Pesquisa | Biblioteca Virtual em Saúde

1.

Genomic CDKN2A/2B deletions in adult Ph⁺ ALL are adverse despite allogeneic stem cell transplantation.

Pfeifer, Heike; Raum, Katharina; Markovic, Sandra; Nowak, Verena; Fey, Stephanie; Obländer, Julia; Pressler, Jovita; Böhm, Verena; Brüggemann, Monika; Wunderle, Lydia; Hüttmann, Andreas; Wäsch, Ralph; Beck, Joachim; Stelljes, Matthias; Viardot, Andreas; Lang, Fabian; Hoelzer, Dieter; Hofmann, Wolf-Karsten; Serve, Hubert; Weiss, Christel; Goekbuget, Nicola; Ottmann, Oliver G; Nowak, Daniel.

Blood; 131(13): 1464-1475, 2018 03 29.

Artigo em Inglês | MEDLINE | ID: mdl-29348129

2.

Baseline and interim PET-based outcome prediction in peripheral T-cell lymphoma: A subgroup analysis of the PETAL trial.

Schmitz, Christine; Rekowski, Jan; Müller, Stefan P; Hertenstein, Bernd; Franzius, Christiane; Ganser, Arnold; Bengel, Frank M; Kroschinsky, Frank; Kotzerke, Jörg; La Rosée, Paul; Freesmeyer, Martin; Hoeffkes, Heinz-Gert; Hertel, Andreas; Behringer, Dirk; Mesters, Rolf; Weckesser, Matthias; Mahlmann, Stefan; Haberkorn, Uwe; Martens, Uwe; Prange-Krex, Gabriele; Brenner, Winfried; Giagounidis, Aristoteles; Moeller, Regina; Runde, Volker; Sandmann, Matthias; Hautzel, Hubertus; Wilop, Stefan; Krohn, Thomas; Dürk, Heinz; Heike, Michael; Alashkar, Ferras; Brinkmann, Marcus; Trenn, Guido; Wacker, Dietmar; Kreisel-Büstgens, Christiane; Bernhard, Helga; Heil, Gerhard; Larisch, Rolf; Kurch, Lars; Jöckel, Karl-Heinz; Hoelzer, Dieter; Klapper, Wolfram; Boellaard, Ronald; Dührsen, Ulrich; Hüttmann, Andreas.

Hematol Oncol; 38(3): 244-256, 2020 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-32067259

3.

Blinatumomab vs historic standard-of-care treatment for minimal residual disease in adults with B-cell precursor acute lymphoblastic leukaemia.

Gökbuget, Nicola; Dombret, Hervé; Giebel, Sebastian; Brüggemann, Monika; Doubek, Michael; Foa, Robin; Hoelzer, Dieter; Kim, Christopher; Martinelli, Giovanni; Parovichnikova, Elena; Maria Ribera, Josep; Schoonen, Marieke; Tuglus, Catherine; Zugmaier, Gerhard; Bassan, Renato.

Eur J Haematol; 104(4): 299-309, 2020 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-31876009

4.

Hematopoietic stem cell involvement in BCR-ABL1-positive ALL as a potential mechanism of resistance to blinatumomab therapy.

Nagel, Inga; Bartels, Marius; Duell, Johannes; Oberg, Hans-Heinrich; Ussat, Sandra; Bruckmueller, Henrike; Ottmann, Oliver; Pfeifer, Heike; Trautmann, Heiko; Gökbuget, Nicola; Caliebe, Almuth; Kabelitz, Dieter; Kneba, Michael; Horst, Heinz-August; Hoelzer, Dieter; Topp, Max S; Cascorbi, Ingolf; Siebert, Reiner; Brüggemann, Monika.

Blood; 130(18): 2027-2031, 2017 11 02.

Artigo em Inglês | MEDLINE | ID: mdl-28827408

5.

Six versus eight doses of rituximab in patients with aggressive B cell lymphoma receiving six cycles of CHOP: results from the "Positron Emission Tomography-Guided Therapy of Aggressive Non-Hodgkin Lymphomas" (PETAL) trial.

