Pesquisa | Biblioteca Virtual em Saúde

1.

Gene Discovery for Complex Traits: Lessons from Africa.

McClellan, Jon M; Lehner, Thomas; King, Mary-Claire.

Cell; 171(2): 261-264, 2017 Oct 05.

Artigo em Inglês | MEDLINE | ID: mdl-28985555

2.

From genetics to biology: advancing mental health research in the Genomics ERA.

Alexander Arguello, P; Addington, Anjené; Borja, Susan; Brady, Linda; Dutka, Tara; Gitik, Miri; Koester, Susan; Meinecke, Douglas; Merikangas, Kathleen; McMahon, Francis J; Panchision, David; Senthil, Geetha; Lehner, Thomas.

Mol Psychiatry; 24(11): 1576-1582, 2019 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-31164699

3.

The Effect of Cellular Stress on T and B Cell Memory Pathways in Immunized and Unimmunized BALB/c Mice.

Wang, Yufei; Rahman, Durdana; Mistry, Mukesh; Lehner, Thomas.

J Biol Chem; 291(39): 20707-17, 2016 09 23.

Artigo em Inglês | MEDLINE | ID: mdl-27502276

4.

Stress-activated Dendritic Cells (DC) Induce Dual Interleukin (IL)-15- and IL1ß-mediated Pathways, Which May Elicit CD4+ Memory T Cells and Interferon (IFN)-stimulated Genes.

Wang, Yufei; Lavender, Paul; Watson, Julie; Arno, Matthew; Lehner, Thomas.

J Biol Chem; 290(25): 15595-609, 2015 Jun 19.

Artigo em Inglês | MEDLINE | ID: mdl-25907558

5.

A mechanism for controlled access to GWAS data: experience of the GAIN Data Access Committee.

Ramos, Erin M; Din-Lovinescu, Corina; Bookman, Ebony B; McNeil, Lisa J; Baker, Carl C; Godynskiy, Georgy; Harris, Emily L; Lehner, Thomas; McKeon, Catherine; Moss, Joel; Starks, Vaurice L; Sherry, Stephen T; Manolio, Teri A; Rodriguez, Laura Lyman.

Am J Hum Genet; 92(4): 479-88, 2013 Apr 04.

Artigo em Inglês | MEDLINE | ID: mdl-23561843

6.

Effect of vaginal immunization with HIVgp140 and HSP70 on HIV-1 replication and innate and T cell adaptive immunity in women.

Lewis, David J M; Wang, Yufei; Huo, Zhiming; Giemza, Raphaela; Babaahmady, Kaboutar; Rahman, Durdana; Shattock, Robin J; Singh, Mahavir; Lehner, Thomas.

J Virol; 88(20): 11648-57, 2014 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-25008917

7.

The value of regenotyping older linkage data sets with denser marker panels.

Vieland, Veronica J; Walters, Kimberly A; Azaro, Marco; Brzustowicz, Linda M; Lehner, Thomas.

Hum Hered; 78(1): 9-16, 2014.

Artigo em Inglês | MEDLINE | ID: mdl-24969307

8.

A comparative study of stress-mediated immunological functions with the adjuvanticity of alum.

Wang, Yufei; Rahman, Durdana; Lehner, Thomas.

J Biol Chem; 287(21): 17152-60, 2012 May 18.

Artigo em Inglês | MEDLINE | ID: mdl-22474329

9.

B-cell agonists up-regulate AID and APOBEC3G deaminases, which induce IgA and IgG class antibodies and anti-viral function.

Seidl, Thomas; Whittall, Trevor; Babaahmady, Kaboutar; Lehner, Thomas.

Immunology; 135(3): 207-15, 2012 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-22044427

10.

Immunization with recombinant macaque major histocompatibility complex class I and II and human immunodeficiency virus gp140 inhibits simian-human immunodeficiency virus infection in macaques.

Yang, Gui-Bo; Wang, Yufei; Babaahmady, Kaboutar; Schøller, Jørgen; Rahman, Durdana; Bunnik, Evelien; Spallek, Ralf; Zong, Chun-Miao; Duan, Jia-Zhong; Qin, Chuan; Jiang, Hong; Singh, Mahavir; Vaughan, Robert; Bergmeier, Lesley A; Schuitemaker, Hanneke; Shao, Yiming; Lehner, Thomas.

J Gen Virol; 93(Pt 7): 1506-18, 2012 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-22492918

11.

Immunization with recombinant HLA classes I and II, HIV-1 gp140, and SIV p27 elicits protection against heterologous SHIV infection in rhesus macaques.

