Pesquisa | Biblioteca Virtual em Saúde

1.

Proteogenomics connects somatic mutations to signalling in breast cancer.

Mertins, Philipp; Mani, D R; Ruggles, Kelly V; Gillette, Michael A; Clauser, Karl R; Wang, Pei; Wang, Xianlong; Qiao, Jana W; Cao, Song; Petralia, Francesca; Kawaler, Emily; Mundt, Filip; Krug, Karsten; Tu, Zhidong; Lei, Jonathan T; Gatza, Michael L; Wilkerson, Matthew; Perou, Charles M; Yellapantula, Venkata; Huang, Kuan-lin; Lin, Chenwei; McLellan, Michael D; Yan, Ping; Davies, Sherri R; Townsend, R Reid; Skates, Steven J; Wang, Jing; Zhang, Bing; Kinsinger, Christopher R; Mesri, Mehdi; Rodriguez, Henry; Ding, Li; Paulovich, Amanda G; Fenyö, David; Ellis, Matthew J; Carr, Steven A.

Nature; 534(7605): 55-62, 2016 06 02.

Artigo em Inglês | MEDLINE | ID: mdl-27251275

2.

Integrative Proteo-genomic Analysis to Construct CNA-protein Regulatory Map in Breast and Ovarian Tumors.

Ma, Weiping; Chen, Lin S; Özbek, Umut; Han, Sung Won; Lin, Chenwei; Paulovich, Amanda G; Zhong, Hua; Wang, Pei.

Mol Cell Proteomics; 18(8 suppl 1): S66-S81, 2019 08 09.

Artigo em Inglês | MEDLINE | ID: mdl-31281117

3.

Proteome Profiling Outperforms Transcriptome Profiling for Coexpression Based Gene Function Prediction.

Wang, Jing; Ma, Zihao; Carr, Steven A; Mertins, Philipp; Zhang, Hui; Zhang, Zhen; Chan, Daniel W; Ellis, Matthew J C; Townsend, R Reid; Smith, Richard D; McDermott, Jason E; Chen, Xian; Paulovich, Amanda G; Boja, Emily S; Mesri, Mehdi; Kinsinger, Christopher R; Rodriguez, Henry; Rodland, Karin D; Liebler, Daniel C; Zhang, Bing.

Mol Cell Proteomics; 16(1): 121-134, 2017 01.

Artigo em Inglês | MEDLINE | ID: mdl-27836980

4.

pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry.

Jones, Gemma N; Rooney, Claire; Griffin, Nicola; Roudier, Martine; Young, Lucy A; Garcia-Trinidad, Antonio; Hughes, Gareth D; Whiteaker, Jeffrey R; Wilson, Zena; Odedra, Rajesh; Zhao, Lei; Ivey, Richard G; Howat, William J; Harrington, Elizabeth A; Barrett, J Carl; Ramos-Montoya, Antonio; Lau, Alan; Paulovich, Amanda G; Cadogan, Elaine B; Pierce, Andrew J.

Br J Cancer; 119(10): 1233-1243, 2018 11.

Artigo em Inglês | MEDLINE | ID: mdl-30385821

5.

Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation.

Marcon, Edyta; Jain, Harshika; Bhattacharya, Anandi; Guo, Hongbo; Phanse, Sadhna; Pu, Shuye; Byram, Gregory; Collins, Ben C; Dowdell, Evan; Fenner, Maria; Guo, Xinghua; Hutchinson, Ashley; Kennedy, Jacob J; Krastins, Bryan; Larsen, Brett; Lin, Zhen-Yuan; Lopez, Mary F; Loppnau, Peter; Miersch, Shane; Nguyen, Tin; Olsen, Jonathan B; Paduch, Marcin; Ravichandran, Mani; Seitova, Alma; Vadali, Gouri; Vogelsang, Maryann S; Whiteaker, Jeffrey R; Zhong, Guoqing; Zhong, Nan; Zhao, Lei; Aebersold, Ruedi; Arrowsmith, Cheryl H; Emili, Andrew; Frappier, Lori; Gingras, Anne-Claude; Gstaiger, Matthias; Paulovich, Amanda G; Koide, Shohei; Kossiakoff, Anthony A; Sidhu, Sachdev S; Wodak, Shoshana J; Gräslund, Susanne; Greenblatt, Jack F; Edwards, Aled M.

Nat Methods; 12(8): 725-31, 2015 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-26121405

6.

Immobilized Metal Affinity Chromatography Coupled to Multiple Reaction Monitoring Enables Reproducible Quantification of Phospho-signaling.

Kennedy, Jacob J; Yan, Ping; Zhao, Lei; Ivey, Richard G; Voytovich, Uliana J; Moore, Heather D; Lin, Chenwei; Pogosova-Agadjanyan, Era L; Stirewalt, Derek L; Reding, Kerryn W; Whiteaker, Jeffrey R; Paulovich, Amanda G.

