Pesquisa | Biblioteca Virtual em Saúde

1.

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma.

Varela, Ignacio; Tarpey, Patrick; Raine, Keiran; Huang, Dachuan; Ong, Choon Kiat; Stephens, Philip; Davies, Helen; Jones, David; Lin, Meng-Lay; Teague, Jon; Bignell, Graham; Butler, Adam; Cho, Juok; Dalgliesh, Gillian L; Galappaththige, Danushka; Greenman, Chris; Hardy, Claire; Jia, Mingming; Latimer, Calli; Lau, King Wai; Marshall, John; McLaren, Stuart; Menzies, Andrew; Mudie, Laura; Stebbings, Lucy; Largaespada, David A; Wessels, L F A; Richard, Stephane; Kahnoski, Richard J; Anema, John; Tuveson, David A; Perez-Mancera, Pedro A; Mustonen, Ville; Fischer, Andrej; Adams, David J; Rust, Alistair; Chan-on, Waraporn; Subimerb, Chutima; Dykema, Karl; Furge, Kyle; Campbell, Peter J; Teh, Bin Tean; Stratton, Michael R; Futreal, P Andrew.

Nature; 469(7331): 539-42, 2011 Jan 27.

Artigo em Inglês | MEDLINE | ID: mdl-21248752

2.

The value of monitoring to control evolving populations.

Fischer, Andrej; Vázquez-García, Ignacio; Mustonen, Ville.

Proc Natl Acad Sci U S A; 112(4): 1007-12, 2015 Jan 27.

Artigo em Inglês | MEDLINE | ID: mdl-25587136

3.

Adenoma development in familial adenomatous polyposis and MUTYH-associated polyposis: somatic landscape and driver genes.

Rashid, Mamunur; Fischer, Andrej; Wilson, Cathy H; Tiffen, Jessamy; Rust, Alistair G; Stevens, Philip; Idziaszczyk, Shelley; Maynard, Julie; Williams, Geraint T; Mustonen, Ville; Sampson, Julian R; Adams, David J.

J Pathol; 238(1): 98-108, 2016 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-26414517

4.

Identifying selection in the within-host evolution of influenza using viral sequence data.

Illingworth, Christopher J R; Fischer, Andrej; Mustonen, Ville.

PLoS Comput Biol; 10(7): e1003755, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-25080215

5.

Rare events in population genetics: stochastic tunneling in a two-locus model with recombination.

Altland, Alexander; Fischer, Andrej; Krug, Joachim; Szendro, Ivan G.

Phys Rev Lett; 106(8): 088101, 2011 Feb 25.

Artigo em Inglês | MEDLINE | ID: mdl-21405603

6.

Clonal Heterogeneity Influences the Fate of New Adaptive Mutations.

Vázquez-García, Ignacio; Salinas, Francisco; Li, Jing; Fischer, Andrej; Barré, Benjamin; Hallin, Johan; Bergström, Anders; Alonso-Perez, Elisa; Warringer, Jonas; Mustonen, Ville; Liti, Gianni.

Cell Rep; 21(3): 732-744, 2017 Oct 17.

Artigo em Inglês | MEDLINE | ID: mdl-29045840

7.

High-definition reconstruction of clonal composition in cancer.

Fischer, Andrej; Vázquez-García, Ignacio; Illingworth, Christopher J R; Mustonen, Ville.

Cell Rep; 7(5): 1740-1752, 2014 Jun 12.

Artigo em Inglês | MEDLINE | ID: mdl-24882004

8.

EMu: probabilistic inference of mutational processes and their localization in the cancer genome.

Fischer, Andrej; Illingworth, Christopher J R; Campbell, Peter J; Mustonen, Ville.

Genome Biol; 14(4): R39, 2013 Apr 29.

Artigo em Inglês | MEDLINE | ID: mdl-23628380

9.

Germline fitness-based scoring of cancer mutations.

Fischer, Andrej; Greenman, Chris; Mustonen, Ville.

Genetics; 188(2): 383-93, 2011 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-21441214

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