Pesquisa | Biblioteca Virtual em Saúde

1.

Effect of IL-17 receptor A blockade with brodalumab in inflammatory diseases.

Nirula, Ajay; Nilsen, Jon; Klekotka, Paul; Kricorian, Greg; Erondu, Ngozi; Towne, Jennifer E; Russell, Chris B; Martin, David A; Budelsky, Alison L.

Rheumatology (Oxford); 55(suppl 2): ii43-ii55, 2016 12.

Artigo em Inglês | MEDLINE | ID: mdl-27856660

2.

The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses.

Lowes, Michelle A; Russell, Chris B; Martin, David A; Towne, Jennifer E; Krueger, James G.

Trends Immunol; 34(4): 174-81, 2013 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-23291100

3.

Gene expression profiles normalized in psoriatic skin by treatment with brodalumab, a human anti-IL-17 receptor monoclonal antibody.

Russell, Chris B; Rand, Hugh; Bigler, Jeannette; Kerkof, Keith; Timour, Martin; Bautista, Edgar; Krueger, James G; Salinger, David H; Welcher, Andrew A; Martin, David A.

J Immunol; 192(8): 3828-36, 2014 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-24646743

4.

Pharmacokinetic and pharmacodynamic relationship of AMG 811, an anti-IFN-Î³ IgG1 monoclonal antibody, in patients with systemic lupus erythematosus.

Chen, Ping; Vu, Thuy; Narayanan, Adimoolam; Sohn, Winnie; Wang, Jin; Boedigheimer, Michael; Welcher, Andrew A; Sullivan, Barbara; Martin, David A; Ruixo, Juan Jose Perez; Ma, Peiming.

Pharm Res; 32(2): 640-53, 2015 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-25213774

5.

Improved virologic outcomes over time for HIV-infected patients on antiretroviral therapy in a cohort from Rio de Janeiro, 1997-2011.

Martin, David A; Luz, Paula M; Lake, Jordan E; Clark, Jesse L; Veloso, Valdilea G; Moreira, Ronaldo I; Cardoso, Sandra W; Klausner, Jeffrey D; Grinsztejn, Beatriz.

BMC Infect Dis; 14: 322, 2014 Jun 11.

Artigo em Inglês | MEDLINE | ID: mdl-24919778

6.

Autoantibodies make a U-turn: the toll hypothesis for autoantibody specificity.

Martin, David A; Elkon, Keith B.

J Exp Med; 202(11): 1465-9, 2005 Dec 05.

Artigo em Inglês | MEDLINE | ID: mdl-16330812

7.

The Effects of Hallucinogens on Gene Expression.

Martin, David A; Nichols, Charles D.

Curr Top Behav Neurosci; 36: 137-158, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-28677095

8.

Brief Report: Pharmacodynamics, Safety, and Clinical Efficacy of AMG 811, a Human Anti-Interferon-Î³ Antibody, in Patients With Discoid Lupus Erythematosus.

Werth, Victoria P; Fiorentino, David; Sullivan, Barbara A; Boedigheimer, Michael J; Chiu, Kit; Wang, Christine; Arnold, Gregory E; Damore, Michael A; Bigler, Jeannette; Welcher, Andrew A; Russell, Chris B; Martin, David A; Chung, James B.

Arthritis Rheumatol; 69(5): 1028-1034, 2017 05.

Artigo em Inglês | MEDLINE | ID: mdl-28118537

9.

Safety, pharmacokinetics and pharmacodynamics of AMG 811, an anti-interferon-Î³ monoclonal antibody, in SLE subjects without or with lupus nephritis.

Boedigheimer, Michael J; Martin, David A; Amoura, Zahir; Sánchez-Guerrero, Jorge; Romero-Diaz, Juanita; Kivitz, Alan; Aranow, Cynthia; Chan, Tak Mao; Chong, Yip Boon; Chiu, Kit; Wang, Christine; Sohn, Winnie; Arnold, Gregory E; Damore, Michael A; Welcher, Andrew A; Sullivan, Barbara A; Kotzin, Brian L; Chung, James B.