Mol Cell Proteomics; 15(2): 726-39, 2016 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-26621847

7.

Quantification of ATP7B Protein in Dried Blood Spots by Peptide Immuno-SRM as a Potential Screen for Wilson's Disease.

Jung, Sunhee; Whiteaker, Jeffrey R; Zhao, Lei; Yoo, Han-Wook; Paulovich, Amanda G; Hahn, Si Houn.

J Proteome Res; 16(2): 862-871, 2017 02 03.

Artigo em Inglês | MEDLINE | ID: mdl-27935710

8.

Demonstrating the feasibility of large-scale development of standardized assays to quantify human proteins.

Kennedy, Jacob J; Abbatiello, Susan E; Kim, Kyunggon; Yan, Ping; Whiteaker, Jeffrey R; Lin, Chenwei; Kim, Jun Seok; Zhang, Yuzheng; Wang, Xianlong; Ivey, Richard G; Zhao, Lei; Min, Hophil; Lee, Youngju; Yu, Myeong-Hee; Yang, Eun Gyeong; Lee, Cheolju; Wang, Pei; Rodriguez, Henry; Kim, Youngsoo; Carr, Steven A; Paulovich, Amanda G.

Nat Methods; 11(2): 149-55, 2014 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-24317253

9.

Peptide Immunoaffinity Enrichment and Targeted Mass Spectrometry Enables Multiplex, Quantitative Pharmacodynamic Studies of Phospho-Signaling.

Whiteaker, Jeffrey R; Zhao, Lei; Yan, Ping; Ivey, Richard G; Voytovich, Uliana J; Moore, Heather D; Lin, Chenwei; Paulovich, Amanda G.

Mol Cell Proteomics; 14(8): 2261-73, 2015 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-25987412

10.

Anti-peptide monoclonal antibodies generated for immuno-multiple reaction monitoring-mass spectrometry assays have a high probability of supporting Western blot and ELISA.

Schoenherr, Regine M; Saul, Richard G; Whiteaker, Jeffrey R; Yan, Ping; Whiteley, Gordon R; Paulovich, Amanda G.

Mol Cell Proteomics; 14(2): 382-98, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25512614

11.

Large-Scale Interlaboratory Study to Develop, Analytically Validate and Apply Highly Multiplexed, Quantitative Peptide Assays to Measure Cancer-Relevant Proteins in Plasma.

Abbatiello, Susan E; Schilling, Birgit; Mani, D R; Zimmerman, Lisa J; Hall, Steven C; MacLean, Brendan; Albertolle, Matthew; Allen, Simon; Burgess, Michael; Cusack, Michael P; Gosh, Mousumi; Hedrick, Victoria; Held, Jason M; Inerowicz, H Dorota; Jackson, Angela; Keshishian, Hasmik; Kinsinger, Christopher R; Lyssand, John; Makowski, Lee; Mesri, Mehdi; Rodriguez, Henry; Rudnick, Paul; Sadowski, Pawel; Sedransk, Nell; Shaddox, Kent; Skates, Stephen J; Kuhn, Eric; Smith, Derek; Whiteaker, Jeffery R; Whitwell, Corbin; Zhang, Shucha; Borchers, Christoph H; Fisher, Susan J; Gibson, Bradford W; Liebler, Daniel C; MacCoss, Michael J; Neubert, Thomas A; Paulovich, Amanda G; Regnier, Fred E; Tempst, Paul; Carr, Steven A.

Mol Cell Proteomics; 14(9): 2357-74, 2015 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-25693799

12.

Commercially available antibodies can be applied in quantitative multiplexed peptide immunoaffinity enrichment targeted mass spectrometry assays.

Schoenherr, Regine M; Zhao, Lei; Ivey, Richard G; Voytovich, Uliana J; Kennedy, Jacob; Yan, Ping; Lin, Chenwei; Whiteaker, Jeffrey R; Paulovich, Amanda G.

Proteomics; 16(15-16): 2141-5, 2016 08.

Artigo em Inglês | MEDLINE | ID: mdl-27094115

13.

Optimized Protocol for Quantitative Multiple Reaction Monitoring-Based Proteomic Analysis of Formalin-Fixed, Paraffin-Embedded Tissues.

Kennedy, Jacob J; Whiteaker, Jeffrey R; Schoenherr, Regine M; Yan, Ping; Allison, Kimberly; Shipley, Melissa; Lerch, Melissa; Hoofnagle, Andrew N; Baird, Geoffrey Stuart; Paulovich, Amanda G.

J Proteome Res; 15(8): 2717-28, 2016 08 05.

Artigo em Inglês | MEDLINE | ID: mdl-27462933

14.

Ischemia in tumors induces early and sustained phosphorylation changes in stress kinase pathways but does not affect global protein levels.

