Pesquisa | Biblioteca Virtual em Saúde

1.

FXR Regulates Intestinal Cancer Stem Cell Proliferation.

Fu, Ting; Coulter, Sally; Yoshihara, Eiji; Oh, Tae Gyu; Fang, Sungsoon; Cayabyab, Fritz; Zhu, Qiyun; Zhang, Tong; Leblanc, Mathias; Liu, Sihao; He, Mingxiao; Waizenegger, Wanda; Gasser, Emanuel; Schnabl, Bernd; Atkins, Annette R; Yu, Ruth T; Knight, Rob; Liddle, Christopher; Downes, Michael; Evans, Ronald M.

Cell; 176(5): 1098-1112.e18, 2019 02 21.

Artigo em Inglês | MEDLINE | ID: mdl-30794774

2.

Vitamin D Switches BAF Complexes to Protect ß Cells.

Wei, Zong; Yoshihara, Eiji; He, Nanhai; Hah, Nasun; Fan, Weiwei; Pinto, Antonio F M; Huddy, Timothy; Wang, Yuhao; Ross, Brittany; Estepa, Gabriela; Dai, Yang; Ding, Ning; Sherman, Mara H; Fang, Sungsoon; Zhao, Xuan; Liddle, Christopher; Atkins, Annette R; Yu, Ruth T; Downes, Michael; Evans, Ronald M.

Cell; 173(5): 1135-1149.e15, 2018 May 17.

Artigo em Inglês | MEDLINE | ID: mdl-29754817

3.

Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation.

Zhao, Xuan; Hirota, Tsuyoshi; Han, Xuemei; Cho, Han; Chong, Ling-Wa; Lamia, Katja; Liu, Sihao; Atkins, Annette R; Banayo, Ester; Liddle, Christopher; Yu, Ruth T; Yates, John R; Kay, Steve A; Downes, Michael; Evans, Ronald M.

Cell; 165(7): 1644-1657, 2016 Jun 16.

Artigo em Inglês | MEDLINE | ID: mdl-27238018

4.

Turning up the heat on membrane fluidity.

Fan, Weiwei; Evans, Ronald M.

Cell; 161(5): 962-963, 2015 May 21.

Artigo em Inglês | MEDLINE | ID: mdl-26000475

5.

Nuclear Receptors, RXR, and the Big Bang.

Evans, Ronald M; Mangelsdorf, David J.

Cell; 157(1): 255-66, 2014 Mar 27.

Artigo em Inglês | MEDLINE | ID: mdl-24679540

6.

Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.

Sherman, Mara H; Yu, Ruth T; Engle, Dannielle D; Ding, Ning; Atkins, Annette R; Tiriac, Herve; Collisson, Eric A; Connor, Frances; Van Dyke, Terry; Kozlov, Serguei; Martin, Philip; Tseng, Tiffany W; Dawson, David W; Donahue, Timothy R; Masamune, Atsushi; Shimosegawa, Tooru; Apte, Minoti V; Wilson, Jeremy S; Ng, Beverly; Lau, Sue Lynn; Gunton, Jenny E; Wahl, Geoffrey M; Hunter, Tony; Drebin, Jeffrey A; O'Dwyer, Peter J; Liddle, Christopher; Tuveson, David A; Downes, Michael; Evans, Ronald M.

Cell; 159(1): 80-93, 2014 Sep 25.

Artigo em Inglês | MEDLINE | ID: mdl-25259922

7.

SRF'ing around the clock.

Zhao, Xuan; Cho, Han; Evans, Ronald M.

Cell; 152(3): 381-2, 2013 Jan 31.

Artigo em Inglês | MEDLINE | ID: mdl-23374332

8.

A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response.

Ding, Ning; Yu, Ruth T; Subramaniam, Nanthakumar; Sherman, Mara H; Wilson, Caroline; Rao, Renuka; Leblanc, Mathias; Coulter, Sally; He, Mingxiao; Scott, Christopher; Lau, Sue L; Atkins, Annette R; Barish, Grant D; Gunton, Jenny E; Liddle, Christopher; Downes, Michael; Evans, Ronald M.

Cell; 153(3): 601-13, 2013 Apr 25.

Artigo em Inglês | MEDLINE | ID: mdl-23622244

9.

Barx2 and Pax7 Regulate Axin2 Expression in Myoblasts by Interaction with ß-Catenin and Chromatin Remodelling.

