Pesquisa | Biblioteca Virtual em Saúde

1.

PU.1 controls fibroblast polarization and tissue fibrosis.

Wohlfahrt, Thomas; Rauber, Simon; Uebe, Steffen; Luber, Markus; Soare, Alina; Ekici, Arif; Weber, Stefanie; Matei, Alexandru-Emil; Chen, Chih-Wei; Maier, Christiane; Karouzakis, Emmanuel; Kiener, Hans P; Pachera, Elena; Dees, Clara; Beyer, Christian; Daniel, Christoph; Gelse, Kolja; Kremer, Andreas E; Naschberger, Elisabeth; Stürzl, Michael; Butter, Falk; Sticherling, Michael; Finotto, Susetta; Kreuter, Alexander; Kaplan, Mark H; Jüngel, Astrid; Gay, Steffen; Nutt, Stephen L; Boykin, David W; Poon, Gregory M K; Distler, Oliver; Schett, Georg; Distler, Jörg H W; Ramming, Andreas.

Nature; 566(7744): 344-349, 2019 02.

Artigo em Inglês | MEDLINE | ID: mdl-30700907

2.

FOXO3 is involved in the tumor necrosis factor-driven inflammatory response in fibroblast-like synoviocytes.

Brandstetter, Bernhard; Dalwigk, Karolina; Platzer, Alexander; Niederreiter, Birgit; Kartnig, Felix; Fischer, Anita; Vladimer, Gregory I; Byrne, Ruth A; Sevelda, Florian; Holinka, Johannes; Pap, Thomas; Steiner, Günter; Superti-Furga, Giulio; Smolen, Josef S; Kiener, Hans P; Karonitsch, Thomas.

Lab Invest; 99(5): 648-658, 2019 May.

Artigo em Inglês | MEDLINE | ID: mdl-30679758

3.

Targeted inhibition of Janus kinases abates interfon gamma-induced invasive behaviour of fibroblast-like synoviocytes.

Karonitsch, Thomas; Beckmann, Denise; Dalwigk, Karolina; Niederreiter, Birgit; Studenic, Paul; Byrne, Ruth A; Holinka, Johannes; Sevelda, Florian; Korb-Pap, Adelheid; Steiner, Günter; Smolen, Josef S; Pap, Thomas; Kiener, Hans P.

Rheumatology (Oxford); 57(3): 572-577, 2018 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-29228301

4.

Relation of Nailfold Capillaries and Autoantibodies to Mortality in Patients With Raynaud Phenomenon.

Mueller, Markus; Gschwandtner, Michael E; Gamper, Jutta; Giurgea, Georgiana-Aura; Charwat-Resl, Silvia; Kiener, Hans P; Smolen, Josef S; Perkmann, Thomas; Koppensteiner, Renate; Schlager, Oliver.

Circulation; 133(5): 509-17, 2016 Feb 02.

Artigo em Inglês | MEDLINE | ID: mdl-26733605

5.

MicroRNA-146a governs fibroblast activation and joint pathology in arthritis.

Saferding, Victoria; Puchner, Antonia; Goncalves-Alves, Eliana; Hofmann, Melanie; Bonelli, Michael; Brunner, Julia S; Sahin, Emine; Niederreiter, Birgit; Hayer, Silvia; Kiener, Hans P; Einwallner, Elisa; Nehmar, Ramzi; Carapito, Raphael; Georgel, Philippe; Koenders, Marije I; Boldin, Mark; Schabbauer, Gernot; Kurowska-Stolarska, Mariola; Steiner, Günter; Smolen, Josef S; Redlich, Kurt; Blüml, Stephan.

J Autoimmun; 82: 74-84, 2017 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-28545737

6.

The RNA-binding protein HuR/ELAVL1 regulates IFN-ß mRNA abundance and the type I IFN response.

Herdy, Barbara; Karonitsch, Thomas; Vladimer, Gregory I; Tan, Chris S H; Stukalov, Alexey; Trefzer, Claudia; Bigenzahn, Johannes W; Theil, Tamara; Holinka, Johannes; Kiener, Hans P; Colinge, Jacques; Bennett, Keiryn L; Superti-Furga, Giulio.

Eur J Immunol; 45(5): 1500-11, 2015 May.

Artigo em Inglês | MEDLINE | ID: mdl-25678110

7.

Interferon signals and monocytic sensitization of the interferon-Î³ signaling pathway in the peripheral blood of patients with rheumatoid arthritis.

Karonitsch, Thomas; von Dalwigk, Karolina; Steiner, Carl W; Blüml, Stephan; Steiner, Günter; Kiener, Hans P; Smolen, Josef S; Aringer, Martin.

Arthritis Rheum; 64(2): 400-8, 2012 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-21953607

8.

Response to Letter Regarding Article, "Relation of Nailfold Capillaries and Autoantibodies to Mortality in Patients With Raynaud Phenomenon".

Schlager, Oliver; Mueller, Markus; Gamper, Jutta; Giurgea, Georgiana-Aura; Charwat-Resl, Silvia; Kiener, Hans P; Smolen, Josef S; Perkmann, Thomas; Koppensteiner, Renate; Gschwandtner, Michael E.

Circulation; 133(22): e669, 2016 May 31.

Artigo em Inglês | MEDLINE | ID: mdl-27245655

9.

Dysbalance of angiogenic and angiostatic mediators in patients with mixed connective tissue disease.

