Pesquisa | Biblioteca Virtual em Saúde

1.

Prognostication of Molecular Relapses after Dasatinib or Nilotinib Discontinuation in Chronic Myeloid Leukemia (CML): A FI-LMC STOP 2G-TKI Study Update.

Rea, Delphine; Nicolini, Franck E; Tulliez, Michel; Rousselot, Philippe; Gardembas, Martine; Etienne, Gabriel; Guilhot, Francois; Guilhot, Joelle; Guerci, Agnès; Escoffre-Barbe, Martine; Legros, Laurence; Villemagne, Bruno; Guillerm, Gaëlle; Noel, Marie-Pierre; Coiteux, Valerie; Pignon, Jean-Michel; Mahon, Francois-Xavier.

Blood; 134(Supplement_1): 30, 2019 Nov 13.

Artigo em Inglês | MEDLINE | ID: mdl-31724000

2.

Low-dose tyrosine kinase inhibitors before treatment discontinuation do not impair treatment-free remission in chronic myeloid leukemia patients: Results of a retrospective study.

Cayssials, Emilie; Torregrosa-Diaz, Jose; Gallego-Hernanz, Pilar; Tartarin, Florence; Systchenko, Thomas; Maillard, Natacha; Desmier, Déborah; Machet, Antoine; Fleck, Emmanuel; Corby, Anne; Motard, Carine; Denis, Guillaume; Herbelin, André; Gombert, Jean-Marc; Roy, Lydia; Ragot, Stéphanie; Leleu, Xavier; Guilhot, François; Chomel, Jean-Claude.

Cancer; 126(15): 3438-3447, 2020 Aug 01.

Artigo em Inglês | MEDLINE | ID: mdl-32459375

3.

Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia.

Hochhaus, Andreas; Larson, Richard A; Guilhot, François; Radich, Jerald P; Branford, Susan; Hughes, Timothy P; Baccarani, Michele; Deininger, Michael W; Cervantes, Francisco; Fujihara, Satoko; Ortmann, Christine-Elke; Menssen, Hans D; Kantarjian, Hagop; O'Brien, Stephen G; Druker, Brian J.

N Engl J Med; 376(10): 917-927, 2017 03 09.

Artigo em Inglês | MEDLINE | ID: mdl-28273028

4.

Ponatinib efficacy and safety in Philadelphia chromosome-positive leukemia: final 5-year results of the phase 2 PACE trial.

Cortes, Jorge E; Kim, Dong-Wook; Pinilla-Ibarz, Javier; le Coutre, Philipp D; Paquette, Ronald; Chuah, Charles; Nicolini, Franck E; Apperley, Jane F; Khoury, H Jean; Talpaz, Moshe; DeAngelo, Daniel J; Abruzzese, Elisabetta; Rea, Delphine; Baccarani, Michele; Müller, Martin C; Gambacorti-Passerini, Carlo; Lustgarten, Stephanie; Rivera, Victor M; Haluska, Frank G; Guilhot, François; Deininger, Michael W; Hochhaus, Andreas; Hughes, Timothy P; Shah, Neil P; Kantarjian, Hagop M.

Blood; 132(4): 393-404, 2018 07 26.

Artigo em Inglês | MEDLINE | ID: mdl-29567798

5.

Evaluation of Residual Disease and TKI Duration Are Critical Predictive Factors for Molecular Recurrence after Stopping Imatinib First-line in Chronic Phase CML Patients.

Nicolini, Franck Emmanuel; Dulucq, Stéphanie; Boureau, Lisa; Cony-Makhoul, Pascale; Charbonnier, Aude; Escoffre-Barbe, Martine; Rigal-Huguet, Françoise; Coiteux, Valérie; Varet, Bruno; Dubruille, Viviane; Lenain, Pascal; Rousselot, Philippe; Rea, Delphine; Guerci-Bresler, Agnès; Legros, Laurence; Liu, Jixing; Gardembas, Martine; Ianotto, Jean-Christophe; Turlure, Pascal; Johnson-Ansah, Hyacinthe; Martiniuc, Juliana; Jardel, Henry; Joly, Bertrand; Zunic, Patricia; Henni, Tawfiq; Villemagne, Bruno; Berger, Marc G; Cayssials, Emilie; Guilhot, François; Larosa, Fabrice; Guilhot, Joëlle; Etienne, Gabriel; Mahon, François-Xavier.

Clin Cancer Res; 25(22): 6606-6613, 2019 11 15.

Artigo em Inglês | MEDLINE | ID: mdl-31292142

6.

Sustained treatment-free remission in chronic myeloid leukaemia is associated with an increased frequency of innate CD8(+) T-cells.

Cayssials, Emilie; Jacomet, Florence; Piccirilli, Nathalie; Lefèvre, Lucie; Roy, Lydia; Guilhot, François; Chomel, Jean-Claude; Leleu, Xavier; Gombert, Jean-Marc; Herbelin, André; Barbarin, Alice.

