Pesquisa | Biblioteca Virtual em Saúde

1.

S100A4-neutralizing antibody suppresses spontaneous tumor progression, pre-metastatic niche formation and alters T-cell polarization balance.

Grum-Schwensen, Birgitte; Klingelhöfer, Jörg; Beck, Mette; Bonefeld, Charlotte Menné; Hamerlik, Petra; Guldberg, Per; Grigorian, Mariam; Lukanidin, Eugene; Ambartsumian, Noona.

BMC Cancer; 15: 44, 2015 Feb 12.

Artigo em Inglês | MEDLINE | ID: mdl-25884510

2.

Peptide mimetic of the S100A4 protein modulates peripheral nerve regeneration and attenuates the progression of neuropathy in myelin protein P0 null mice.

Moldovan, Mihai; Pinchenko, Volodymyr; Dmytriyeva, Oksana; Pankratova, Stanislava; Fugleholm, Kåre; Klingelhofer, Jorg; Bock, Elisabeth; Berezin, Vladimir; Krarup, Christian; Kiryushko, Darya.

Mol Med; 19: 43-53, 2013 Apr 30.

Artigo em Inglês | MEDLINE | ID: mdl-23508572

3.

Metastasis-inducing S100A4 protein is associated with the disease activity of rheumatoid arthritis.

Oslejsková, Lucie; Grigorian, Mariam; Hulejová, Hana; Vencovsky, Jirí; Pavelka, Karel; Klingelhöfer, Jörg; Gay, Steffen; Neidhart, Michel; Brabcová, Hana; Suchy, David; Senolt, Ladislav.

Rheumatology (Oxford); 48(12): 1590-4, 2009 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-19828600

4.

Molecular mechanisms of Ca(2+) signaling in neurons induced by the S100A4 protein.

Kiryushko, Darya; Novitskaya, Vera; Soroka, Vladislav; Klingelhofer, Jorg; Lukanidin, Eugene; Berezin, Vladimir; Bock, Elisabeth.

Mol Cell Biol; 26(9): 3625-38, 2006 May.

Artigo em Inglês | MEDLINE | ID: mdl-16612001

5.

The Multifaceted S100A4 Protein in Cancer and Inflammation.

Ambartsumian, Noona; Klingelhöfer, Jörg; Grigorian, Mariam.

Methods Mol Biol; 1929: 339-365, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-30710284

6.

The S100A4 Protein Signals through the ErbB4 Receptor to Promote Neuronal Survival.

Pankratova, Stanislava; Klingelhofer, Jorg; Dmytriyeva, Oksana; Owczarek, Sylwia; Renziehausen, Alexander; Syed, Nelofer; Porter, Alexandra E; Dexter, David T; Kiryushko, Darya.

Theranostics; 8(14): 3977-3990, 2018.

Artigo em Inglês | MEDLINE | ID: mdl-30083275

7.

Suppression of tumor development and metastasis formation in mice lacking the S100A4(mts1) gene.

Grum-Schwensen, Birgitte; Klingelhofer, Jörg; Berg, Christian Hededam; El-Naaman, Christina; Grigorian, Mariam; Lukanidin, Eugene; Ambartsumian, Noona.

Cancer Res; 65(9): 3772-80, 2005 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-15867373

8.

Extracellular S100A4(mts1) stimulates invasive growth of mouse endothelial cells and modulates MMP-13 matrix metalloproteinase activity.

Schmidt-Hansen, Birgitte; Ornås, Dorte; Grigorian, Mariam; Klingelhöfer, Jörg; Tulchinsky, Eugene; Lukanidin, Eugene; Ambartsumian, Noona.

Oncogene; 23(32): 5487-95, 2004 Jul 15.

Artigo em Inglês | MEDLINE | ID: mdl-15122322

9.

Dynamic interplay between adhesive and lateral E-cadherin dimers.

Klingelhöfer, Jörg; Laur, Oscar Y; Troyanovsky, Regina B; Troyanovsky, Sergey M.

Mol Cell Biol; 22(21): 7449-58, 2002 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-12370292

10.

Exchange of catenins in cadherin-catenin complex.

Klingelhöfer, Jörg; Troyanovsky, Regina B; Laur, Oscar Y; Troyanovsky, Sergey.

Oncogene; 22(8): 1181-8, 2003 Feb 27.

Artigo em Inglês | MEDLINE | ID: mdl-12606944

11.

In vitro validation of an ultra-sensitive scanning fluorescence microscope for analysis of circulating tumor cells.

Hillig, Thore; Nygaard, Ann-Britt; Nekiunaite, Laura; Klingelhöfer, Jörg; Sölétormos, György.