Distler, Jörg H W; Strapatsas, Tobias; Huscher, Dörte; Dees, Clara; Akhmetshina, Alfiya; Kiener, Hans P; Tarner, Ingo H; Maurer, Britta; Walder, Marcel; Michel, Beat; Gay, Steffen; Smolen, Josef S; Müller-Ladner, Ulf; Schett, Georg; Distler, Oliver.

Ann Rheum Dis; 70(7): 1197-202, 2011 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-21622771

10.

Synovial fibroblasts self-direct multicellular lining architecture and synthetic function in three-dimensional organ culture.

Kiener, Hans P; Watts, Gerald F M; Cui, Yajun; Wright, John; Thornhill, Thomas S; Sköld, Markus; Behar, Samuel M; Niederreiter, Birgit; Lu, Jun; Cernadas, Manuela; Coyle, Anthony J; Sims, Gary P; Smolen, Josef; Warman, Matthew L; Brenner, Michael B; Lee, David M.

Arthritis Rheum; 62(3): 742-52, 2010 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-20131230

11.

Cadherin-11 provides specific cellular adhesion between fibroblast-like synoviocytes.

Valencia, Xavier; Higgins, Jonathan M G; Kiener, Hans P; Lee, David M; Podrebarac, Theresa A; Dascher, Christopher C; Watts, Gerald F M; Mizoguchi, Emiko; Simmons, Barry; Patel, Dhavalkumar D; Bhan, Atul K; Brenner, Michael B.

J Exp Med; 200(12): 1673-9, 2004 Dec 20.

Artigo em Inglês | MEDLINE | ID: mdl-15611293

12.

The cadherin-11 cytoplasmic juxtamembrane domain promotes alpha-catenin turnover at adherens junctions and intercellular motility.

Kiener, Hans P; Stipp, Christopher S; Allen, Philip G; Higgins, Jonathan M G; Brenner, Michael B.

Mol Biol Cell; 17(5): 2366-76, 2006 May.

Artigo em Inglês | MEDLINE | ID: mdl-16525026

13.

IRF1 is critical for the TNF-driven interferon response in rheumatoid fibroblast-like synoviocytes : JAKinibs suppress the interferon response in RA-FLSs.

Bonelli, Michael; Dalwigk, Karolina; Platzer, Alexander; Olmos Calvo, Isabel; Hayer, Silvia; Niederreiter, Birgit; Holinka, Johannes; Sevelda, Florian; Pap, Thomas; Steiner, Günter; Superti-Furga, Giulio; Smolen, Josef S; Kiener, Hans P; Karonitsch, Thomas.

Exp Mol Med; 51(7): 75, 2019 Jul 08.

Artigo em Inglês | MEDLINE | ID: mdl-31285419

14.

mTOR Senses Environmental Cues to Shape the Fibroblast-like Synoviocyte Response to Inflammation.

Karonitsch, Thomas; Kandasamy, Richard K; Kartnig, Felix; Herdy, Barbara; Dalwigk, Karolina; Niederreiter, Birgit; Holinka, Johannes; Sevelda, Florian; Windhager, Reinhard; Bilban, Martin; Weichhart, Thomas; Säemann, Marcus; Pap, Thomas; Steiner, Günter; Smolen, Josef S; Kiener, Hans P; Superti-Furga, Giulio.

Cell Rep; 23(7): 2157-2167, 2018 May 15.

Artigo em Inglês | MEDLINE | ID: mdl-29768212

15.

CD55 deposited on synovial collagen fibers protects from immune complex-mediated arthritis.

Karpus, Olga N; Kiener, Hans P; Niederreiter, Birgit; Yilmaz-Elis, A Seda; van der Kaa, Jos; Ramaglia, Valeria; Arens, Ramon; Smolen, Josef S; Botto, Marina; Tak, Paul P; Verbeek, J Sjef; Hamann, Jörg.

Arthritis Res Ther; 17: 6, 2015 Jan 17.

Artigo em Inglês | MEDLINE | ID: mdl-25596646

16.

The synovium as a privileged site in rheumatoid arthritis: cadherin-11 as a dominant player in synovial pathology.

Kiener, Hans P; Karonitsch, Thomas.

Best Pract Res Clin Rheumatol; 25(6): 767-77, 2011 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-22265259

17.

Cadherin 11 promotes invasive behavior of fibroblast-like synoviocytes.

Kiener, Hans P; Niederreiter, Birgit; Lee, David M; Jimenez-Boj, Esther; Smolen, Josef S; Brenner, Michael B.

Arthritis Rheum; 60(5): 1305-10, 2009 May.

Artigo em Inglês | MEDLINE | ID: mdl-19404963

18.

Coexpression of two mesenchymal cadherins, cadherin 11 and N-cadherin, on murine fibroblast-like synoviocytes.

Agarwal, Sandeep K; Lee, David M; Kiener, Hans P; Brenner, Michael B.

Arthritis Rheum; 58(4): 1044-54, 2008 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-18383368

19.

Cadherin-11 in synovial lining formation and pathology in arthritis.

Lee, David M; Kiener, Hans P; Agarwal, Sandeep K; Noss, Erika H; Watts, Gerald F M; Chisaka, Osamu; Takeichi, Masatoshi; Brenner, Michael B.

Science; 315(5814): 1006-10, 2007 Feb 16.

Artigo em Inglês | MEDLINE | ID: mdl-17255475

20.

Cadherin-11 induces rheumatoid arthritis fibroblast-like synoviocytes to form lining layers in vitro.

Kiener, Hans P; Lee, David M; Agarwal, Sandeep K; Brenner, Michael B.

Am J Pathol; 168(5): 1486-99, 2006 May.

Artigo em Inglês | MEDLINE | ID: mdl-16651616

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