Pesquisa | Biblioteca Virtual em Saúde

1.

Applications of Immunogenomics to Cancer.

Liu, X Shirley; Mardis, Elaine R.

Cell; 168(4): 600-612, 2017 02 09.

Artigo em Inglês | MEDLINE | ID: mdl-28187283

2.

The next-generation sequencing revolution and its impact on genomics.

Koboldt, Daniel C; Steinberg, Karyn Meltz; Larson, David E; Wilson, Richard K; Mardis, Elaine R.

Cell; 155(1): 27-38, 2013 Sep 26.

Artigo em Inglês | MEDLINE | ID: mdl-24074859

3.

Genomic landscape of non-small cell lung cancer in smokers and never-smokers.

Govindan, Ramaswamy; Ding, Li; Griffith, Malachi; Subramanian, Janakiraman; Dees, Nathan D; Kanchi, Krishna L; Maher, Christopher A; Fulton, Robert; Fulton, Lucinda; Wallis, John; Chen, Ken; Walker, Jason; McDonald, Sandra; Bose, Ron; Ornitz, David; Xiong, Donghai; You, Ming; Dooling, David J; Watson, Mark; Mardis, Elaine R; Wilson, Richard K.

Cell; 150(6): 1121-34, 2012 Sep 14.

Artigo em Inglês | MEDLINE | ID: mdl-22980976

4.

A sequence motif within chromatin entry sites directs MSL establishment on the Drosophila X chromosome.

Alekseyenko, Artyom A; Peng, Shouyong; Larschan, Erica; Gorchakov, Andrey A; Lee, Ok-Kyung; Kharchenko, Peter; McGrath, Sean D; Wang, Charlotte I; Mardis, Elaine R; Park, Peter J; Kuroda, Mitzi I.

Cell; 134(4): 599-609, 2008 Aug 22.

Artigo em Inglês | MEDLINE | ID: mdl-18724933

5.

Orthotopic patient-derived xenografts of paediatric solid tumours.

Stewart, Elizabeth; Federico, Sara M; Chen, Xiang; Shelat, Anang A; Bradley, Cori; Gordon, Brittney; Karlstrom, Asa; Twarog, Nathaniel R; Clay, Michael R; Bahrami, Armita; Freeman, Burgess B; Xu, Beisi; Zhou, Xin; Wu, Jianrong; Honnell, Victoria; Ocarz, Monica; Blankenship, Kaley; Dapper, Jason; Mardis, Elaine R; Wilson, Richard K; Downing, James; Zhang, Jinghui; Easton, John; Pappo, Alberto; Dyer, Michael A.

Nature; 549(7670): 96-100, 2017 09 07.

Artigo em Inglês | MEDLINE | ID: mdl-28854174

6.

Immunological ignorance is an enabling feature of the oligo-clonal T cell response to melanoma neoantigens.

Linette, Gerald P; Becker-Hapak, Michelle; Skidmore, Zachary L; Baroja, Miren Lorea; Xu, Chong; Hundal, Jasreet; Spencer, David H; Fu, Weixuan; Cummins, Casey; Robnett, Maya; Kaabinejadian, Saghar; Hildebrand, William H; Magrini, Vincent; Demeter, Ryan; Krupnick, Alexander S; Griffith, Obi L; Griffith, Malachi; Mardis, Elaine R; Carreno, Beatriz M.

Proc Natl Acad Sci U S A; 116(47): 23662-23670, 2019 Nov 19.

Artigo em Inglês | MEDLINE | ID: mdl-31685621

7.

Role of TP53 mutations in the origin and evolution of therapy-related acute myeloid leukaemia.

Wong, Terrence N; Ramsingh, Giridharan; Young, Andrew L; Miller, Christopher A; Touma, Waseem; Welch, John S; Lamprecht, Tamara L; Shen, Dong; Hundal, Jasreet; Fulton, Robert S; Heath, Sharon; Baty, Jack D; Klco, Jeffery M; Ding, Li; Mardis, Elaine R; Westervelt, Peter; DiPersio, John F; Walter, Matthew J; Graubert, Timothy A; Ley, Timothy J; Druley, Todd; Link, Daniel C; Wilson, Richard K.

Nature; 518(7540): 552-555, 2015 Feb 26.

Artigo em Inglês | MEDLINE | ID: mdl-25487151

8.

Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor.

Juric, Dejan; Castel, Pau; Griffith, Malachi; Griffith, Obi L; Won, Helen H; Ellis, Haley; Ebbesen, Saya H; Ainscough, Benjamin J; Ramu, Avinash; Iyer, Gopa; Shah, Ronak H; Huynh, Tiffany; Mino-Kenudson, Mari; Sgroi, Dennis; Isakoff, Steven; Thabet, Ashraf; Elamine, Leila; Solit, David B; Lowe, Scott W; Quadt, Cornelia; Peters, Malte; Derti, Adnan; Schegel, Robert; Huang, Alan; Mardis, Elaine R; Berger, Michael F; Baselga, José; Scaltriti, Maurizio.