Hüttmann, Andreas; Rekowski, Jan; Müller, Stefan P; Hertenstein, Bernd; Franzius, Christiane; Mesters, Rolf; Weckesser, Matthias; Kroschinsky, Frank; Kotzerke, Jörg; Ganser, Arnold; Bengel, Frank M; La Rosée, Paul; Freesmeyer, Martin; Höffkes, Heinz-Gert; Hertel, Andreas; Behringer, Dirk; Prange-Krex, Gabriele; Griesshammer, Martin; Holzinger, Jens; Wilop, Stefan; Krohn, Thomas; Raghavachar, Aruna; Maschmeyer, Georg; Brink, Ingo; Schroers, Roland; Gaska, Tobias; Bernhard, Helga; Giagounidis, Aristoteles; Schütte, Jochen; Dienst, Ariane; Hautzel, Hubertus; Naumann, Ralph; Klein, Alfred; Hahn, Dennis; Pöpperl, Gabriele; Grube, Matthias; Marienhagen, Jörg; Schwarzer, Andreas; Kurch, Lars; Höhler, Thomas; Steiniger, Heike; Nückel, Holger; Südhoff, Thomas; Römer, Wolfgang; Brinkmann, Marcus; Ose, Claudia; Alashkar, Ferras; Schmitz, Christine; Dürig, Jan; Hoelzer, Dieter.

Ann Hematol; 98(4): 897-907, 2019 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-30610279

6.

Dasatinib and low-intensity chemotherapy in elderly patients with Philadelphia chromosome-positive ALL.

Rousselot, Philippe; Coudé, Marie Magdelaine; Gokbuget, Nicola; Gambacorti Passerini, Carlo; Hayette, Sandrine; Cayuela, Jean-Michel; Huguet, Françoise; Leguay, Thibaut; Chevallier, Patrice; Salanoubat, Celia; Bonmati, Caroline; Alexis, Magda; Hunault, Mathilde; Glaisner, Sylvie; Agape, Philippe; Berthou, Christian; Jourdan, Eric; Fernandes, José; Sutton, Laurent; Banos, Anne; Reman, Oumedaly; Lioure, Bruno; Thomas, Xavier; Ifrah, Norbert; Lafage-Pochitaloff, Marina; Bornand, Anne; Morisset, Laure; Robin, Valérie; Pfeifer, Heike; Delannoy, Andre; Ribera, Josep; Bassan, Renato; Delord, Marc; Hoelzer, Dieter; Dombret, Herve; Ottmann, Oliver G.

Blood; 128(6): 774-82, 2016 08 11.

Artigo em Inglês | MEDLINE | ID: mdl-27121472

7.

Loss-of-function but not dominant-negative intragenic IKZF1 deletions are associated with an adverse prognosis in adult BCR-ABL-negative acute lymphoblastic leukemia.

Kobitzsch, Benjamin; Gökbuget, Nicola; Schwartz, Stefan; Reinhardt, Richard; Brüggemann, Monika; Viardot, Andreas; Wäsch, Ralph; Starck, Michael; Thiel, Eckhard; Hoelzer, Dieter; Burmeister, Thomas.

Haematologica; 102(10): 1739-1747, 2017 10.

Artigo em Inglês | MEDLINE | ID: mdl-28751559

8.

Adults with Philadelphia chromosome-like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis.

Herold, Tobias; Schneider, Stephanie; Metzeler, Klaus H; Neumann, Martin; Hartmann, Luise; Roberts, Kathryn G; Konstandin, Nikola P; Greif, Philipp A; Bräundl, Kathrin; Ksienzyk, Bianka; Huk, Natalia; Schneider, Irene; Zellmeier, Evelyn; Jurinovic, Vindi; Mansmann, Ulrich; Hiddemann, Wolfgang; Mullighan, Charles G; Bohlander, Stefan K; Spiekermann, Karsten; Hoelzer, Dieter; Brüggemann, Monika; Baldus, Claudia D; Dreyling, Martin; Gökbuget, Nicola.

Haematologica; 102(1): 130-138, 2017 01.

Artigo em Inglês | MEDLINE | ID: mdl-27561722

9.

Improved outcome of adult Burkitt lymphoma/leukemia with rituximab and chemotherapy: report of a large prospective multicenter trial.

