Pesquisa | Biblioteca Virtual em Saúde

1.

Self-Reactive B Cells in the Germinal Center Reaction.

Brink, Robert; Phan, Tri Giang.

Annu Rev Immunol; 36: 339-357, 2018 04 26.

Artigo em Inglês | MEDLINE | ID: mdl-29356584

2.

Lymphoma Driver Mutations in the Pathogenic Evolution of an Iconic Human Autoantibody.

Singh, Mandeep; Jackson, Katherine J L; Wang, Jing J; Schofield, Peter; Field, Matt A; Koppstein, David; Peters, Timothy J; Burnett, Deborah L; Rizzetto, Simone; Nevoltris, Damien; Masle-Farquhar, Etienne; Faulks, Megan L; Russell, Amanda; Gokal, Divya; Hanioka, Asami; Horikawa, Keisuke; Colella, Alexander D; Chataway, Timothy K; Blackburn, James; Mercer, Tim R; Langley, David B; Goodall, D Margaret; Jefferis, Roy; Gangadharan Komala, Muralikrishna; Kelleher, Anthony D; Suan, Dan; Rischmueller, Maureen; Christ, Daniel; Brink, Robert; Luciani, Fabio; Gordon, Tom P; Goodnow, Christopher C; Reed, Joanne H.

Cell; 180(5): 878-894.e19, 2020 03 05.

Artigo em Inglês | MEDLINE | ID: mdl-32059783

3.

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production.

Randall, Katrina L; Lambe, Teresa; Johnson, Andy L; Johnson, Andy; Treanor, Bebhinn; Kucharska, Edyta; Domaschenz, Heather; Whittle, Belinda; Tze, Lina E; Enders, Anselm; Crockford, Tanya L; Bouriez-Jones, Tiphaine; Alston, Duncan; Cyster, Jason G; Lenardo, Michael J; Mackay, Fabienne; Deenick, Elissa K; Tangye, Stuart G; Chan, Tyani D; Camidge, Tahra; Brink, Robert; Vinuesa, Carola G; Batista, Facundo D; Cornall, Richard J; Goodnow, Christopher C.

Nat Immunol; 10(12): 1283-91, 2009 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-19898472

4.

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity.

Zammit, Nathan W; Siggs, Owen M; Gray, Paul E; Horikawa, Keisuke; Langley, David B; Walters, Stacey N; Daley, Stephen R; Loetsch, Claudia; Warren, Joanna; Yap, Jin Yan; Cultrone, Daniele; Russell, Amanda; Malle, Elisabeth K; Villanueva, Jeanette E; Cowley, Mark J; Gayevskiy, Velimir; Dinger, Marcel E; Brink, Robert; Zahra, David; Chaudhri, Geeta; Karupiah, Gunasegaran; Whittle, Belinda; Roots, Carla; Bertram, Edward; Yamada, Michiko; Jeelall, Yogesh; Enders, Anselm; Clifton, Benjamin E; Mabbitt, Peter D; Jackson, Colin J; Watson, Susan R; Jenne, Craig N; Lanier, Lewis L; Wiltshire, Tim; Spitzer, Matthew H; Nolan, Garry P; Schmitz, Frank; Aderem, Alan; Porebski, Benjamin T; Buckle, Ashley M; Abbott, Derek W; Ziegler, John B; Craig, Maria E; Benitez-Aguirre, Paul; Teo, Juliana; Tangye, Stuart G; King, Cecile; Wong, Melanie; Cox, Murray P; Phung, Wilson.

Nat Immunol; 20(10): 1299-1310, 2019 10.

Artigo em Inglês | MEDLINE | ID: mdl-31534238

5.

SnapShot: Interactions between B Cells and T Cells.

Tangye, Stuart G; Brink, Robert; Goodnow, Christopher C; Phan, Tri Giang.

Cell; 162(4): 926-6.e1, 2015 Aug 13.

