Pesquisa | Biblioteca Virtual em Saúde

1.

Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease.

Hernández-Alvarez, María Isabel; Sebastián, David; Vives, Sara; Ivanova, Saska; Bartoccioni, Paola; Kakimoto, Pamela; Plana, Natalia; Veiga, Sónia R; Hernández, Vanessa; Vasconcelos, Nuno; Peddinti, Gopal; Adrover, Anna; Jové, Mariona; Pamplona, Reinald; Gordaliza-Alaguero, Isabel; Calvo, Enrique; Cabré, Noemí; Castro, Rui; Kuzmanic, Antonija; Boutant, Marie; Sala, David; Hyotylainen, Tuulia; Oresic, Matej; Fort, Joana; Errasti-Murugarren, Ekaitz; Rodrígues, Cecilia M P; Orozco, Modesto; Joven, Jorge; Cantó, Carles; Palacin, Manuel; Fernández-Veledo, Sonia; Vendrell, Joan; Zorzano, Antonio.

Cell; 177(4): 881-895.e17, 2019 May 02.

Artigo em Inglês | MEDLINE | ID: mdl-31051106

2.

Human gut microbes impact host serum metabolome and insulin sensitivity.

Pedersen, Helle Krogh; Gudmundsdottir, Valborg; Nielsen, Henrik Bjørn; Hyotylainen, Tuulia; Nielsen, Trine; Jensen, Benjamin A H; Forslund, Kristoffer; Hildebrand, Falk; Prifti, Edi; Falony, Gwen; Le Chatelier, Emmanuelle; Levenez, Florence; Doré, Joel; Mattila, Ismo; Plichta, Damian R; Pöhö, Päivi; Hellgren, Lars I; Arumugam, Manimozhiyan; Sunagawa, Shinichi; Vieira-Silva, Sara; Jørgensen, Torben; Holm, Jacob Bak; Trost, Kajetan; Kristiansen, Karsten; Brix, Susanne; Raes, Jeroen; Wang, Jun; Hansen, Torben; Bork, Peer; Brunak, Søren; Oresic, Matej; Ehrlich, S Dusko; Pedersen, Oluf.

Nature; 535(7612): 376-81, 2016 07 21.

Artigo em Inglês | MEDLINE | ID: mdl-27409811

3.

Circulating metabolites in progression to islet autoimmunity and type 1 diabetes.

Lamichhane, Santosh; Kemppainen, Esko; Trost, Kajetan; Siljander, Heli; Hyöty, Heikki; Ilonen, Jorma; Toppari, Jorma; Veijola, Riitta; Hyötyläinen, Tuulia; Knip, Mikael; Oresic, Matej.

Diabetologia; 62(12): 2287-2297, 2019 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-31444528

4.

Simultaneous determination of perfluoroalkyl substances and bile acids in human serum using ultra-high-performance liquid chromatography-tandem mass spectrometry.

Salihovic, Samira; Dickens, Alex M; Schoultz, Ida; Fart, Frida; Sinisalu, Lisanna; Lindeman, Tuomas; Halfvarson, Jonas; Oresic, Matej; Hyötyläinen, Tuulia.

Anal Bioanal Chem; 2019 Nov 23.

Artigo em Inglês | MEDLINE | ID: mdl-31760452

5.

Effect of perfluorooctanesulfonic acid (PFOS) on the liver lipid metabolism of the developing chicken embryo.

Geng, Dawei; Musse, Ayan Au; Wigh, Viktoria; Carlsson, Cecilia; Engwall, Magnus; Oresic, Matej; Scherbak, Nikolai; Hyötyläinen, Tuulia.

Ecotoxicol Environ Saf; 170: 691-698, 2019 Apr 15.

Artigo em Inglês | MEDLINE | ID: mdl-30580163

6.

Serum, plasma and erythrocyte membrane lipidomes in infants fed formula supplemented with bovine milk fat globule membranes.

Grip, Tove; Dyrlund, Thomas S; Ahonen, Linda; Domellöf, Magnus; Hernell, Olle; Hyötyläinen, Tuulia; Knip, Mikael; Lönnerdal, Bo; Oresic, Matej; Timby, Niklas.