Hulin, Julie-Ann; Nguyen, Thi Diem Tran; Cui, Shuang; Marri, Shashikanth; Yu, Ruth T; Downes, Michael; Evans, Ronald M; Makarenkova, Helen; Meech, Robyn.

Stem Cells; 34(8): 2169-82, 2016 08.

Artigo em Inglês | MEDLINE | ID: mdl-27144473

10.

Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis.

Mihaylova, Maria M; Vasquez, Debbie S; Ravnskjaer, Kim; Denechaud, Pierre-Damien; Yu, Ruth T; Alvarez, Jacqueline G; Downes, Michael; Evans, Ronald M; Montminy, Marc; Shaw, Reuben J.

Cell; 145(4): 607-21, 2011 May 13.

Artigo em Inglês | MEDLINE | ID: mdl-21565617

11.

NCoR1 is a conserved physiological modulator of muscle mass and oxidative function.

Yamamoto, Hiroyasu; Williams, Evan G; Mouchiroud, Laurent; Cantó, Carles; Fan, Weiwei; Downes, Michael; Héligon, Christophe; Barish, Grant D; Desvergne, Béatrice; Evans, Ronald M; Schoonjans, Kristina; Auwerx, Johan.

Cell; 147(4): 827-39, 2011 Nov 11.

Artigo em Inglês | MEDLINE | ID: mdl-22078881

12.

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.

Shi, Yu; Gao, Weina; Lytle, Nikki K; Huang, Peiwu; Yuan, Xiao; Dann, Amanda M; Ridinger-Saison, Maya; DelGiorno, Kathleen E; Antal, Corina E; Liang, Gaoyang; Atkins, Annette R; Erikson, Galina; Sun, Huaiyu; Meisenhelder, Jill; Terenziani, Elena; Woo, Gyunghwi; Fang, Linjing; Santisakultarm, Thom P; Manor, Uri; Xu, Ruilian; Becerra, Carlos R; Borazanci, Erkut; Von Hoff, Daniel D; Grandgenett, Paul M; Hollingsworth, Michael A; Leblanc, Mathias; Umetsu, Sarah E; Collisson, Eric A; Scadeng, Miriam; Lowy, Andrew M; Donahue, Timothy R; Reya, Tannishtha; Downes, Michael; Evans, Ronald M; Wahl, Geoffrey M; Pawson, Tony; Tian, Ruijun; Hunter, Tony.

Nature; 569(7754): 131-135, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-30996350

13.

Author Correction: Inflammation-induced IgA⁺ cells dismantle anti-liver cancer immunity.

Shalapour, Shabnam; Lin, Xue-Jia; Bastian, Ingmar N; Brain, John; Burt, Alastair D; Aksenov, Alexander A; Vrbanac, Alison F; Li, Weihua; Perkins, Andres; Matsutani, Takaji; Zhong, Zhenyu; Dhar, Debanjan; Navas-Molina, Jose A; Xu, Jun; Loomba, Rohit; Downes, Michael; Yu, Ruth T; Evans, Ronald M; Dorrestein, Pieter C; Knight, Rob; Benner, Christopher; Anstee, Quentin M; Karin, Michael.

Nature; 561(7721): E1, 2018 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-29973714

14.

AMPK and PPARdelta agonists are exercise mimetics.

Narkar, Vihang A; Downes, Michael; Yu, Ruth T; Embler, Emi; Wang, Yong-Xu; Banayo, Ester; Mihaylova, Maria M; Nelson, Michael C; Zou, Yuhua; Juguilon, Henry; Kang, Heonjoong; Shaw, Reuben J; Evans, Ronald M.

Cell; 134(3): 405-15, 2008 Aug 08.

Artigo em Inglês | MEDLINE | ID: mdl-18674809

15.

Erratum: Inflammation-induced IgA⁺ cells dismantle anti-liver cancer immunity.

Shalapour, Shabnam; Lin, Xue-Jia; Bastian, Ingmar N; Brain, John; Burt, Alastair D; Aksenov, Alexander A; Vrbanac, Alison F; Li, Weihua; Perkins, Andres; Matsutani, Takaji; Zhong, Zhenyu; Dhar, Debanjan; Navas-Molina, Jose A; Xu, Jun; Loomba, Rohit; Downes, Michael; Yu, Ruth T; Evans, Ronald M; Dorrestein, Pieter C; Knight, Rob; Benner, Christopher; Anstee, Quentin M; Karin, Michael.