Mörner, Andreas; Jansson, Marianne; Bunnik, Evelien M; Schøller, Jørgen; Vaughan, Robert; Wang, Yufei; Montefiori, David C; Otting, Nel; Bontrop, Ronald; Bergmeier, Lesley A; Singh, Mahavir; Wyatt, Richard T; Schuitemaker, Hanneke; Biberfeld, Gunnel; Thorstensson, Rigmor; Lehner, Thomas.

J Virol; 85(13): 6442-52, 2011 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-21490092

12.

Stress-activated dendritic cells interact with CD4+ T cells to elicit homeostatic memory.

Wang, Yufei; Seidl, Thomas; Whittall, Trevor; Babaahmady, Kaboutar; Lehner, Thomas.

Eur J Immunol; 40(6): 1628-38, 2010 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-20391436

13.

Cytoskeletal proteins bound to heat-shock protein 70 may elicit resistance to simian immunodeficiency virus infection of CD4(+) T cells.

Bergmeier, Lesley A; Babaahmady, Kaboutar; Pido-Lopez, Jeffrey; Heesom, Kate J; Kelly, Charles G; Lehner, Thomas.

Immunology; 129(4): 506-15, 2010 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-20002211

14.

The effect of allogeneic in vitro stimulation and in vivo immunization on memory CD4(+) T-cell APOBEC3G expression and HIV-1 infectivity.

Pido-Lopez, Jeffrey; Jeffrey, Pido-Lopez; Wang, Yufei; Seidl, Thomas; Babaahmady, Kaboutar; Vaughan, Robert; Lehner, Thomas.

Eur J Immunol; 39(7): 1956-65, 2009 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-19585516

15.

The Netherlands Twin Register biobank: a resource for genetic epidemiological studies.

Willemsen, Gonneke; de Geus, Eco J C; Bartels, Meike; van Beijsterveldt, C E M Toos; Brooks, Andy I; Estourgie-van Burk, G Frederique; Fugman, Douglas A; Hoekstra, Chantal; Hottenga, Jouke-Jan; Kluft, Kees; Meijer, Piet; Montgomery, Grant W; Rizzu, Patrizia; Sondervan, David; Smit, August B; Spijker, Sabine; Suchiman, H Eka D; Tischfield, Jay A; Lehner, Thomas; Slagboom, P Eline; Boomsma, Dorret I.

Twin Res Hum Genet; 13(3): 231-45, 2010 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-20477721

16.

Interaction between the serotonin transporter gene (5-HTTLPR), stressful life events, and risk of depression: a meta-analysis.

Risch, Neil; Herrell, Richard; Lehner, Thomas; Liang, Kung-Yee; Eaves, Lindon; Hoh, Josephine; Griem, Andrea; Kovacs, Maria; Ott, Jurg; Merikangas, Kathleen Ries.

JAMA; 301(23): 2462-71, 2009 Jun 17.

Artigo em Inglês | MEDLINE | ID: mdl-19531786

17.

Schizophrenia research in the era of Team Science and big data.

Senthil, Geetha; Lehner, Thomas.

Schizophr Res; 2019 Jul 16.

Artigo em Inglês | MEDLINE | ID: mdl-31324441

18.

A framework for the investigation of rare genetic disorders in neuropsychiatry.

Sanders, Stephan J; Sahin, Mustafa; Hostyk, Joseph; Thurm, Audrey; Jacquemont, Sebastien; Avillach, Paul; Douard, Elise; Martin, Christa L; Modi, Meera E; Moreno-De-Luca, Andres; Raznahan, Armin; Anticevic, Alan; Dolmetsch, Ricardo; Feng, Guoping; Geschwind, Daniel H; Glahn, David C; Goldstein, David B; Ledbetter, David H; Mulle, Jennifer G; Pasca, Sergiu P; Samaco, Rodney; Sebat, Jonathan; Pariser, Anne; Lehner, Thomas; Gur, Raquel E; Bearden, Carrie E.

Nat Med; 25(10): 1477-1487, 2019 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-31548702

19.

Special regulatory T cell review: The resurgence of the concept of contrasuppression in immunoregulation.

Lehner, Thomas.

Immunology; 123(1): 40-4, 2008 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-18154618

20.

The Open Translational Science in Schizophrenia (OPTICS) project: an open-science project bringing together Janssen clinical trial and NIMH data.

Wilcox, Marsha A; Savitz, Adam J; Addington, Anjené M; Gray, Gary S; Guinan, Eva C; Jackson, John W; Lehner, Thomas; Normand, Sharon-Lise; Ranu, Hardeep; Senthil, Geetha; Spertus, Jake; Valeri, Linda; Ross, Joseph S.

NPJ Schizophr; 4(1): 14, 2018 Jun 27.

Artigo em Inglês | MEDLINE | ID: mdl-29950580

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