Pediatr Res; 2018 Aug 04.

Artigo em Inglês | MEDLINE | ID: mdl-30120403

7.

Harmonizing lipidomics: NIST interlaboratory comparison exercise for lipidomics using SRM 1950-Metabolites in Frozen Human Plasma.

Bowden, John A; Heckert, Alan; Ulmer, Candice Z; Jones, Christina M; Koelmel, Jeremy P; Abdullah, Laila; Ahonen, Linda; Alnouti, Yazen; Armando, Aaron M; Asara, John M; Bamba, Takeshi; Barr, John R; Bergquist, Jonas; Borchers, Christoph H; Brandsma, Joost; Breitkopf, Susanne B; Cajka, Tomas; Cazenave-Gassiot, Amaury; Checa, Antonio; Cinel, Michelle A; Colas, Romain A; Cremers, Serge; Dennis, Edward A; Evans, James E; Fauland, Alexander; Fiehn, Oliver; Gardner, Michael S; Garrett, Timothy J; Gotlinger, Katherine H; Han, Jun; Huang, Yingying; Neo, Aveline Huipeng; Hyötyläinen, Tuulia; Izumi, Yoshihiro; Jiang, Hongfeng; Jiang, Houli; Jiang, Jiang; Kachman, Maureen; Kiyonami, Reiko; Klavins, Kristaps; Klose, Christian; Köfeler, Harald C; Kolmert, Johan; Koal, Therese; Koster, Grielof; Kuklenyik, Zsuzsanna; Kurland, Irwin J; Leadley, Michael; Lin, Karen; Maddipati, Krishna Rao.

J Lipid Res; 58(12): 2275-2288, 2017 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-28986437

8.

Impaired hepatic lipid synthesis from polyunsaturated fatty acids in TM6SF2 E167K variant carriers with NAFLD.

Luukkonen, Panu K; Zhou, You; Nidhina Haridas, P A; Dwivedi, Om P; Hyötyläinen, Tuulia; Ali, Ashfaq; Juuti, Anne; Leivonen, Marja; Tukiainen, Taru; Ahonen, Linda; Scott, Emma; Palmer, Jeremy M; Arola, Johanna; Orho-Melander, Marju; Vikman, Petter; Anstee, Quentin M; Olkkonen, Vesa M; Oresic, Matej; Groop, Leif; Yki-Järvinen, Hannele.

J Hepatol; 67(1): 128-136, 2017 07.

Artigo em Inglês | MEDLINE | ID: mdl-28235613

9.

Lipidomics in biomedical research-practical considerations.

Hyötyläinen, Tuulia; Ahonen, Linda; Pöhö, Päivi; Oresic, Matej.

Biochim Biophys Acta Mol Cell Biol Lipids; 1862(8): 800-803, 2017 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-28408341

10.

Longitudinal plasma metabolic profiles, infant feeding, and islet autoimmunity in the MIDIA study.

Jørgenrud, Benedicte; Stene, Lars C; Tapia, German; Bøås, Håkon; Pepaj, Milaim; Berg, Jens P; Thorsby, Per M; Oresic, Matej; Hyötyläinen, Tuulia; Rønningen, Kjersti S.

Pediatr Diabetes; 18(2): 111-119, 2017 03.

Artigo em Inglês | MEDLINE | ID: mdl-26791677

11.

Hepatic ceramides dissociate steatosis and insulin resistance in patients with non-alcoholic fatty liver disease.

Luukkonen, Panu K; Zhou, You; Sädevirta, Sanja; Leivonen, Marja; Arola, Johanna; Oresic, Matej; Hyötyläinen, Tuulia; Yki-Järvinen, Hannele.

J Hepatol; 64(5): 1167-1175, 2016 May.

Artigo em Inglês | MEDLINE | ID: mdl-26780287

12.

Noninvasive Detection of Nonalcoholic Steatohepatitis Using Clinical Markers and Circulating Levels of Lipids and Metabolites.

Zhou, You; Oresic, Matej; Leivonen, Marja; Gopalacharyulu, Peddinti; Hyysalo, Jenni; Arola, Johanna; Verrijken, An; Francque, Sven; Van Gaal, Luc; Hyötyläinen, Tuulia; Yki-Järvinen, Hannele.