Nature; 518(7538): 240-4, 2015 Feb 12.

Artigo em Inglês | MEDLINE | ID: mdl-25409150

9.

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens.

Gubin, Matthew M; Zhang, Xiuli; Schuster, Heiko; Caron, Etienne; Ward, Jeffrey P; Noguchi, Takuro; Ivanova, Yulia; Hundal, Jasreet; Arthur, Cora D; Krebber, Willem-Jan; Mulder, Gwenn E; Toebes, Mireille; Vesely, Matthew D; Lam, Samuel S K; Korman, Alan J; Allison, James P; Freeman, Gordon J; Sharpe, Arlene H; Pearce, Erika L; Schumacher, Ton N; Aebersold, Ruedi; Rammensee, Hans-Georg; Melief, Cornelis J M; Mardis, Elaine R; Gillanders, William E; Artyomov, Maxim N; Schreiber, Robert D.

Nature; 515(7528): 577-81, 2014 Nov 27.

Artigo em Inglês | MEDLINE | ID: mdl-25428507

10.

C11orf95-RELA fusions drive oncogenic NF-κB signalling in ependymoma.

Parker, Matthew; Mohankumar, Kumarasamypet M; Punchihewa, Chandanamali; Weinlich, Ricardo; Dalton, James D; Li, Yongjin; Lee, Ryan; Tatevossian, Ruth G; Phoenix, Timothy N; Thiruvenkatam, Radhika; White, Elsie; Tang, Bo; Orisme, Wilda; Gupta, Kirti; Rusch, Michael; Chen, Xiang; Li, Yuxin; Nagahawhatte, Panduka; Hedlund, Erin; Finkelstein, David; Wu, Gang; Shurtleff, Sheila; Easton, John; Boggs, Kristy; Yergeau, Donald; Vadodaria, Bhavin; Mulder, Heather L; Becksfort, Jared; Becksford, Jared; Gupta, Pankaj; Huether, Robert; Ma, Jing; Song, Guangchun; Gajjar, Amar; Merchant, Thomas; Boop, Frederick; Smith, Amy A; Ding, Li; Lu, Charles; Ochoa, Kerri; Zhao, David; Fulton, Robert S; Fulton, Lucinda L; Mardis, Elaine R; Wilson, Richard K; Downing, James R; Green, Douglas R; Zhang, Jinghui; Ellison, David W; Gilbertson, Richard J.

Nature; 506(7489): 451-5, 2014 Feb 27.

Artigo em Inglês | MEDLINE | ID: mdl-24553141

11.

Research-based PAM50 signature and long-term breast cancer survival.

Pu, Minya; Messer, Karen; Davies, Sherri R; Vickery, Tammi L; Pittman, Emily; Parker, Barbara A; Ellis, Matthew J; Flatt, Shirley W; Marinac, Catherine R; Nelson, Sandahl H; Mardis, Elaine R; Pierce, John P; Natarajan, Loki.

Breast Cancer Res Treat; 2019 Sep 21.

Artigo em Inglês | MEDLINE | ID: mdl-31542876

12.

No evidence that G6PD deficiency affects the efficacy or safety of daunorubicin in acute lymphoblastic leukemia induction therapy.

Robinson, Katherine M; Yang, Wenjian; Karol, Seth E; Kornegay, Nancy; Jay, Dennis; Cheng, Cheng; Choi, John K; Campana, Dario; Pui, Ching-Hon; Wood, Brent; Borowitz, Michael J; Gastier-Foster, Julie; Larsen, Eric C; Winick, Naomi; Carroll, William L; Loh, Mignon L; Raetz, Elizabeth A; Hunger, Stephen P; Devidas, Meenakshi; Mardis, Elaine R; Fulton, Robert S; Relling, Mary V; Jeha, Sima.

Pediatr Blood Cancer; 66(6): e27681, 2019 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-30848065

13.

Integrated Analysis of RNA and DNA from the Phase III Trial CALGB 40601 Identifies Predictors of Response to Trastuzumab-Based Neoadjuvant Chemotherapy in HER2-Positive Breast Cancer.

Tanioka, Maki; Fan, Cheng; Parker, Joel S; Hoadley, Katherine A; Hu, Zhiyuan; Li, Yan; Hyslop, Terry M; Pitcher, Brandelyn N; Soloway, Matthew G; Spears, Patricia A; Henry, Lynn N; Tolaney, Sara; Dang, Chau T; Krop, Ian E; Harris, Lyndsay N; Berry, Donald A; Mardis, Elaine R; Winer, Eric P; Hudis, Clifford A; Carey, Lisa A; Perou, Charles M.

Clin Cancer Res; 24(21): 5292-5304, 2018 Nov 01.

