Pesquisa | Biblioteca Virtual em Saúde

1.

Ponatinib efficacy and safety in Philadelphia chromosome-positive leukemia: final 5-year results of the phase 2 PACE trial.

Cortes, Jorge E; Kim, Dong-Wook; Pinilla-Ibarz, Javier; le Coutre, Philipp D; Paquette, Ronald; Chuah, Charles; Nicolini, Franck E; Apperley, Jane F; Khoury, H Jean; Talpaz, Moshe; DeAngelo, Daniel J; Abruzzese, Elisabetta; Rea, Delphine; Baccarani, Michele; Müller, Martin C; Gambacorti-Passerini, Carlo; Lustgarten, Stephanie; Rivera, Victor M; Haluska, Frank G; Guilhot, François; Deininger, Michael W; Hochhaus, Andreas; Hughes, Timothy P; Shah, Neil P; Kantarjian, Hagop M.

Blood; 132(4): 393-404, 2018 Jul 26.

Artigo em Inglês | MEDLINE | ID: mdl-29567798

2.

Primary analysis of a phase II open-label trial of INCB039110, a selective JAK1 inhibitor, in patients with myelofibrosis.

Mascarenhas, John O; Talpaz, Moshe; Gupta, Vikas; Foltz, Lynda M; Savona, Michael R; Paquette, Ronald; Turner, A Robert; Coughlin, Paul; Winton, Elliott; Burn, Timothy C; O'Neill, Peter; Clark, Jason; Hunter, Deborah; Assad, Albert; Hoffman, Ronald; Verstovsek, Srdan.

Haematologica; 102(2): 327-335, 2017 02.

Artigo em Inglês | MEDLINE | ID: mdl-27789678

3.

A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis.

Verstovsek, Srdan; Mesa, Ruben A; Gotlib, Jason; Levy, Richard S; Gupta, Vikas; DiPersio, John F; Catalano, John V; Deininger, Michael; Miller, Carole; Silver, Richard T; Talpaz, Moshe; Winton, Elliott F; Harvey, Jimmie H; Arcasoy, Murat O; Hexner, Elizabeth; Lyons, Roger M; Paquette, Ronald; Raza, Azra; Vaddi, Kris; Erickson-Viitanen, Susan; Koumenis, Iphigenia L; Sun, William; Sandor, Victor; Kantarjian, Hagop M.

N Engl J Med; 366(9): 799-807, 2012 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-22375971

4.

Phase 2 study of the lenalidomide and azacitidine combination in patients with higher-risk myelodysplastic syndromes.

Sekeres, Mikkael A; Tiu, Ramon V; Komrokji, Rami; Lancet, Jeffrey; Advani, Anjali S; Afable, Manuel; Englehaupt, Ricki; Juersivich, Joyce; Cuthbertson, David; Paleveda, Jennifer; Tabarroki, Ali; Visconte, Valeria; Makishima, Hideki; Jerez, Andres; Paquette, Ronald; List, Alan F; Maciejewski, Jaroslaw P.

Blood; 120(25): 4945-51, 2012 Dec 13.

Artigo em Inglês | MEDLINE | ID: mdl-22915641

5.

A phase II multicenter rabbit anti-thymocyte globulin trial in patients with myelodysplastic syndromes identifying a novel model for response prediction.

Komrokji, Rami S; Mailloux, Adam W; Chen, Dung-Tsa; Sekeres, Mikkael A; Paquette, Ronald; Fulp, William J; Sugimori, Chiharu; Paleveda-Pena, Jennifer; Maciejewski, Jaroslaw P; List, Alan F; Epling-Burnette, Pearlie K.

Haematologica; 99(7): 1176-83, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-24488560

6.

Comparison of placebo and best available therapy for the treatment of myelofibrosis in the phase 3 COMFORT studies.

Mesa, Ruben A; Kiladjian, Jean-Jacques; Verstovsek, Srdan; Al-Ali, Haifa Kathrin; Gotlib, Jason; Gisslinger, Heinz; Levy, Richard; Siulnik, Andres; Gupta, Vikas; Khan, Mahmudul; DiPersio, John F; McQuitty, Mari; Catalano, John V; Hunter, Deborah S; Knoops, Laurent; Deininger, Michael; Cervantes, Francisco; Miller, Carole; Vannucchi, Alessandro M; Silver, Richard T; Barbui, Tiziano; Talpaz, Moshe; Barosi, Giovanni; Winton, Elliott F; Mendeson, Estella; Harvey, Jimmie H; Arcasoy, Murat O; Hexner, Elizabeth; Lyons, Roger M; Paquette, Ronald; Raza, Azra; Sun, William; Sandor, Victor; Kantarjian, Hagop M; Harrison, Claire.