APMIS; 122(6): 545-51, 2014 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-24164622

12.

A generally applicable translational strategy identifies S100A4 as a candidate gene in allergy.

Bruhn, Sören; Fang, Yu; Barrenäs, Fredrik; Gustafsson, Mika; Zhang, Huan; Konstantinell, Aelita; Krönke, Andrea; Sönnichsen, Birte; Bresnick, Anne; Dulyaninova, Natalya; Wang, Hui; Zhao, Yelin; Klingelhöfer, Jörg; Ambartsumian, Noona; Beck, Mette K; Nestor, Colm; Bona, Elsa; Xiang, Zou; Benson, Mikael.

Sci Transl Med; 6(218): 218ra4, 2014 Jan 08.

Artigo em Inglês | MEDLINE | ID: mdl-24401939

13.

Anti-S100A4 antibody suppresses metastasis formation by blocking stroma cell invasion.

Klingelhöfer, Jörg; Grum-Schwensen, Birgitte; Beck, Mette K; Knudsen, Rikke Stagaard Petersen; Grigorian, Mariam; Lukanidin, Eugene; Ambartsumian, Noona.

Neoplasia; 14(12): 1260-8, 2012 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-23308057

14.

α-Catenin contributes to the strength of E-cadherin-p120 interactions.

Troyanovsky, Regina B; Klingelhöfer, Jörg; Troyanovsky, Sergey M.

Mol Biol Cell; 22(22): 4247-55, 2011 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-21937720

15.

Role of fibulin-5 in metastatic organ colonization.

Møller, Henrik Devitt; Ralfkjær, Ulrik; Cremers, Natascha; Frankel, Mika; Pedersen, Rune Troelsgaard; Klingelhöfer, Jörg; Yanagisawa, Hiromi; Grigorian, Mariam; Guldberg, Per; Sleeman, Jonathan; Lukanidin, Eugene; Ambartsumian, Noona.

Mol Cancer Res; 9(5): 553-63, 2011 May.

Artigo em Inglês | MEDLINE | ID: mdl-21454378

16.

Lung metastasis fails in MMTV-PyMT oncomice lacking S100A4 due to a T-cell deficiency in primary tumors.

Grum-Schwensen, Birgitte; Klingelhöfer, Jörg; Grigorian, Mariam; Almholt, Kasper; Nielsen, Boye Schnack; Lukanidin, Eugene; Ambartsumian, Noona.

Cancer Res; 70(3): 936-47, 2010 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-20103644

17.

Metastasis-inducing S100A4 and RANTES cooperate in promoting tumor progression in mice.

Forst, Birgitte; Hansen, Matilde Thye; Klingelhöfer, Jörg; Møller, Henrik Devitt; Nielsen, Gitte Helle; Grum-Schwensen, Birgitte; Ambartsumian, Noona; Lukanidin, Eugene; Grigorian, Mariam.

PLoS One; 5(4): e10374, 2010 Apr 28.

Artigo em Inglês | MEDLINE | ID: mdl-20442771

18.

Epidermal growth factor receptor ligands as new extracellular targets for the metastasis-promoting S100A4 protein.

Klingelhöfer, Jörg; Møller, Henrik D; Sumer, Eren U; Berg, Christian H; Poulsen, Maria; Kiryushko, Darya; Soroka, Vladislav; Ambartsumian, Noona; Grigorian, Mariam; Lukanidin, Eugene M.

FEBS J; 276(20): 5936-48, 2009 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-19740107

19.

Expression of S100A4 by a variety of cell types present in the tumor microenvironment of human breast cancer.

Cabezón, Teresa; Celis, Julio E; Skibshøj, Inge; Klingelhöfer, Jörg; Grigorian, Mariam; Gromov, Pavel; Rank, Fritz; Myklebust, June Helen; Maelandsmo, Gunhild M; Lukanidin, Eugene; Ambartsumian, Noona.

Int J Cancer; 121(7): 1433-44, 2007 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-17565747

20.

Up-regulation of metastasis-promoting S100A4 (Mts-1) in rheumatoid arthritis: putative involvement in the pathogenesis of rheumatoid arthritis.

Klingelhöfer, Jörg; Senolt, Ladislav; Baslund, Bo; Nielsen, Gitte Helle; Skibshøj, Inge; Pavelka, Karel; Neidhart, Michel; Gay, Steffen; Ambartsumian, Noona; Hansen, Birgitte Schmidt; Petersen, Jørgen; Lukanidin, Eugene; Grigorian, Mariam.

Arthritis Rheum; 56(3): 779-89, 2007 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-17328050

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