Hoelzer, Dieter; Walewski, Jan; Döhner, Hartmut; Viardot, Andreas; Hiddemann, Wolfgang; Spiekermann, Karsten; Serve, Hubert; Dührsen, Ulrich; Hüttmann, Andreas; Thiel, Eckhard; Dengler, Jolanta; Kneba, Michael; Schaich, Markus; Schmidt-Wolf, Ingo G H; Beck, Joachim; Hertenstein, Bernd; Reichle, Albrecht; Domanska-Czyz, Katarzyna; Fietkau, Rainer; Horst, Heinz-August; Rieder, Harald; Schwartz, Stefan; Burmeister, Thomas; Gökbuget, Nicola.

Blood; 124(26): 3870-9, 2014 Dec 18.

Artigo em Inglês | MEDLINE | ID: mdl-25359988

10.

International reference analysis of outcomes in adults with B-precursor Ph-negative relapsed/refractory acute lymphoblastic leukemia.

Gökbuget, Nicola; Dombret, Hervè; Ribera, Jose-Maria; Fielding, Adele K; Advani, Anjali; Bassan, Renato; Chia, Victoria; Doubek, Michael; Giebel, Sebastian; Hoelzer, Dieter; Ifrah, Norbert; Katz, Aaron; Kelsh, Michael; Martinelli, Giovanni; Morgades, Mireia; O'Brien, Susan; Rowe, Jacob M; Stieglmaier, Julia; Wadleigh, Martha; Kantarjian, Hagop.

Haematologica; 101(12): 1524-1533, 2016 12.

Artigo em Inglês | MEDLINE | ID: mdl-27587380

11.

Entstehung, Entwicklung und Erfolge des Kompetenznetzes Akute und Chronische Leukämien (KNL). / [Leukemia research in Germany: the Competence Network Acute and Chronic Leukemias].

Kossak-Roth, Ute; Saußele, Susanne; Aul, Carlo; Büchner, Thomas; Döhner, Hartmut; Dugas, Martin; Ehninger, Gerhard; Ganser, Arnold; Giagounidis, Aristoteles; Gökbuget, Nicola; Griesshammer, Martin; Hasford, Jörg; Heuser, Michael; Hiddemann, Wolfgang; Hochhaus, Andreas; Hoelzer, Dieter; Niederwieser, Dietger; Reiter, Andreas; Röllig, Christoph; Hehlmann, Rüdiger.

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz; 59(4): 444-53, 2016 Apr.

Artigo em Alemão | MEDLINE | ID: mdl-26979719

12.

Whole-exome sequencing in adult ETP-ALL reveals a high rate of DNMT3A mutations.

Neumann, Martin; Heesch, Sandra; Schlee, Cornelia; Schwartz, Stefan; Gökbuget, Nicola; Hoelzer, Dieter; Konstandin, Nikola P; Ksienzyk, Bianka; Vosberg, Sebastian; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Raff, Thorsten; Brüggemann, Monika; Hofmann, Wolf-Karsten; Hecht, Jochen; Bohlander, Stefan K; Greif, Philipp A; Baldus, Claudia D.

Blood; 121(23): 4749-52, 2013 Jun 06.

Artigo em Inglês | MEDLINE | ID: mdl-23603912

13.

Bendamustine plus rituximab versus CHOP plus rituximab as first-line treatment for patients with indolent and mantle-cell lymphomas: an open-label, multicentre, randomised, phase 3 non-inferiority trial.

Rummel, Mathias J; Niederle, Norbert; Maschmeyer, Georg; Banat, G Andre; von Grünhagen, Ulrich; Losem, Christoph; Kofahl-Krause, Dorothea; Heil, Gerhard; Welslau, Manfred; Balser, Christina; Kaiser, Ulrich; Weidmann, Eckhart; Dürk, Heinz; Ballo, Harald; Stauch, Martina; Roller, Fritz; Barth, Juergen; Hoelzer, Dieter; Hinke, Axel; Brugger, Wolfram.

Lancet; 381(9873): 1203-10, 2013 Apr 06.

Artigo em Inglês | MEDLINE | ID: mdl-23433739

14.

Immunopharmacologic response of patients with B-lineage acute lymphoblastic leukemia to continuous infusion of T cell-engaging CD19/CD3-bispecific BiTE antibody blinatumomab.