Haematologica; 99(2): 292-8, 2014 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-23911705

7.

Expansion of effector memory regulatory T cells represents a novel prognostic factor in lower risk myelodysplastic syndrome.

Mailloux, Adam W; Sugimori, Chiharu; Komrokji, Rami S; Yang, Lili; Maciejewski, Jaroslaw P; Sekeres, Mikkael A; Paquette, Ronald; Loughran, Thomas P; List, Alan F; Epling-Burnette, Pearlie K.

J Immunol; 189(6): 3198-208, 2012 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-22875800

8.

The clinical benefit of ruxolitinib across patient subgroups: analysis of a placebo-controlled, Phase III study in patients with myelofibrosis.

Verstovsek, Srdan; Mesa, Ruben A; Gotlib, Jason; Levy, Richard S; Gupta, Vikas; DiPersio, John F; Catalano, John V; Deininger, Michael; Miller, Carole; Silver, Richard T; Talpaz, Moshe; Winton, Elliott F; Harvey, Jimmie H; Arcasoy, Murat O; Hexner, Elizabeth; Lyons, Roger M; Paquette, Ronald; Raza, Azra; Vaddi, Kris; Erickson-Viitanen, Susan; Sun, William; Sandor, Victor; Kantarjian, Hagop M.

Br J Haematol; 161(4): 508-16, 2013 May.

Artigo em Inglês | MEDLINE | ID: mdl-23480528

9.

Clonal drift demonstrates unexpected dynamics of the T-cell repertoire in T-large granular lymphocyte leukemia.

Clemente, Michael J; Wlodarski, Marcin W; Makishima, Hideki; Viny, Aaron D; Bretschneider, Isabell; Shaik, Mohammad; Bejanyan, Nelli; Lichtin, Alan E; Hsi, Eric D; His, Eric D; Paquette, Ronald L; Loughran, Thomas P; Maciejewski, Jaroslaw P.

Blood; 118(16): 4384-93, 2011 Oct 20.

Artigo em Inglês | MEDLINE | ID: mdl-21865345

10.

Prognostic impact of SNP array karyotyping in myelodysplastic syndromes and related myeloid malignancies.

Tiu, Ramon V; Gondek, Lukasz P; O'Keefe, Christine L; Elson, Paul; Huh, Jungwon; Mohamedali, Azim; Kulasekararaj, Austin; Advani, Anjali S; Paquette, Ronald; List, Alan F; Sekeres, Mikkael A; McDevitt, Michael A; Mufti, Ghulam J; Maciejewski, Jaroslaw P.

Blood; 117(17): 4552-60, 2011 Apr 28.

Artigo em Inglês | MEDLINE | ID: mdl-21285439

11.

CBL, CBLB, TET2, ASXL1, and IDH1/2 mutations and additional chromosomal aberrations constitute molecular events in chronic myelogenous leukemia.

Makishima, Hideki; Jankowska, Anna M; McDevitt, Michael A; O'Keefe, Christine; Dujardin, Simon; Cazzolli, Heather; Przychodzen, Bartlomiej; Prince, Courtney; Nicoll, John; Siddaiah, Harish; Shaik, Mohammed; Szpurka, Hadrian; Hsi, Eric; Advani, Anjali; Paquette, Ronald; Maciejewski, Jaroslaw P.

Blood; 117(21): e198-206, 2011 May 26.

Artigo em Inglês | MEDLINE | ID: mdl-21346257

12.

Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I.

Verstovsek, Srdan; Mesa, Ruben A; Gotlib, Jason; Levy, Richard S; Gupta, Vikas; DiPersio, John F; Catalano, John V; Deininger, Michael W N; Miller, Carole B; Silver, Richard T; Talpaz, Moshe; Winton, Elliott F; Harvey, Jimmie H; Arcasoy, Murat O; Hexner, Elizabeth O; Lyons, Roger M; Paquette, Ronald; Raza, Azra; Vaddi, Kris; Erickson-Viitanen, Susan; Sun, William; Sandor, Victor; Kantarjian, Hagop M.