Artigo em Inglês | MEDLINE | ID: mdl-26276638

6.

Follicular dendritic cells emerge from ubiquitous perivascular precursors.

Krautler, Nike Julia; Kana, Veronika; Kranich, Jan; Tian, Yinghua; Perera, Dushan; Lemm, Doreen; Schwarz, Petra; Armulik, Annika; Browning, Jeffrey L; Tallquist, Michelle; Buch, Thorsten; Oliveira-Martins, José B; Zhu, Caihong; Hermann, Mario; Wagner, Ulrich; Brink, Robert; Heikenwalder, Mathias; Aguzzi, Adriano.

Cell; 150(1): 194-206, 2012 Jul 06.

Artigo em Inglês | MEDLINE | ID: mdl-22770220

7.

CCR6 Defines Memory B Cell Precursors in Mouse and Human Germinal Centers, Revealing Light-Zone Location and Predominant Low Antigen Affinity.

Suan, Dan; Kräutler, Nike J; Maag, Jesper L V; Butt, Danyal; Bourne, Katherine; Hermes, Jana R; Avery, Danielle T; Young, Clara; Statham, Aaron; Elliott, Michael; Dinger, Marcel E; Basten, Antony; Tangye, Stuart G; Brink, Robert.

Immunity; 47(6): 1142-1153.e4, 2017 12 19.

Artigo em Inglês | MEDLINE | ID: mdl-29262350

8.

The chemotactic receptor EBI2 regulates the homeostasis, localization and immunological function of splenic dendritic cells.

Gatto, Dominique; Wood, Katherine; Caminschi, Irina; Murphy-Durland, Danielle; Schofield, Peter; Christ, Daniel; Karupiah, Gunasegaran; Brink, Robert.

Nat Immunol; 14(5): 446-53, 2013 May.

Artigo em Inglês | MEDLINE | ID: mdl-23502855

9.

FAS Inactivation Releases Unconventional Germinal Center B Cells that Escape Antigen Control and Drive IgE and Autoantibody Production.

Butt, Danyal; Chan, Tyani D; Bourne, Katherine; Hermes, Jana R; Nguyen, Akira; Statham, Aaron; O'Reilly, Lorraine A; Strasser, Andreas; Price, Susan; Schofield, Peter; Christ, Daniel; Basten, Antony; Ma, Cindy S; Tangye, Stuart G; Phan, Tri Giang; Rao, V Koneti; Brink, Robert.

Immunity; 42(5): 890-902, 2015 May 19.

Artigo em Inglês | MEDLINE | ID: mdl-25979420

10.

T follicular helper cells have distinct modes of migration and molecular signatures in naive and memory immune responses.

Suan, Dan; Nguyen, Akira; Moran, Imogen; Bourne, Katherine; Hermes, Jana R; Arshi, Mehreen; Hampton, Henry R; Tomura, Michio; Miwa, Yoshihiro; Kelleher, Anthony D; Kaplan, Warren; Deenick, Elissa K; Tangye, Stuart G; Brink, Robert; Chtanova, Tatyana; Phan, Tri Giang.

Immunity; 42(4): 704-18, 2015 Apr 21.

Artigo em Inglês | MEDLINE | ID: mdl-25840682

11.

Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses.

Chang, Pheh-Ping; Barral, Patricia; Fitch, Jessica; Pratama, Alvin; Ma, Cindy S; Kallies, Axel; Hogan, Jennifer J; Cerundolo, Vincenzo; Tangye, Stuart G; Bittman, Robert; Nutt, Stephen L; Brink, Robert; Godfrey, Dale I; Batista, Facundo D; Vinuesa, Carola G.

Nat Immunol; 13(1): 35-43, 2011 Nov 27.

Artigo em Inglês | MEDLINE | ID: mdl-22120117

12.

LOX-1 unlocks human plasma cell potential.

Brink, Robert.

Immunity; 41(4): 507-8, 2014 Oct 16.