Klinger, Matthias; Brandl, Christian; Zugmaier, Gerhard; Hijazi, Youssef; Bargou, Ralf C; Topp, Max S; Gökbuget, Nicola; Neumann, Svenja; Goebeler, Mariele; Viardot, Andreas; Stelljes, Matthias; Brüggemann, Monika; Hoelzer, Dieter; Degenhard, Evelyn; Nagorsen, Dirk; Baeuerle, Patrick A; Wolf, Andreas; Kufer, Peter.

Blood; 119(26): 6226-33, 2012 Jun 28.

Artigo em Inglês | MEDLINE | ID: mdl-22592608

15.

Adult patients with acute lymphoblastic leukemia and molecular failure display a poor prognosis and are candidates for stem cell transplantation and targeted therapies.

Gökbuget, Nicola; Kneba, Michael; Raff, Thorsten; Trautmann, Heiko; Bartram, Claus-Rainer; Arnold, Renate; Fietkau, Rainer; Freund, Mathias; Ganser, Arnold; Ludwig, Wolf-Dieter; Maschmeyer, Georg; Rieder, Harald; Schwartz, Stefan; Serve, Hubert; Thiel, Eckhard; Brüggemann, Monika; Hoelzer, Dieter.

Blood; 120(9): 1868-76, 2012 Aug 30.

Artigo em Inglês | MEDLINE | ID: mdl-22442346

16.

Outcome of relapsed adult lymphoblastic leukemia depends on response to salvage chemotherapy, prognostic factors, and performance of stem cell transplantation.

Gökbuget, Nicola; Stanze, Daniel; Beck, Joachim; Diedrich, Helmut; Horst, Heinz-August; Hüttmann, Andreas; Kobbe, Guido; Kreuzer, Karl-Anton; Leimer, Lothar; Reichle, Albrecht; Schaich, Markus; Schwartz, Stefan; Serve, Hubert; Starck, Michael; Stelljes, Matthias; Stuhlmann, Reingard; Viardot, Andreas; Wendelin, Knut; Freund, Mathias; Hoelzer, Dieter.

Blood; 120(10): 2032-41, 2012 Sep 06.

Artigo em Inglês | MEDLINE | ID: mdl-22493293

17.

Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL.

Topp, Max S; Gökbuget, Nicola; Zugmaier, Gerhard; Degenhard, Evelyn; Goebeler, Marie-Elisabeth; Klinger, Matthias; Neumann, Svenja A; Horst, Heinz A; Raff, Thorsten; Viardot, Andreas; Stelljes, Matthias; Schaich, Markus; Köhne-Volland, Rudolf; Brüggemann, Monika; Ottmann, Oliver G; Burmeister, Thomas; Baeuerle, Patrick A; Nagorsen, Dirk; Schmidt, Margit; Einsele, Hermann; Riethmüller, Gert; Kneba, Michael; Hoelzer, Dieter; Kufer, Peter; Bargou, Ralf C.

Blood; 120(26): 5185-7, 2012 Dec 20.

Artigo em Inglês | MEDLINE | ID: mdl-23024237

18.

Long-term results of a prospective randomized trial evaluating G-CSF priming in intensive induction chemotherapy followed by autologous stem cell transplantation in elderly patients with acute myeloid leukemia.

Bug, Gesine; Koschmieder, Steffen; Krauter, Juergen; Heuser, Michael; Thol, Felicitas; Wiebe, Stefanie; Hofmann, Wolf-Karsten; Klein, Stefan A; Wegener, Gerd; Göhring, Gudrun; Heit, Wolfgang; Hoelzer, Dieter; Ganser, Arnold; Ottmann, Oliver G.

Ann Hematol; 93(2): 193-202, 2014 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-23978944

19.

Targeted therapy with monoclonal antibodies in acute lymphoblastic leukemia.

Hoelzer, Dieter.

Curr Opin Oncol; 25(6): 701-6, 2013 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-24097105

20.

Overexpression of LEF1 predicts unfavorable outcome in adult patients with B-precursor acute lymphoblastic leukemia.

Kühnl, Andrea; Gökbuget, Nicola; Kaiser, Martin; Schlee, Cornelia; Stroux, Andrea; Burmeister, Thomas; Mochmann, Liliana H; Hoelzer, Dieter; Hofmann, Wolf-Karsten; Thiel, Eckhard; Baldus, Claudia D.

Blood; 118(24): 6362-7, 2011 Dec 08.

Artigo em Inglês | MEDLINE | ID: mdl-22010100

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