Haematologica; 98(12): 1865-71, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-24038026

13.

SNP array analysis of tyrosine kinase inhibitor-resistant chronic myeloid leukemia identifies heterogeneous secondary genomic alterations.

Nowak, Daniel; Ogawa, Seishi; Müschen, Markus; Kato, Motohiro; Kawamata, Norihiko; Meixel, Antonie; Nowak, Verena; Kim, Han S; Kang, Sharon; Paquette, Ronald; Chang, Mi-Sook; Thoennissen, Nils H; Thoenissen, Nils H; Mossner, Max; Hofmann, Wolf-Karsten; Kohlmann, Alexander; Weiss, Tamara; Haferlach, Torsten; Haferlach, Claudia; Koeffler, H Phillip.

Blood; 115(5): 1049-53, 2010 Feb 04.

Artigo em Inglês | MEDLINE | ID: mdl-19965645

14.

Sequential ABL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutations with altered oncogenic potency.

Shah, Neil P; Skaggs, Brian J; Branford, Susan; Hughes, Timothy P; Nicoll, John M; Paquette, Ronald L; Sawyers, Charles L.

J Clin Invest; 117(9): 2562-9, 2007 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-17710227

15.

Multiple BCR-ABL kinase domain mutations confer polyclonal resistance to the tyrosine kinase inhibitor imatinib (STI571) in chronic phase and blast crisis chronic myeloid leukemia.

Shah, Neil P; Nicoll, John M; Nagar, Bhushan; Gorre, Mercedes E; Paquette, Ronald L; Kuriyan, John; Sawyers, Charles L.

Cancer Cell; 2(2): 117-25, 2002 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-12204532

16.

Phase 2, single-arm trial to evaluate the effectiveness of darbepoetin alfa for correcting anaemia in patients with myelodysplastic syndromes.

Gabrilove, Janice; Paquette, Ronald; Lyons, Roger M; Mushtaq, Chaudhry; Sekeres, Mikkael A; Tomita, Dianne; Dreiling, Lyndah.

Br J Haematol; 142(3): 379-93, 2008 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-18540943

17.

Systemic mastocytosis with plasma cell dyscrasia: report of a case.

Pullarkat, Sheeja T; Sedarat, Franklin; Paquette, Ronald; Said, Jonathan.

Leuk Res; 32(7): 1160-3, 2008 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-18061667

18.

Acquired amegakaryocytic thrombocytopenia and pure red cell aplasia associated with an occult large granular lymphocyte leukemia.

Lai, Dominic W; Loughran, Thomas P; Maciejewski, Jaroslaw P; Sasu, Sebastian; Song, Sophie X; Epling-Burnette, P K; Paquette, Ronald L.

Leuk Res; 32(5): 823-7, 2008 May.

Artigo em Inglês | MEDLINE | ID: mdl-17915315

19.

Long-term survival in patients treated with ruxolitinib for myelofibrosis: COMFORT-I and -II pooled analyses.

Verstovsek, Srdan; Gotlib, Jason; Mesa, Ruben A; Vannucchi, Alessandro M; Kiladjian, Jean-Jacques; Cervantes, Francisco; Harrison, Claire N; Paquette, Ronald; Sun, William; Naim, Ahmad; Langmuir, Peter; Dong, Tuochuan; Gopalakrishna, Prashanth; Gupta, Vikas.

J Hematol Oncol; 10(1): 156, 2017 09 29.

Artigo em Inglês | MEDLINE | ID: mdl-28962635

20.

Correction: Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia.

Sun, Haibo; Lin, De-Chen; Guo, Xiao; Masouleh, Behzad Kharabi; Gery, Sigal; Cao, Qi; Alkan, Serhan; Ikezoe, Takayuki; Akiba, Chie; Paquette, Ronald; Chien, Wenwen; Müller-Tidow, Carsten; Jing, Yang; Agelopoulos, Konstantin; Müschen, Markus; Koeffler, H Phillip.

Oncotarget; 8(38): 64651, 2017 Sep 08.

Artigo em Inglês | MEDLINE | ID: mdl-28969101

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