Clin Gastroenterol Hepatol; 14(10): 1463-1472.e6, 2016 10.

Artigo em Inglês | MEDLINE | ID: mdl-27317851

13.

A Healthy Nordic Diet Alters the Plasma Lipidomic Profile in Adults with Features of Metabolic Syndrome in a Multicenter Randomized Dietary Intervention.

Lankinen, Maria; Schwab, Ursula; Kolehmainen, Marjukka; Paananen, Jussi; Nygren, Heli; Seppänen-Laakso, Tuulikki; Poutanen, Kaisa; Hyötyläinen, Tuulia; Risérus, Ulf; Savolainen, Markku J; Hukkanen, Janne; Brader, Lea; Marklund, Matti; Rosqvist, Fredrik; Hermansen, Kjeld; Cloetens, Lieselotte; Önning, Gunilla; Thorsdottir, Inga; Gunnarsdottir, Ingibjorg; Åkesson, Björn; Dragsted, Lars Ove; Uusitupa, Matti; Oresic, Matej.

J Nutr; 2016 Mar 09.

Artigo em Inglês | MEDLINE | ID: mdl-26962194

14.

Mondo/ChREBP-Mlx-regulated transcriptional network is essential for dietary sugar tolerance in Drosophila.

Havula, Essi; Teesalu, Mari; Hyötyläinen, Tuulia; Seppälä, Heini; Hasygar, Kiran; Auvinen, Petri; Oresic, Matej; Sandmann, Thomas; Hietakangas, Ville.

PLoS Genet; 9(4): e1003438, 2013 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-23593032

15.

Circulating triacylglycerol signatures and insulin sensitivity in NAFLD associated with the E167K variant in TM6SF2.

Zhou, You; Llauradó, Gemma; Oresic, Matej; Hyötyläinen, Tuulia; Orho-Melander, Marju; Yki-Järvinen, Hannele.

J Hepatol; 62(3): 657-63, 2015 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-25457209

16.

Metabolome and fecal microbiota in monozygotic twin pairs discordant for weight: a Big Mac challenge.

Bondia-Pons, Isabel; Maukonen, Johanna; Mattila, Ismo; Rissanen, Aila; Saarela, Maria; Kaprio, Jaakko; Hakkarainen, Antti; Lundbom, Jesper; Lundbom, Nina; Hyötyläinen, Tuulia; Pietiläinen, Kirsi H; Oresic, Matej.

FASEB J; 28(9): 4169-79, 2014 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-24846387

17.

The effect of atorvastatin treatment on serum oxysterol concentrations and cytochrome P450 3A4 activity.

Hukkanen, Janne; Puurunen, Johanna; Hyötyläinen, Tuulia; Savolainen, Markku J; Ruokonen, Aimo; Morin-Papunen, Laure; Oresic, Matej; Piltonen, Terhi; Tapanainen, Juha S.

Br J Clin Pharmacol; 80(3): 473-9, 2015 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-26095142

18.

Methods for characterization of organic compounds in atmospheric aerosol particles.

Parshintsev, Jevgeni; Hyötyläinen, Tuulia.

Anal Bioanal Chem; 407(20): 5877-97, 2015 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-25542579

19.

Optimizing the lipidomics workflow for clinical studies--practical considerations.

Hyötyläinen, Tuulia; Oresic, Matej.

Anal Bioanal Chem; 407(17): 4973-93, 2015 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-25855150

20.

Monounsaturated fatty acids in serum triacylglycerols are associated with response to neoadjuvant chemotherapy in breast cancer patients.

Hilvo, Mika; Gade, Stephan; Hyötyläinen, Tuulia; Nekljudova, Valentina; Seppänen-Laakso, Tuulikki; Sysi-Aho, Marko; Untch, Michael; Huober, Jens; von Minckwitz, Gunter; Denkert, Carsten; Oresic, Matej; Loibl, Sibylle.

Int J Cancer; 134(7): 1725-33, 2014 Apr 01.

Artigo em Inglês | MEDLINE | ID: mdl-24114462

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