Pesquisa | Biblioteca Virtual em Saúde

1.

Higher-Order Inter-chromosomal Hubs Shape 3D Genome Organization in the Nucleus.

Quinodoz, Sofia A; Ollikainen, Noah; Tabak, Barbara; Palla, Ali; Schmidt, Jan Marten; Detmar, Elizabeth; Lai, Mason M; Shishkin, Alexander A; Bhat, Prashant; Takei, Yodai; Trinh, Vickie; Aznauryan, Erik; Russell, Pamela; Cheng, Christine; Jovanovic, Marko; Chow, Amy; Cai, Long; McDonel, Patrick; Garber, Manuel; Guttman, Mitchell.

Cell; 174(3): 744-757.e24, 2018 Jul 26.

Artigo em Inglês | MEDLINE | ID: mdl-29887377

2.

Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits.

Ulirsch, Jacob C; Nandakumar, Satish K; Wang, Li; Giani, Felix C; Zhang, Xiaolan; Rogov, Peter; Melnikov, Alexandre; McDonel, Patrick; Do, Ron; Mikkelsen, Tarjei S; Sankaran, Vijay G.

Cell; 165(6): 1530-1545, 2016 Jun 02.

Artigo em Inglês | MEDLINE | ID: mdl-27259154

3.

Ebola Virus Glycoprotein with Increased Infectivity Dominated the 2013-2016 Epidemic.

Diehl, William E; Lin, Aaron E; Grubaugh, Nathan D; Carvalho, Luiz Max; Kim, Kyusik; Kyawe, Pyae Phyo; McCauley, Sean M; Donnard, Elisa; Kucukural, Alper; McDonel, Patrick; Schaffner, Stephen F; Garber, Manuel; Rambaut, Andrew; Andersen, Kristian G; Sabeti, Pardis C; Luban, Jeremy.

Cell; 167(4): 1088-1098.e6, 2016 11 03.

Artigo em Inglês | MEDLINE | ID: mdl-27814506

4.

RNA-RNA interactions enable specific targeting of noncoding RNAs to nascent Pre-mRNAs and chromatin sites.

Engreitz, Jesse M; Sirokman, Klara; McDonel, Patrick; Shishkin, Alexander A; Surka, Christine; Russell, Pamela; Grossman, Sharon R; Chow, Amy Y; Guttman, Mitchell; Lander, Eric S.

Cell; 159(1): 188-199, 2014 Sep 25.

Artigo em Inglês | MEDLINE | ID: mdl-25259926

5.

Local regulation of gene expression by lncRNA promoters, transcription and splicing.

Engreitz, Jesse M; Haines, Jenna E; Perez, Elizabeth M; Munson, Glen; Chen, Jenny; Kane, Michael; McDonel, Patrick E; Guttman, Mitchell; Lander, Eric S.

Nature; 539(7629): 452-455, 2016 11 17.

Artigo em Inglês | MEDLINE | ID: mdl-27783602

6.

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3.

McHugh, Colleen A; Chen, Chun-Kan; Chow, Amy; Surka, Christine F; Tran, Christina; McDonel, Patrick; Pandya-Jones, Amy; Blanco, Mario; Burghard, Christina; Moradian, Annie; Sweredoski, Michael J; Shishkin, Alexander A; Su, Julia; Lander, Eric S; Hess, Sonja; Plath, Kathrin; Guttman, Mitchell.

Nature; 521(7551): 232-6, 2015 May 14.

Artigo em Inglês | MEDLINE | ID: mdl-25915022

7.

Keeping things quiet: roles of NuRD and Sin3 co-repressor complexes during mammalian development.

McDonel, Patrick; Costello, Ita; Hendrich, Brian.

Int J Biochem Cell Biol; 41(1): 108-16, 2009 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-18775506

8.

Insight into GATA1 transcriptional activity through interrogation of cis elements disrupted in human erythroid disorders.

Wakabayashi, Aoi; Ulirsch, Jacob C; Ludwig, Leif S; Fiorini, Claudia; Yasuda, Makiko; Choudhuri, Avik; McDonel, Patrick; Zon, Leonard I; Sankaran, Vijay G.

Proc Natl Acad Sci U S A; 113(16): 4434-9, 2016 Apr 19.

Artigo em Inglês | MEDLINE | ID: mdl-27044088

9.

Multiple cell and population-level interactions with mouse embryonic stem cell heterogeneity.

Cannon, Danielle; Corrigan, Adam M; Miermont, Agnes; McDonel, Patrick; Chubb, Jonathan R.

Development; 142(16): 2840-9, 2015 Aug 15.

Artigo em Inglês | MEDLINE | ID: mdl-26209649

10.

Sin3a is essential for the genome integrity and viability of pluripotent cells.

McDonel, Patrick; Demmers, Jeroen; Tan, David W M; Watt, Fiona; Hendrich, Brian D.

Dev Biol; 363(1): 62-73, 2012 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-22206758

11.

Clustered DNA motifs mark X chromosomes for repression by a dosage compensation complex.

McDonel, Patrick; Jans, Judith; Peterson, Brant K; Meyer, Barbara J.

Nature; 444(7119): 614-8, 2006 Nov 30.

Artigo em Inglês | MEDLINE | ID: mdl-17122774

12.

Approaches for Understanding the Mechanisms of Long Noncoding RNA Regulation of Gene Expression.

McDonel, Patrick; Guttman, Mitchell.

Cold Spring Harb Perspect Biol; 11(12)2019 Dec 02.

Artigo em Inglês | MEDLINE | ID: mdl-31791999

13.

Comparative Analysis of Immune Cells Reveals a Conserved Regulatory Lexicon.

Donnard, Elisa; Vangala, Pranitha; Afik, Shaked; McCauley, Sean; Nowosielska, Anetta; Kucukural, Alper; Tabak, Barbara; Zhu, Xiaopeng; Diehl, William; McDonel, Patrick; Yosef, Nir; Luban, Jeremy; Garber, Manuel.

Cell Syst; 6(3): 381-394.e7, 2018 Mar 28.

Artigo em Inglês | MEDLINE | ID: mdl-29454939

14.

Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing.

Chen, Chun-Kan; Blanco, Mario; Jackson, Constanza; Aznauryan, Erik; Ollikainen, Noah; Surka, Christine; Chow, Amy; Cerase, Andrea; McDonel, Patrick; Guttman, Mitchell.

Science; 354(6311): 468-472, 2016 10 28.

Artigo em Inglês | MEDLINE | ID: mdl-27492478

15.

The Xist lncRNA exploits three-dimensional genome architecture to spread across the X chromosome.

Engreitz, Jesse M; Pandya-Jones, Amy; McDonel, Patrick; Shishkin, Alexander; Sirokman, Klara; Surka, Christine; Kadri, Sabah; Xing, Jeffrey; Goren, Alon; Lander, Eric S; Plath, Kathrin; Guttman, Mitchell.

Science; 341(6147): 1237973, 2013 Aug 16.

Artigo em Inglês | MEDLINE | ID: mdl-23828888

16.

Recruitment and spreading of the C. elegans dosage compensation complex along X chromosomes.

Csankovszki, Györgyi; McDonel, Patrick; Meyer, Barbara J.

Science; 303(5661): 1182-5, 2004 Feb 20.

Artigo em Inglês | MEDLINE | ID: mdl-14976312

17.

Phylogenetic relationships in Gleditsia (Leguminosae) based on ITS sequences.

Schnabel, Andrew; McDonel, Patrick E; Wendel, Jonathan F.

Am J Bot; 90(2): 310-20, 2003 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-21659122

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