Artigo em Inglês | MEDLINE | ID: mdl-25367564

13.

Control systems and decision making for antibody production.

Goodnow, Christopher C; Vinuesa, Carola G; Randall, Katrina L; Mackay, Fabienne; Brink, Robert.

Nat Immunol; 11(8): 681-8, 2010 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-20644574

14.

Transcriptional regulation of germinal center B and plasma cell fates by dynamical control of IRF4.

Ochiai, Kyoko; Maienschein-Cline, Mark; Simonetti, Giorgia; Chen, Jianjun; Rosenthal, Rebecca; Brink, Robert; Chong, Anita S; Klein, Ulf; Dinner, Aaron R; Singh, Harinder; Sciammas, Roger.

Immunity; 38(5): 918-29, 2013 May 23.

Artigo em Inglês | MEDLINE | ID: mdl-23684984

15.

Circulating precursor CCR7(lo)PD-1(hi) CXCR5âº CD4âº T cells indicate Tfh cell activity and promote antibody responses upon antigen reexposure.

He, Jing; Tsai, Louis M; Leong, Yew Ann; Hu, Xin; Ma, Cindy S; Chevalier, Nina; Sun, Xiaolin; Vandenberg, Kirsten; Rockman, Steve; Ding, Yan; Zhu, Lei; Wei, Wei; Wang, Changqi; Karnowski, Alexander; Belz, Gabrielle T; Ghali, Joanna R; Cook, Matthew C; Riminton, D Sean; Veillette, André; Schwartzberg, Pamela L; Mackay, Fabienne; Brink, Robert; Tangye, Stuart G; Vinuesa, Carola G; Mackay, Charles R; Li, Zhanguo; Yu, Di.

Immunity; 39(4): 770-81, 2013 Oct 17.

Artigo em Inglês | MEDLINE | ID: mdl-24138884

16.

Aryl hydrocarbon receptor is required for optimal B-cell proliferation.

Villa, Matteo; Gialitakis, Manolis; Tolaini, Mauro; Ahlfors, Helena; Henderson, Colin J; Wolf, C Roland; Brink, Robert; Stockinger, Brigitta.

EMBO J; 36(1): 116-128, 2017 01 04.

Artigo em Inglês | MEDLINE | ID: mdl-27875245

17.

Elimination of germinal-center-derived self-reactive B cells is governed by the location and concentration of self-antigen.

Chan, Tyani D; Wood, Katherine; Hermes, Jana R; Butt, Danyal; Jolly, Christopher J; Basten, Antony; Brink, Robert.

Immunity; 37(5): 893-904, 2012 Nov 16.

Artigo em Inglês | MEDLINE | ID: mdl-23142780

18.

SAMHD1 enhances immunoglobulin hypermutation by promoting transversion mutation.

Thientosapol, Eddy Sanchai; Bosnjak, Daniel; Durack, Timothy; Stevanovski, Igor; van Geldermalsen, Michelle; Holst, Jeff; Jahan, Zeenat; Shepard, Caitlin; Weninger, Wolfgang; Kim, Baek; Brink, Robert; Jolly, Christopher J.

Proc Natl Acad Sci U S A; 115(19): 4921-4926, 2018 05 08.

Artigo em Inglês | MEDLINE | ID: mdl-29669924

19.

Germinal centers and autoantibodies.

Young, Clara; Brink, Robert.

Immunol Cell Biol; 98(6): 480-489, 2020 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-32080878

20.

In vivo photolabeling of tumor-infiltrating cells reveals highly regulated egress of T-cell subsets from tumors.

Torcellan, Tommaso; Hampton, Henry R; Bailey, Jacqueline; Tomura, Michio; Brink, Robert; Chtanova, Tatyana.

Proc Natl Acad Sci U S A; 114(22): 5677-5682, 2017 05 30.

Artigo em Inglês | MEDLINE | ID: mdl-28507145

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