Pesquisa | Biblioteca Virtual em Saúde

1.

Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells.

Shi, Wei; Liao, Yang; Willis, Simon N; Taubenheim, Nadine; Inouye, Michael; Tarlinton, David M; Smyth, Gordon K; Hodgkin, Philip D; Nutt, Stephen L; Corcoran, Lynn M.

Nat Immunol; 16(6): 663-73, 2015 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-25894659

2.

Integrating common and rare genetic variation in diverse human populations.

Altshuler, David M; Gibbs, Richard A; Peltonen, Leena; Altshuler, David M; Gibbs, Richard A; Peltonen, Leena; Dermitzakis, Emmanouil; Schaffner, Stephen F; Yu, Fuli; Peltonen, Leena; Dermitzakis, Emmanouil; Bonnen, Penelope E; Altshuler, David M; Gibbs, Richard A; de Bakker, Paul I W; Deloukas, Panos; Gabriel, Stacey B; Gwilliam, Rhian; Hunt, Sarah; Inouye, Michael; Jia, Xiaoming; Palotie, Aarno; Parkin, Melissa; Whittaker, Pamela; Yu, Fuli; Chang, Kyle; Hawes, Alicia; Lewis, Lora R; Ren, Yanru; Wheeler, David; Gibbs, Richard A; Muzny, Donna Marie; Barnes, Chris; Darvishi, Katayoon; Hurles, Matthew; Korn, Joshua M; Kristiansson, Kati; Lee, Charles; McCarrol, Steven A; Nemesh, James; Dermitzakis, Emmanouil; Keinan, Alon; Montgomery, Stephen B; Pollack, Samuela; Price, Alkes L; Soranzo, Nicole; Bonnen, Penelope E; Gibbs, Richard A; Gonzaga-Jauregui, Claudia; Keinan, Alon.

Nature; 467(7311): 52-8, 2010 Sep 02.

Artigo em Inglês | MEDLINE | ID: mdl-20811451

3.

The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.

Mackay, Laura K; Rahimpour, Azad; Ma, Joel Z; Collins, Nicholas; Stock, Angus T; Hafon, Ming-Li; Vega-Ramos, Javier; Lauzurica, Pilar; Mueller, Scott N; Stefanovic, Tijana; Tscharke, David C; Heath, William R; Inouye, Michael; Carbone, Francis R; Gebhardt, Thomas.

Nat Immunol; 14(12): 1294-301, 2013 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-24162776

4.

The diploid genome sequence of an Asian individual.

Wang, Jun; Wang, Wei; Li, Ruiqiang; Li, Yingrui; Tian, Geng; Goodman, Laurie; Fan, Wei; Zhang, Junqing; Li, Jun; Zhang, Juanbin; Guo, Yiran; Feng, Binxiao; Li, Heng; Lu, Yao; Fang, Xiaodong; Liang, Huiqing; Du, Zhenglin; Li, Dong; Zhao, Yiqing; Hu, Yujie; Yang, Zhenzhen; Zheng, Hancheng; Hellmann, Ines; Inouye, Michael; Pool, John; Yi, Xin; Zhao, Jing; Duan, Jinjie; Zhou, Yan; Qin, Junjie; Ma, Lijia; Li, Guoqing; Yang, Zhentao; Zhang, Guojie; Yang, Bin; Yu, Chang; Liang, Fang; Li, Wenjie; Li, Shaochuan; Li, Dawei; Ni, Peixiang; Ruan, Jue; Li, Qibin; Zhu, Hongmei; Liu, Dongyuan; Lu, Zhike; Li, Ning; Guo, Guangwu; Zhang, Jianguo; Ye, Jia.

Nature; 456(7218): 60-5, 2008 Nov 06.

Artigo em Inglês | MEDLINE | ID: mdl-18987735

5.

Multivariate Genome-Wide Association Analysis of a Cytokine Network Reveals Variants with Widespread Immune, Haematological, and Cardiometabolic Pleiotropy.

