Pesquisa | Biblioteca Virtual em Saúde

1.

Nuclear Genomic Instability and Aging.

Niedernhofer, Laura J; Gurkar, Aditi U; Wang, Yinsheng; Vijg, Jan; Hoeijmakers, Jan H J; Robbins, Paul D.

Annu Rev Biochem; 87: 295-322, 2018 Jun 20.

Artigo em Inglês | MEDLINE | ID: mdl-29925262

2.

Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation.

Zhao, Jing; Zhang, Lei; Mu, Xiaodong; Doebelin, Christelle; Nguyen, William; Wallace, Callen; Reay, Daniel P; McGowan, Sara J; Corbo, Lana; Clemens, Paula R; Wilson, Gabriela Mustata; Watkins, Simon C; Solt, Laura A; Cameron, Michael D; Huard, Johnny; Niedernhofer, Laura J; Kamenecka, Theodore M; Robbins, Paul D.

PLoS Biol; 16(6): e2004663, 2018 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-29889904

3.

Adenoviral gene transfer of a single-chain IL-23 induces psoriatic arthritis-like symptoms in NOD mice.

Flores, Rafael R; Carbo, Lana; Kim, Eun; Van Meter, Montina; De Padilla, Consuelo M Lopez; Zhao, Jing; Colangelo, Debora; Yousefzadeh, Matthew J; Angelini, Luise A; Zhang, Lei; Pola, Enrico; Vo, Nam; Evans, Christopher H; Gambotto, Andrea; Niedernhofer, Laura J; Robbins, Paul D.

FASEB J; 33(8): 9505-9515, 2019 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-31170010

4.

Signal Transduction, Ageing and Disease.

Zhang, Lei; Yousefzadeh, Matthew J; Suh, Yousin; Niedernhofer, Laura J; Robbins, Paul D.

Subcell Biochem; 91: 227-247, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-30888655

5.

ERCC4 variants identified in a cohort of patients with segmental progeroid syndromes.

Mori, Takayasu; Yousefzadeh, Matthew J; Faridounnia, Maryam; Chong, Jessica X; Hisama, Fuki M; Hudgins, Louanne; Mercado, Gabriela; Wade, Erin A; Barghouthy, Amira S; Lee, Lin; Martin, George M; Nickerson, Deborah A; Bamshad, Michael J; Niedernhofer, Laura J; Oshima, Junko.

Hum Mutat; 39(2): 255-265, 2018 02.

Artigo em Inglês | MEDLINE | ID: mdl-29105242

6.

In vivo detection and replication studies of α-anomeric lesions of 2'-deoxyribonucleosides.

Amato, Nicholas J; Zhai, Qianqian; Navarro, Diana C; Niedernhofer, Laura J; Wang, Yinsheng.

Nucleic Acids Res; 43(17): 8314-24, 2015 Sep 30.

Artigo em Inglês | MEDLINE | ID: mdl-26202973

7.

Smartphone Analytics: Mobilizing the Lab into the Cloud for Omic-Scale Analyses.

Montenegro-Burke, J Rafael; Phommavongsay, Thiery; Aisporna, Aries E; Huan, Tao; Rinehart, Duane; Forsberg, Erica; Poole, Farris L; Thorgersen, Michael P; Adams, Michael W W; Krantz, Gregory; Fields, Matthew W; Northen, Trent R; Robbins, Paul D; Niedernhofer, Laura J; Lairson, Luke; Benton, H Paul; Siuzdak, Gary.

Anal Chem; 88(19): 9753-9758, 2016 10 04.

Artigo em Inglês | MEDLINE | ID: mdl-27560777

8.

Occurrence, Biological Consequences, and Human Health Relevance of Oxidative Stress-Induced DNA Damage.

Yu, Yang; Cui, Yuxiang; Niedernhofer, Laura J; Wang, Yinsheng.

Chem Res Toxicol; 29(12): 2008-2039, 2016 12 19.

Artigo em Inglês | MEDLINE | ID: mdl-27989142

9.

Simultaneous Quantification of Methylated Cytidine and Adenosine in Cellular and Tissue RNA by Nano-Flow Liquid Chromatography-Tandem Mass Spectrometry Coupled with the Stable Isotope-Dilution Method.

Fu, Lijuan; Amato, Nicholas J; Wang, Pengcheng; McGowan, Sara J; Niedernhofer, Laura J; Wang, Yinsheng.

Anal Chem; 87(15): 7653-9, 2015 Aug 04.

Artigo em Inglês | MEDLINE | ID: mdl-26158405

10.

Systems biology guided by XCMS Online metabolomics.

Huan, Tao; Forsberg, Erica M; Rinehart, Duane; Johnson, Caroline H; Ivanisevic, Julijana; Benton, H Paul; Fang, Mingliang; Aisporna, Aries; Hilmers, Brian; Poole, Farris L; Thorgersen, Michael P; Adams, Michael W W; Krantz, Gregory; Fields, Matthew W; Robbins, Paul D; Niedernhofer, Laura J; Ideker, Trey; Majumder, Erica L; Wall, Judy D; Rattray, Nicholas J W; Goodacre, Royston; Lairson, Luke L; Siuzdak, Gary.