Artigo em Inglês | MEDLINE | ID: mdl-30037817

14.

Integrated genomic characterization of endometrial carcinoma.

Kandoth, Cyriac; Schultz, Nikolaus; Cherniack, Andrew D; Akbani, Rehan; Liu, Yuexin; Shen, Hui; Robertson, A Gordon; Pashtan, Itai; Shen, Ronglai; Benz, Christopher C; Yau, Christina; Laird, Peter W; Ding, Li; Zhang, Wei; Mills, Gordon B; Kucherlapati, Raju; Mardis, Elaine R; Levine, Douglas A.

Nature; 497(7447): 67-73, 2013 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-23636398

15.

Germline Mutations in Predisposition Genes in Pediatric Cancer.

Zhang, Jinghui; Walsh, Michael F; Wu, Gang; Edmonson, Michael N; Gruber, Tanja A; Easton, John; Hedges, Dale; Ma, Xiaotu; Zhou, Xin; Yergeau, Donald A; Wilkinson, Mark R; Vadodaria, Bhavin; Chen, Xiang; McGee, Rose B; Hines-Dowell, Stacy; Nuccio, Regina; Quinn, Emily; Shurtleff, Sheila A; Rusch, Michael; Patel, Aman; Becksfort, Jared B; Wang, Shuoguo; Weaver, Meaghann S; Ding, Li; Mardis, Elaine R; Wilson, Richard K; Gajjar, Amar; Ellison, David W; Pappo, Alberto S; Pui, Ching-Hon; Nichols, Kim E; Downing, James R.

N Engl J Med; 373(24): 2336-2346, 2015 Dec 10.

Artigo em Inglês | MEDLINE | ID: mdl-26580448

16.

INTEGRATE-neo: a pipeline for personalized gene fusion neoantigen discovery.

Zhang, Jin; Mardis, Elaine R; Maher, Christopher A.

Bioinformatics; 33(4): 555-557, 2017 02 15.

Artigo em Inglês | MEDLINE | ID: mdl-27797777

17.

Rapid expansion of preexisting nonleukemic hematopoietic clones frequently follows induction therapy for de novo AML.

Wong, Terrence N; Miller, Christopher A; Klco, Jeffery M; Petti, Allegra; Demeter, Ryan; Helton, Nichole M; Li, Tiandao; Fulton, Robert S; Heath, Sharon E; Mardis, Elaine R; Westervelt, Peter; DiPersio, John F; Walter, Matthew J; Welch, John S; Graubert, Timothy A; Wilson, Richard K; Ley, Timothy J; Link, Daniel C.

Blood; 127(7): 893-7, 2016 Feb 18.

Artigo em Inglês | MEDLINE | ID: mdl-26631115

18.

Where Next for Genetics and Genomics?

Tyler-Smith, Chris; Yang, Huanming; Landweber, Laura F; Dunham, Ian; Knoppers, Bartha M; Donnelly, Peter; Mardis, Elaine R; Snyder, Michael; McVean, Gil.

PLoS Biol; 13(7): e1002216, 2015 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-26225775

19.

Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting.

Matsushita, Hirokazu; Vesely, Matthew D; Koboldt, Daniel C; Rickert, Charles G; Uppaluri, Ravindra; Magrini, Vincent J; Arthur, Cora D; White, J Michael; Chen, Yee-Shiuan; Shea, Lauren K; Hundal, Jasreet; Wendl, Michael C; Demeter, Ryan; Wylie, Todd; Allison, James P; Smyth, Mark J; Old, Lloyd J; Mardis, Elaine R; Schreiber, Robert D.

Nature; 482(7385): 400-4, 2012 Feb 08.

Artigo em Inglês | MEDLINE | ID: mdl-22318521

20.

A novel retinoblastoma therapy from genomic and epigenetic analyses.

Zhang, Jinghui; Benavente, Claudia A; McEvoy, Justina; Flores-Otero, Jacqueline; Ding, Li; Chen, Xiang; Ulyanov, Anatoly; Wu, Gang; Wilson, Matthew; Wang, Jianmin; Brennan, Rachel; Rusch, Michael; Manning, Amity L; Ma, Jing; Easton, John; Shurtleff, Sheila; Mullighan, Charles; Pounds, Stanley; Mukatira, Suraj; Gupta, Pankaj; Neale, Geoff; Zhao, David; Lu, Charles; Fulton, Robert S; Fulton, Lucinda L; Hong, Xin; Dooling, David J; Ochoa, Kerri; Naeve, Clayton; Dyson, Nicholas J; Mardis, Elaine R; Bahrami, Armita; Ellison, David; Wilson, Richard K; Downing, James R; Dyer, Michael A.

Nature; 481(7381): 329-34, 2012 Jan 11.

Artigo em Inglês | MEDLINE | ID: mdl-22237022

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