Nath, Artika P; Ritchie, Scott C; Grinberg, Nastasiya F; Tang, Howard Ho-Fung; Huang, Qin Qin; Teo, Shu Mei; Ahola-Olli, Ari V; Würtz, Peter; Havulinna, Aki S; Santalahti, Kristiina; Pitkänen, Niina; Lehtimäki, Terho; Kähönen, Mika; Lyytikäinen, Leo-Pekka; Raitoharju, Emma; Seppälä, Ilkka; Sarin, Antti-Pekka; Ripatti, Samuli; Palotie, Aarno; Perola, Markus; Viikari, Jorma S; Jalkanen, Sirpa; Maksimow, Mikael; Salmi, Marko; Wallace, Chris; Raitakari, Olli T; Salomaa, Veikko; Abraham, Gad; Kettunen, Johannes; Inouye, Michael.

Am J Hum Genet; 2019 Oct 30.

Artigo em Inglês | MEDLINE | ID: mdl-31679650

6.

Towards clinical utility of polygenic risk scores.

Lambert, Samuel A; Abraham, Gad; Inouye, Michael.

Hum Mol Genet; 28(R2): R133-R142, 2019 Nov 21.

Artigo em Inglês | MEDLINE | ID: mdl-31363735

7.

Identification of expression quantitative trait loci associated with schizophrenia and affective disorders in normal brain tissue.

Bhalala, Oneil G; Nath, Artika P; Inouye, Michael; Sibley, Christopher R.

PLoS Genet; 14(8): e1007607, 2018 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-30142156

8.

Power, false discovery rate and Winner's Curse in eQTL studies.

Huang, Qin Qin; Ritchie, Scott C; Brozynska, Marta; Inouye, Michael.

Nucleic Acids Res; 2018 Sep 05.

Artigo em Inglês | MEDLINE | ID: mdl-30189032

9.

Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy.

Byars, Sean G; Huang, Qin Qin; Gray, Lesley-Ann; Bakshi, Andrew; Ripatti, Samuli; Abraham, Gad; Stearns, Stephen C; Inouye, Michael.

PLoS Genet; 13(6): e1006328, 2017 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-28640878

10.

Systems biology and big data in asthma and allergy - recent discoveries and emerging challenges.

Tang, Howard H F; Sly, Peter D; Holt, Patrick G; Holt, Kathryn E; Inouye, Michael.

Eur Respir J; 2019 Oct 16.

Artigo em Inglês | MEDLINE | ID: mdl-31619470

11.

FastSpar: Rapid and scalable correlation estimation for compositional data.

Watts, Stephen C; Ritchie, Scott C; Inouye, Michael; Holt, Kathryn E.

Bioinformatics; 2018 Aug 29.

Artigo em Inglês | MEDLINE | ID: mdl-30169561

12.

FlashPCA2: principal component analysis of Biobank-scale genotype datasets.

Abraham, Gad; Qiu, Yixuan; Inouye, Michael.

Bioinformatics; 33(17): 2776-2778, 2017 Sep 01.

Artigo em Inglês | MEDLINE | ID: mdl-28475694

13.

A genotype calling algorithm for the Illumina BeadArray platform.

Teo, Yik Y; Inouye, Michael; Small, Kerrin S; Gwilliam, Rhian; Deloukas, Panagiotis; Kwiatkowski, Dominic P; Clark, Taane G.

Bioinformatics; 23(20): 2741-6, 2007 Oct 15.

Artigo em Inglês | MEDLINE | ID: mdl-17846035

14.

An exposome perspective: Early-life events and immune development in a changing world.

Renz, Harald; Holt, Patrick G; Inouye, Michael; Logan, Alan C; Prescott, Susan L; Sly, Peter D.

J Allergy Clin Immunol; 140(1): 24-40, 2017 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-28673401

15.

Vitamin D over the first decade and susceptibility to childhood allergy and asthma.