Nat Methods; 14(5): 461-462, 2017 Apr 27.

Artigo em Inglês | MEDLINE | ID: mdl-28448069

11.

Tet-mediated formation of 5-hydroxymethylcytosine in RNA.

Fu, Lijuan; Guerrero, Candace R; Zhong, Na; Amato, Nicholas J; Liu, Yunhua; Liu, Shuo; Cai, Qian; Ji, Debin; Jin, Seung-Gi; Niedernhofer, Laura J; Pfeifer, Gerd P; Xu, Guo-Liang; Wang, Yinsheng.

J Am Chem Soc; 136(33): 11582-5, 2014 Aug 20.

Artigo em Inglês | MEDLINE | ID: mdl-25073028

12.

Choline phosphate cytidylyltransferase-α is a novel antigen detected by the anti-ERCC1 antibody 8F1 with biomarker value in patients with lung and head and neck squamous cell carcinomas.

Vaezi, Alec E; Bepler, Gerold; Bhagwat, Nikhil R; Malysa, Agnes; Rubatt, Jennifer M; Chen, Wei; Hood, Brian L; Conrads, Thomas P; Wang, Lin; Kemp, Carolyn E; Niedernhofer, Laura J.

Cancer; 120(12): 1898-907, 2014 Jun 15.

Artigo em Inglês | MEDLINE | ID: mdl-24692084

13.

Cell autonomous and nonautonomous mechanisms drive hematopoietic stem/progenitor cell loss in the absence of DNA repair.

Cho, Joon Seok; Kook, Sung Ho; Robinson, Andria Rasile; Niedernhofer, Laura J; Lee, Byeong-Chel.

Stem Cells; 31(3): 511-25, 2013 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-23097336

14.

A quantitative assay for assessing the effects of DNA lesions on transcription.

You, Changjun; Dai, Xiaoxia; Yuan, Bifeng; Wang, Jin; Wang, Jianshuang; Brooks, Philip J; Niedernhofer, Laura J; Wang, Yinsheng.

Nat Chem Biol; 8(10): 817-22, 2012 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-22902614

15.

Endogenous formation and repair of oxidatively induced G[8-5 m]T intrastrand cross-link lesion.

Wang, Jin; Cao, Huachuan; You, Changjun; Yuan, Bifeng; Bahde, Ralf; Gupta, Sanjeev; Nishigori, Chikako; Niedernhofer, Laura J; Brooks, Philip J; Wang, Yinsheng.

Nucleic Acids Res; 40(15): 7368-74, 2012 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-22581771

16.

Multiple DNA binding domains mediate the function of the ERCC1-XPF protein in nucleotide excision repair.

Su, Yan; Orelli, Barbara; Madireddy, Advaitha; Niedernhofer, Laura J; Schärer, Orlando D.

J Biol Chem; 287(26): 21846-55, 2012 Jun 22.

Artigo em Inglês | MEDLINE | ID: mdl-22547097

17.

A mouse model of accelerated liver aging caused by a defect in DNA repair.

Gregg, Siobhán Q; Gutiérrez, Verónica; Robinson, Andria Rasile; Woodell, Tyler; Nakao, Atsunori; Ross, Mark A; Michalopoulos, George K; Rigatti, Lora; Rothermel, Carrie E; Kamileri, Irene; Garinis, George A; Stolz, Donna Beer; Niedernhofer, Laura J.

Hepatology; 55(2): 609-21, 2012 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-21953681

18.

NF-κB negatively impacts the myogenic potential of muscle-derived stem cells.

Lu, Aiping; Proto, Jonathan D; Guo, Lulin; Tang, Ying; Lavasani, Mitra; Tilstra, Jeremy S; Niedernhofer, Laura J; Wang, Bing; Guttridge, Denis C; Robbins, Paul D; Huard, Johnny.

Mol Ther; 20(3): 661-8, 2012 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-22158056

19.

Hyper telomere recombination accelerates replicative senescence and may promote premature aging.

Hagelstrom, R Tanner; Blagoev, Krastan B; Niedernhofer, Laura J; Goodwin, Edwin H; Bailey, Susan M.

Proc Natl Acad Sci U S A; 107(36): 15768-73, 2010 Sep 07.

Artigo em Inglês | MEDLINE | ID: mdl-20798040

20.

Mislocalization of XPF-ERCC1 nuclease contributes to reduced DNA repair in XP-F patients.

Ahmad, Anwaar; Enzlin, Jacqueline H; Bhagwat, Nikhil R; Wijgers, Nils; Raams, Anja; Appledoorn, Esther; Theil, Arjan F; J Hoeijmakers, Jan H; Vermeulen, Wim; J Jaspers, Nicolaas G; Schärer, Orlando D; Niedernhofer, Laura J.

PLoS Genet; 6(3): e1000871, 2010 Mar 05.

Artigo em Inglês | MEDLINE | ID: mdl-20221251

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