Mertins, Philipp; Yang, Feng; Liu, Tao; Mani, D R; Petyuk, Vladislav A; Gillette, Michael A; Clauser, Karl R; Qiao, Jana W; Gritsenko, Marina A; Moore, Ronald J; Levine, Douglas A; Townsend, Reid; Erdmann-Gilmore, Petra; Snider, Jacqueline E; Davies, Sherri R; Ruggles, Kelly V; Fenyo, David; Kitchens, R Thomas; Li, Shunqiang; Olvera, Narciso; Dao, Fanny; Rodriguez, Henry; Chan, Daniel W; Liebler, Daniel; White, Forest; Rodland, Karin D; Mills, Gordon B; Smith, Richard D; Paulovich, Amanda G; Ellis, Matthew; Carr, Steven A.

Mol Cell Proteomics; 13(7): 1690-704, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-24719451

15.

Targeted peptide measurements in biology and medicine: best practices for mass spectrometry-based assay development using a fit-for-purpose approach.

Carr, Steven A; Abbatiello, Susan E; Ackermann, Bradley L; Borchers, Christoph; Domon, Bruno; Deutsch, Eric W; Grant, Russell P; Hoofnagle, Andrew N; Hüttenhain, Ruth; Koomen, John M; Liebler, Daniel C; Liu, Tao; MacLean, Brendan; Mani, D R; Mansfield, Elizabeth; Neubert, Hendrik; Paulovich, Amanda G; Reiter, Lukas; Vitek, Olga; Aebersold, Ruedi; Anderson, Leigh; Bethem, Robert; Blonder, Josip; Boja, Emily; Botelho, Julianne; Boyne, Michael; Bradshaw, Ralph A; Burlingame, Alma L; Chan, Daniel; Keshishian, Hasmik; Kuhn, Eric; Kinsinger, Christopher; Lee, Jerry S H; Lee, Sang-Won; Moritz, Robert; Oses-Prieto, Juan; Rifai, Nader; Ritchie, James; Rodriguez, Henry; Srinivas, Pothur R; Townsend, R Reid; Van Eyk, Jennifer; Whiteley, Gordon; Wiita, Arun; Weintraub, Susan.

Mol Cell Proteomics; 13(3): 907-17, 2014 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-24443746

16.

Antibody-Coupled Magnetic Beads Can Be Reused in Immuno-MRM Assays To Reduce Cost and Extend Antibody Supply.

Zhao, Lei; Whiteaker, Jeffrey R; Voytovich, Uliana J; Ivey, Richard G; Paulovich, Amanda G.

J Proteome Res; 14(10): 4425-31, 2015 Oct 02.

Artigo em Inglês | MEDLINE | ID: mdl-26302155

17.

High-affinity recombinant antibody fragments (Fabs) can be applied in peptide enrichment immuno-MRM assays.

Whiteaker, Jeffrey R; Zhao, Lei; Frisch, Christian; Ylera, Francisco; Harth, Stefan; Knappik, Achim; Paulovich, Amanda G.

J Proteome Res; 13(4): 2187-96, 2014 Apr 04.

Artigo em Inglês | MEDLINE | ID: mdl-24568200

18.

Panorama: a targeted proteomics knowledge base.

Sharma, Vagisha; Eckels, Josh; Taylor, Greg K; Shulman, Nicholas J; Stergachis, Andrew B; Joyner, Shannon A; Yan, Ping; Whiteaker, Jeffrey R; Halusa, Goran N; Schilling, Birgit; Gibson, Bradford W; Colangelo, Christopher M; Paulovich, Amanda G; Carr, Steven A; Jaffe, Jacob D; MacCoss, Michael J; MacLean, Brendan.

J Proteome Res; 13(9): 4205-10, 2014 Sep 05.

Artigo em Inglês | MEDLINE | ID: mdl-25102069

19.

Sequential multiplexed analyte quantification using peptide immunoaffinity enrichment coupled to mass spectrometry.

Whiteaker, Jeffrey R; Zhao, Lei; Lin, Chenwei; Yan, Ping; Wang, Pei; Paulovich, Amanda G.

Mol Cell Proteomics; 11(6): M111.015347, 2012 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-22203691

20.

Interlaboratory evaluation of automated, multiplexed peptide immunoaffinity enrichment coupled to multiple reaction monitoring mass spectrometry for quantifying proteins in plasma.

Kuhn, Eric; Whiteaker, Jeffrey R; Mani, D R; Jackson, Angela M; Zhao, Lei; Pope, Matthew E; Smith, Derek; Rivera, Keith D; Anderson, N Leigh; Skates, Steven J; Pearson, Terry W; Paulovich, Amanda G; Carr, Steven A.

Mol Cell Proteomics; 11(6): M111.013854, 2012 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-22199228

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