Hollams, Elysia M; Teo, Shu Mei; Kusel, Merci; Holt, Barbara J; Holt, Kathryn E; Inouye, Michael; De Klerk, Nicholas H; Zhang, Guicheng; Sly, Peter D; Hart, Prue H; Holt, Patrick G.

J Allergy Clin Immunol; 139(2): 472-481.e9, 2017 02.

Artigo em Inglês | MEDLINE | ID: mdl-27726947

16.

Genome-Wide Analysis of Genetic Risk Factors for Rheumatic Heart Disease in Aboriginal Australians Provides Support for Pathogenic Molecular Mimicry.

Gray, Lesley-Ann; D'Antoine, Heather A; Tong, Steven Y C; McKinnon, Melita; Bessarab, Dawn; Brown, Ngiare; Reményi, Bo; Steer, Andrew; Syn, Genevieve; Blackwell, Jenefer M; Inouye, Michael; Carapetis, Jonathan R.

J Infect Dis; 216(11): 1460-1470, 2017 Dec 12.

Artigo em Inglês | MEDLINE | ID: mdl-29029143

17.

Accurate and robust genomic prediction of celiac disease using statistical learning.

Abraham, Gad; Tye-Din, Jason A; Bhalala, Oneil G; Kowalczyk, Adam; Zobel, Justin; Inouye, Michael.

PLoS Genet; 10(2): e1004137, 2014 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-24550740

18.

Distribution and medical impact of loss-of-function variants in the Finnish founder population.

Lim, Elaine T; Würtz, Peter; Havulinna, Aki S; Palta, Priit; Tukiainen, Taru; Rehnström, Karola; Esko, Tõnu; Mägi, Reedik; Inouye, Michael; Lappalainen, Tuuli; Chan, Yingleong; Salem, Rany M; Lek, Monkol; Flannick, Jason; Sim, Xueling; Manning, Alisa; Ladenvall, Claes; Bumpstead, Suzannah; Hämäläinen, Eija; Aalto, Kristiina; Maksimow, Mikael; Salmi, Marko; Blankenberg, Stefan; Ardissino, Diego; Shah, Svati; Horne, Benjamin; McPherson, Ruth; Hovingh, Gerald K; Reilly, Muredach P; Watkins, Hugh; Goel, Anuj; Farrall, Martin; Girelli, Domenico; Reiner, Alex P; Stitziel, Nathan O; Kathiresan, Sekar; Gabriel, Stacey; Barrett, Jeffrey C; Lehtimäki, Terho; Laakso, Markku; Groop, Leif; Kaprio, Jaakko; Perola, Markus; McCarthy, Mark I; Boehnke, Michael; Altshuler, David M; Lindgren, Cecilia M; Hirschhorn, Joel N; Metspalu, Andres; Freimer, Nelson B.

PLoS Genet; 10(7): e1004494, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-25078778

19.

Genomic prediction of coronary heart disease.

Abraham, Gad; Havulinna, Aki S; Bhalala, Oneil G; Byars, Sean G; De Livera, Alysha M; Yetukuri, Laxman; Tikkanen, Emmi; Perola, Markus; Schunkert, Heribert; Sijbrands, Eric J; Palotie, Aarno; Samani, Nilesh J; Salomaa, Veikko; Ripatti, Samuli; Inouye, Michael.

Eur Heart J; 37(43): 3267-3278, 2016 11 14.

Artigo em Inglês | MEDLINE | ID: mdl-27655226

20.

Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems.

Shu, Le; Zhao, Yuqi; Kurt, Zeyneb; Byars, Sean Geoffrey; Tukiainen, Taru; Kettunen, Johannes; Orozco, Luz D; Pellegrini, Matteo; Lusis, Aldons J; Ripatti, Samuli; Zhang, Bin; Inouye, Michael; Mäkinen, Ville-Petteri; Yang, Xia.

BMC Genomics; 17(1): 874, 2016 11 04.

Artigo em Inglês | MEDLINE | ID: mdl-27814671

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