Nature; 552(7685): 430, 2017 12 21.

Artigo em Inglês | MEDLINE | ID: mdl-29168501

16.

Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity.

Shalapour, Shabnam; Lin, Xue-Jia; Bastian, Ingmar N; Brain, John; Burt, Alastair D; Aksenov, Alexander A; Vrbanac, Alison F; Li, Weihua; Perkins, Andres; Matsutani, Takaji; Zhong, Zhenyu; Dhar, Debanjan; Navas-Molina, Jose A; Xu, Jun; Loomba, Rohit; Downes, Michael; Yu, Ruth T; Evans, Ronald M; Dorrestein, Pieter C; Knight, Rob; Benner, Christopher; Anstee, Quentin M; Karin, Michael.

Nature; 551(7680): 340-345, 2017 11 16.

Artigo em Inglês | MEDLINE | ID: mdl-29144460

17.

ß-Catenin is essential for differentiation of primary myoblasts via cooperation with MyoD and α-catenin.

Cui, Shuang; Li, Liang; Yu, Ruth T; Downes, Michael; Evans, Ronald M; Hulin, Julie-Ann; Makarenkova, Helen P; Meech, Robyn.

Development; 146(6)2019 Mar 19.

Artigo em Inglês | MEDLINE | ID: mdl-30683662

18.

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

Sousa, Cristovão M; Biancur, Douglas E; Wang, Xiaoxu; Halbrook, Christopher J; Sherman, Mara H; Zhang, Li; Kremer, Daniel; Hwang, Rosa F; Witkiewicz, Agnes K; Ying, Haoqiang; Asara, John M; Evans, Ronald M; Cantley, Lewis C; Lyssiotis, Costas A; Kimmelman, Alec C.

Nature; 536(7617): 479-83, 2016 08 25.

Artigo em Inglês | MEDLINE | ID: mdl-27509858

19.

The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease.

Chang, Christina; Loo, Chin-San; Zhao, Xuan; Solt, Laura A; Liang, Yuqiong; Bapat, Sagar P; Cho, Han; Kamenecka, Theodore M; Leblanc, Mathias; Atkins, Annette R; Yu, Ruth T; Downes, Michael; Burris, Thomas P; Evans, Ronald M; Zheng, Ye.

Proc Natl Acad Sci U S A; 116(37): 18528-18536, 2019 Sep 10.

Artigo em Inglês | MEDLINE | ID: mdl-31455731

20.

YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity.

Wang, Lirui; Mazagova, Magdalena; Pan, Chuyue; Yang, Song; Brandl, Katharina; Liu, Jun; Reilly, Shannon M; Wang, Yanhan; Miao, Zhaorui; Loomba, Rohit; Lu, Na; Guo, Qinglong; Liu, Jihua; Yu, Ruth T; Downes, Michael; Evans, Ronald M; Brenner, David A; Saltiel, Alan R; Beutler, Bruce; Schnabl, Bernd.

Proc Natl Acad Sci U S A; 116(30): 15184-15193, 2019 Jul 23.

Artigo em Inglês | MEDLINE | ID: mdl-31289229

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FXR Regulates Intestinal Cancer Stem Cell Proliferation.

Vitamin D Switches BAF Complexes to Protect ß Cells.

Circadian Amplitude Regulation via FBXW7-Targeted REV-ERBα Degradation.

Turning up the heat on membrane fluidity.

Nuclear Receptors, RXR, and the Big Bang.

Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy.

SRF'ing around the clock.

A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic response.

Barx2 and Pax7 Regulate Axin2 Expression in Myoblasts by Interaction with ß-Catenin and Chromatin Remodelling.

Class IIa histone deacetylases are hormone-activated regulators of FOXO and mammalian glucose homeostasis.

NCoR1 is a conserved physiological modulator of muscle mass and oxidative function.

Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring.

Author Correction: Inflammation-induced IgA⁺ cells dismantle anti-liver cancer immunity.

AMPK and PPARdelta agonists are exercise mimetics.

Erratum: Inflammation-induced IgA⁺ cells dismantle anti-liver cancer immunity.

Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity.

ß-Catenin is essential for differentiation of primary myoblasts via cooperation with MyoD and α-catenin.

Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion.

The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease.

YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity.