; Saugues, Sandrine; Lambert, Céline; Réa, Delphine; Guerci-Bresler, Agnès; Giraudier, Stéphane; Guilhot, Joëlle; Saussele, Susanne; Mahon, François-Xavier.

Br J Haematol; 187(3): 337-346, 2019 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-31271217

6.

Discontinuation of dasatinib or nilotinib in chronic myeloid leukemia: interim analysis of the STOP 2G-TKI study.

Rea, Delphine; Nicolini, Franck E; Tulliez, Michel; Guilhot, François; Guilhot, Joelle; Guerci-Bresler, Agnès; Gardembas, Martine; Coiteux, Valérie; Guillerm, Gaelle; Legros, Laurence; Etienne, Gabriel; Pignon, Jean-Michel; Villemagne, Bruno; Escoffre-Barbe, Martine; Ianotto, Jean-Christophe; Charbonnier, Aude; Johnson-Ansah, Hyacinthe; Noel, Marie-Pierre; Rousselot, Philippe; Mahon, François-Xavier.

Blood; 129(7): 846-854, 2017 02 16.

Artigo em Inglês | MEDLINE | ID: mdl-27932374

7.

Poor prognosis of chromosome 7 clonal aberrations in Philadelphia-negative metaphases and relevance of potential underlying myelodysplastic features in chronic myeloid leukemia.

Bidet, Audrey; Dulucq, Stéphanie; Smol, Thomas; Marceau-Renaut, Alice; Morisset, Stéphane; Coiteux, Valérie; Noël-Walter, Marie-Pierre; Nicolini, Franck-Emmanuel; Tigaud, Isabelle; Luquet, Isabelle; Struski, Stéphanie; Gaillard, Baptiste; Penther, Dominique; Tondeur, Sylvie; Nadal, Nathalie; Hermet, Eric; Véronèse, Lauren; Réa, Delphine; Gervais, Carine; Theisen, Olivier; Terré, Christine; Cony-Makhoul, Pascale; Lefebvre, Christine; Gaillard, Jean-Baptiste; Radford, Isabelle; Vervaeke, Anne-Laure; Barin, Carole; Chapiro, Elise; Nguyen-Khac, Florence; Etienne, Gabriel; Preudhomme, Claude; Mahon, François Xavier; Roche-Lestienne, Catherine.

Haematologica; 104(6): 1150-1155, 2019 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-30573507

8.

Discontinuation of tyrosine kinase inhibitors in chronic myeloid leukemia: Recommendations for clinical practice from the French Chronic Myeloid Leukemia Study Group.

Rea, Delphine; Ame, Shanti; Berger, Marc; Cayuela, Jean-Michel; Charbonnier, Aude; Coiteux, Valérie; Cony-Makhoul, Pascale; Dubruille, Viviane; Dulucq, Stéphanie; Etienne, Gabriel; Legros, Laurence; Nicolini, Franck; Roche-Lestienne, Catherine; Escoffre-Barbe, Martine; Gardembas, Martine; Guerci-Bresler, Agnès; Johnson-Ansah, Hyacinthe; Rigal-Huguet, Françoise; Rousselot, Philippe; Mahon, François-Xavier.

Cancer; 124(14): 2956-2963, 2018 Jul 15.

Artigo em Inglês | MEDLINE | ID: mdl-29723417

9.

How I manage relapse of chronic myeloid leukaemia after stopping tyrosine kinase inhibitor therapy.

Rea, Delphine; Mahon, François-Xavier.

Br J Haematol; 180(1): 24-32, 2018 01.

Artigo em Inglês | MEDLINE | ID: mdl-29048128

10.

Incidence, outcomes, and risk factors of pleural effusion in patients receiving dasatinib therapy for Philadelphia chromosome-positive leukemia.

Hughes, Timothy P; Laneuville, Pierre; Rousselot, Philippe; Snyder, David S; Rea, Delphine; Shah, Neil P; Paar, David; Abruzzese, Elisabetta; Hochhaus, Andreas; Lipton, Jeffrey H; Cortes, Jorge E.

Haematologica; 2018 Aug 09.

Artigo em Inglês | MEDLINE | ID: mdl-30093398

11.

Treatment-free remission with first- and second-generation tyrosine kinase inhibitors.

Cortes, Jorge; Rea, Delphine; Lipton, Jeffrey H.

Am J Hematol; 2018 Nov 05.

Artigo em Inglês | MEDLINE | ID: mdl-30394563

12.

Second tyrosine kinase inhibitor discontinuation attempt in patients with chronic myeloid leukemia.

Legros, Laurence; Nicolini, Franck E; Etienne, Gabriel; Rousselot, Philippe; Rea, Delphine; Giraudier, Stéphane; Guerci-Bresler, Agnès; Huguet, Françoise; Gardembas, Martine; Escoffre, Martine; Ianotto, Jean-Christophe; Noël, Marie-Pierre; Varet, Bruno R; Pagliardini, Thomas; Touitou, Irit; Morisset, Stéphane; Mahon, Francois-Xavier.

Cancer; 123(22): 4403-4410, 2017 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-28743166

13.

Vascular safety issues in CML patients treated with BCR/ABL1 kinase inhibitors.

Valent, Peter; Hadzijusufovic, Emir; Schernthaner, Gerit-Holger; Wolf, Dominik; Rea, Delphine; le Coutre, Philipp.

Blood; 125(6): 901-6, 2015 Feb 05.

Artigo em Inglês | MEDLINE | ID: mdl-25525119

14.

Recurrent ETNK1 mutations in atypical chronic myeloid leukemia.

Gambacorti-Passerini, Carlo B; Donadoni, Carla; Parmiani, Andrea; Pirola, Alessandra; Redaelli, Sara; Signore, Giovanni; Piazza, Vincenzo; Malcovati, Luca; Fontana, Diletta; Spinelli, Roberta; Magistroni, Vera; Gaipa, Giuseppe; Peronaci, Marco; Morotti, Alessandro; Panuzzo, Cristina; Saglio, Giuseppe; Usala, Emilio; Kim, Dong-Wook; Rea, Delphine; Zervakis, Konstantinos; Viniou, Nora; Symeonidis, Argiris; Becker, Heiko; Boultwood, Jacqueline; Campiotti, Leonardo; Carrabba, Matteo; Elli, Elena; Bignell, Graham R; Papaemmanuil, Elli; Campbell, Peter J; Cazzola, Mario; Piazza, Rocco.

Blood; 125(3): 499-503, 2015 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-25343957

15.

Natural killer-cell counts are associated with molecular relapse-free survival after imatinib discontinuation in chronic myeloid leukemia: the IMMUNOSTIM study.

Rea, Delphine; Henry, Guylaine; Khaznadar, Zena; Etienne, Gabriel; Guilhot, François; Nicolini, Franck; Guilhot, Joelle; Rousselot, Philippe; Huguet, Françoise; Legros, Laurence; Gardembas, Martine; Dubruille, Viviane; Guerci-Bresler, Agnès; Charbonnier, Aude; Maloisel, Frédéric; Ianotto, Jean-Christophe; Villemagne, Bruno; Mahon, François-Xavier; Moins-Teisserenc, Hélène; Dulphy, Nicolas; Toubert, Antoine.

Haematologica; 102(8): 1368-1377, 2017 08.

Artigo em Inglês | MEDLINE | ID: mdl-28522576

16.

Deep molecular responses achieved in patients with CML-CP who are switched to nilotinib after long-term imatinib.

Hughes, Timothy P; Lipton, Jeffrey H; Spector, Nelson; Cervantes, Francisco; Pasquini, Ricardo; Clementino, Nelma Cristina D; Dorlhiac Llacer, Pedro Enrique; Schwarer, Anthony P; Mahon, Francois-Xavier; Rea, Delphine; Branford, Susan; Purkayastha, Das; Collins, LaTonya; Szczudlo, Tomasz; Leber, Brian.

Blood; 124(5): 729-36, 2014 Jul 31.

Artigo em Inglês | MEDLINE | ID: mdl-24948656

17.

Dasatinib in imatinib-resistant or -intolerant chronic-phase, chronic myeloid leukemia patients: 7-year follow-up of study CA180-034.

Shah, Neil P; Rousselot, Philippe; Schiffer, Charles; Rea, Delphine; Cortes, Jorge E; Milone, Jorge; Mohamed, Hesham; Healey, Diane; Kantarjian, Hagop; Hochhaus, Andreas; Saglio, Giuseppe.

Am J Hematol; 91(9): 869-74, 2016 09.

Artigo em Inglês | MEDLINE | ID: mdl-27192969

18.

Final analysis of the efficacy and safety of omacetaxine mepesuccinate in patients with chronic- or accelerated-phase chronic myeloid leukemia: Results with 24 months of follow-up.

Cortes, Jorge E; Kantarjian, Hagop M; Rea, Delphine; Wetzler, Meir; Lipton, Jeffrey H; Akard, Luke; Khoury, H Jean; Michallet, Mauricette; Guerci-Bresler, Agnès; Chuah, Charles; Hellmann, Andrzej; Digumarti, Raghunadharao; Parikh, Purvish M; Legros, Laurence; Warzocha, Krzysztof; Baccarani, Michele; Li, Elizabeth; Munteanu, Mihaela; Nicolini, Franck E.

Cancer; 121(10): 1637-44, 2015 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-25586015

19.

Management of adverse events associated with tyrosine kinase inhibitors in chronic myeloid leukemia.

Rea, Delphine.

Ann Hematol; 94 Suppl 2: S149-58, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-25814081

20.

Rapid onset of peripheral artery disease in a chronic myeloid leukemia patient without prior arterial disorder: direct relationship with nilotinib exposure and clinical outcome.

Mirault, Tristan; Rea, Delphine; Azarine, Arshid; Messas, Emmanuel.

Eur J Haematol; 94(4): 363-7, 2015 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-24797802

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