Lupus Sci Med; 4(1): e000226, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-29018537

10.

Psychedelics Recruit Multiple Cellular Types and Produce Complex Transcriptional Responses Within the Brain.

Martin, David A; Nichols, Charles D.

EBioMedicine; 11: 262-277, 2016 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-27649637

11.

Mechanisms of apoptosis.

Martin, David A; Elkon, Keith B.

Rheum Dis Clin North Am; 30(3): 441-54, vii, 2004 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-15261335

12.

Probing the motivational circuitry of binge eating.

Martin, David A; Calu, Donna J.

Neuropsychopharmacology; 2019 Nov 18.

Artigo em Inglês | MEDLINE | ID: mdl-31740747

13.

Chronic LSD alters gene expression profiles in the mPFC relevant to schizophrenia.

Martin, David A; Marona-Lewicka, Danuta; Nichols, David E; Nichols, Charles D.

Neuropharmacology; 83: 1-8, 2014 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-24704148

14.

A semi-mechanistic model to characterize the pharmacokinetics and pharmacodynamics of brodalumab in healthy volunteers and subjects with psoriasis in a first-in-human single ascending dose study.

Salinger, David H; Endres, Christopher J; Martin, David A; Gibbs, Megan A.

Clin Pharmacol Drug Dev; 3(4): 276-83, 2014 07.

Artigo em Inglês | MEDLINE | ID: mdl-27128833

15.

Population pharmacokinetics of brodalumab in healthy adults and adults with psoriasis from single and multiple dose studies.

Endres, Christopher J; Salinger, David H; Köck, Kathleen; Gastonguay, Marc R; Martin, David A; Klekotka, Paul; Nirula, Ajay; Gibbs, Megan A.

J Clin Pharmacol; 54(11): 1230-8, 2014 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-24846347

16.

The emerging role of IL-17 in the pathogenesis of psoriasis: preclinical and clinical findings.

Martin, David A; Towne, Jennifer E; Kricorian, Gregory; Klekotka, Paul; Gudjonsson, Johann E; Krueger, James G; Russell, Chris B.

J Invest Dermatol; 133(1): 17-26, 2013 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-22673731

17.

A phase Ib multiple ascending dose study evaluating safety, pharmacokinetics, and early clinical response of brodalumab, a human anti-IL-17R antibody, in methotrexate-resistant rheumatoid arthritis.

Martin, David A; Churchill, Melvin; Flores-Suarez, Luis; Cardiel, Mario H; Wallace, Daniel; Martin, Richard; Phillips, Kristine; Kaine, Jeffrey L; Dong, Hua; Salinger, David; Stevens, Erin; Russell, Chris B; Chung, James B.

Arthritis Res Ther; 15(5): R164, 2013 Oct 25.

Artigo em Inglês | MEDLINE | ID: mdl-24286136

18.

Autoimmunity stimulated by adoptively transferred dendritic cells is initiated by both alphabeta and gammadelta T cells but does not require MyD88 signaling.

Martin, David A; Zhang, Kang; Kenkel, Justin; Hughes, Grant; Clark, Edward; Davidson, Anne; Elkon, Keith B.

J Immunol; 179(9): 5819-28, 2007 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-17947655

19.

Innate and adaptive immune response to apoptotic cells.

Peng, Yufeng; Martin, David A; Kenkel, Justin; Zhang, Kang; Ogden, Carol Anne; Elkon, Keith B.

J Autoimmun; 29(4): 303-9, 2007 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-17888627

20.

Anti-IL-17 receptor antibody AMG 827 leads to rapid clinical response in subjects with moderate to severe psoriasis: results from a phase I, randomized, placebo-controlled trial.

Papp, Kim A; Reid, Cathy; Foley, Peter; Sinclair, Rod; Salinger, David H; Williams, Gary; Dong, Hua; Krueger, James G; Russell, Chris B; Martin, David A.

J Invest Dermatol; 132(10): 2466-2469, 2012 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-22622425

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