Br J Haematol; 186(1): 54-59, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-30864168

7.

Discontinuation of dasatinib or nilotinib in chronic myeloid leukemia: interim analysis of the STOP 2G-TKI study.

Rea, Delphine; Nicolini, Franck E; Tulliez, Michel; Guilhot, François; Guilhot, Joelle; Guerci-Bresler, Agnès; Gardembas, Martine; Coiteux, Valérie; Guillerm, Gaelle; Legros, Laurence; Etienne, Gabriel; Pignon, Jean-Michel; Villemagne, Bruno; Escoffre-Barbe, Martine; Ianotto, Jean-Christophe; Charbonnier, Aude; Johnson-Ansah, Hyacinthe; Noel, Marie-Pierre; Rousselot, Philippe; Mahon, François-Xavier.

Blood; 129(7): 846-854, 2017 02 16.

Artigo em Inglês | MEDLINE | ID: mdl-27932374

8.

High-dose therapy and autologous stem cell transplantation in marginal zone lymphomas: a retrospective study by the EBMT Lymphoma Working Party and FIL-GITMO.

Avivi, Irit; Arcaini, Luca; Ferretti, Virginia V; Boumendil, Ariane; Finel, Hervé; Milone, Giuseppe; Zaja, Francesco; Liliana, Devizzi; Musso, Maurizio; Didier, Blaise; Bachy, Emmanuel; Wattad, Mohammed; Nicolas-Virelizier, Emmanuelle; Gramatzki, Martin; Bourhis, Jean-Henri; Caillot, Denis; Haenel, Anette; Held, Gerhard; Thieblemont, Catherine; Jindra, Pavel; Pohlreich, David; Guilhot, François; Kroschinsky, Frank; Wahlin, Björn; Scheid, Christof; Ifrah, Norbert; Berthou, Christian; Dreger, Peter; Montoto, Silvia; Conconi, Annarita.

Br J Haematol; 182(6): 807-815, 2018 09.

Artigo em Inglês | MEDLINE | ID: mdl-29984825

9.

Superoxide dismutase 2 (SOD2) contributes to genetic stability of native and T315I-mutated BCR-ABL expressing leukemic cells.

Girerd, Sandrine; Tosca, Lucie; Herault, Olivier; Vignon, Christine; Biard, Denis; Aggoune, Djamel; Dkhissi, Fatima; Bonnet, Marie Laure; Sorel, Nathalie; Desterke, Christophe; Bennaceur-Griscelli, Annelise; Tachdjian, Gerard; Guilhot, François; Guilhot, Joelle; Chomel, Jean-Claude; Turhan, Ali G.

Biochem Biophys Res Commun; 498(4): 715-722, 2018 04 15.

Artigo em Inglês | MEDLINE | ID: mdl-29550484

10.

Compound mutations in BCR-ABL1 are not major drivers of primary or secondary resistance to ponatinib in CP-CML patients.

Deininger, Michael W; Hodgson, J Graeme; Shah, Neil P; Cortes, Jorge E; Kim, Dong-Wook; Nicolini, Franck E; Talpaz, Moshe; Baccarani, Michele; Müller, Martin C; Li, Jin; Parker, Wendy T; Lustgarten, Stephanie; Clackson, Tim; Haluska, Frank G; Guilhot, Francois; Kantarjian, Hagop M; Soverini, Simona; Hochhaus, Andreas; Hughes, Timothy P; Rivera, Victor M; Branford, Susan.

Blood; 127(6): 703-12, 2016 Feb 11.

Artigo em Inglês | MEDLINE | ID: mdl-26603839

11.

Age-related health care disparities in multiple myeloma.

Puyade, Mathieu; Defossez, Gautier; Guilhot, François; Leleu, Xavier; Ingrand, Pierre.

Hematol Oncol; 36(1): 224-231, 2018 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-28429426

12.

Additional cytogenetic abnormalities and variant t(9;22) at the diagnosis of childhood chronic myeloid leukemia: The experience of the International Registry for Chronic Myeloid Leukemia in Children and Adolescents.

Millot, Frédéric; Dupraz, Christelle; Guilhot, Joelle; Suttorp, Meinolf; Brizard, Françoise; Leblanc, Thierry; Günes, Adalet Meral; Sedlacek, Petr; De Bont, Evelyne; Li, Chi Kong; Kalwak, Krzysztof; Lausen, Birgitte; Culic, Srdjana; Dworzak, Michael; Kaiserova, Emilia; De Moerloose, Barbara; Roula, Farah; Biondi, Andrea; Baruchel, André; Guilhot, François.

Cancer; 123(18): 3609-3616, 2017 Sep 15.

Artigo em Inglês | MEDLINE | ID: mdl-28497898

13.

Pioglitazone together with imatinib in chronic myeloid leukemia: A proof of concept study.

Rousselot, Philippe; Prost, Stéphane; Guilhot, Joelle; Roy, Lydia; Etienne, Gabriel; Legros, Laurence; Charbonnier, Aude; Coiteux, Valérie; Cony-Makhoul, Pascale; Huguet, Francoise; Cayssials, Emilie; Cayuela, Jean-Michel; Relouzat, Francis; Delord, Marc; Bruzzoni-Giovanelli, Heriberto; Morisset, Laure; Mahon, François-Xavier; Guilhot, François; Leboulch, Philippe.

Cancer; 123(10): 1791-1799, 2017 05 15.

Artigo em Inglês | MEDLINE | ID: mdl-28026860

14.

Natural killer-cell counts are associated with molecular relapse-free survival after imatinib discontinuation in chronic myeloid leukemia: the IMMUNOSTIM study.

Rea, Delphine; Henry, Guylaine; Khaznadar, Zena; Etienne, Gabriel; Guilhot, François; Nicolini, Franck; Guilhot, Joelle; Rousselot, Philippe; Huguet, Françoise; Legros, Laurence; Gardembas, Martine; Dubruille, Viviane; Guerci-Bresler, Agnès; Charbonnier, Aude; Maloisel, Frédéric; Ianotto, Jean-Christophe; Villemagne, Bruno; Mahon, François-Xavier; Moins-Teisserenc, Hélène; Dulphy, Nicolas; Toubert, Antoine.

Haematologica; 102(8): 1368-1377, 2017 08.

Artigo em Inglês | MEDLINE | ID: mdl-28522576

15.

The Rho-ROCK pathway as a new pathological mechanism of innate immune subversion in chronic myeloid leukaemia.

Basbous, Sara; Levescot, Anaïs; Piccirilli, Nathalie; Brizard, Françoise; Guilhot, François; Roy, Lydia; Bourmeyster, Nicolas; Gombert, Jean-Marc; Herbelin, André.

J Pathol; 240(3): 262-268, 2016 11.

Artigo em Inglês | MEDLINE | ID: mdl-27513300

16.

Physicians' attitude towards selection of second line therapy with nilotinib and dasatinib in chronic myeloid leukemia patients.

Breccia, Massimo; Baccarani, Michele; Rosti, Gianantonio; Cottone, Francesco; Cannella, Laura; Guilhot, François; Vignetti, Marco; Efficace, Fabio.

Health Qual Life Outcomes; 15(1): 204, 2017 Oct 18.

Artigo em Inglês | MEDLINE | ID: mdl-29047379

17.

Ponatinib versus imatinib for newly diagnosed chronic myeloid leukaemia: an international, randomised, open-label, phase 3 trial.

Lipton, Jeffrey H; Chuah, Charles; Guerci-Bresler, Agnès; Rosti, Gianantonio; Simpson, David; Assouline, Sarit; Etienne, Gabriel; Nicolini, Franck E; le Coutre, Philipp; Clark, Richard E; Stenke, Leif; Andorsky, David; Oehler, Vivian; Lustgarten, Stephanie; Rivera, Victor M; Clackson, Timothy; Haluska, Frank G; Baccarani, Michele; Cortes, Jorge E; Guilhot, François; Hochhaus, Andreas; Hughes, Timothy; Kantarjian, Hagop M; Shah, Neil P; Talpaz, Moshe; Deininger, Michael W.

Lancet Oncol; 17(5): 612-21, 2016 05.

Artigo em Inglês | MEDLINE | ID: mdl-27083332

18.

Evidence for eomesodermin-expressing innate-like CD8(+) KIR/NKG2A(+) T cells in human adults and cord blood samples.

Jacomet, Florence; Cayssials, Emilie; Basbous, Sara; Levescot, Anaïs; Piccirilli, Nathalie; Desmier, Deborah; Robin, Aurélie; Barra, Anne; Giraud, Christine; Guilhot, François; Roy, Lydia; Herbelin, André; Gombert, Jean-Marc.

Eur J Immunol; 45(7): 1926-33, 2015 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-25903796

19.

Ponatinib and platelets a conflict in CML.

Guilhot, François.

Blood; 133(14): 1520-1521, 2019 04 04.

Artigo em Inglês | MEDLINE | ID: mdl-30948369

20.

Long-term outcome with dasatinib after imatinib failure in chronic-phase chronic myeloid leukemia: follow-up of a phase 3 study.

Shah, Neil P; Guilhot, François; Cortes, Jorge E; Schiffer, Charles A; le Coutre, Philipp; Brümmendorf, Tim H; Kantarjian, Hagop M; Hochhaus, Andreas; Rousselot, Philippe; Mohamed, Hesham; Healey, Diane; Cunningham, Michael; Saglio, Giuseppe.

Blood; 123(15): 2317-24, 2014 Apr 10.

Artigo em Inglês | MEDLINE | ID: mdl-24569263

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