Pesquisa | Biblioteca Virtual em Saúde

1.

Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence.

Harel, Michal; Ortenberg, Rona; Varanasi, Siva Karthik; Mangalhara, Kailash Chandra; Mardamshina, Mariya; Markovits, Ettai; Baruch, Erez N; Tripple, Victoria; Arama-Chayoth, May; Greenberg, Eyal; Shenoy, Anjana; Ayasun, Ruveyda; Knafo, Naama; Xu, Shihao; Anafi, Liat; Yanovich-Arad, Gali; Barnabas, Georgina D; Ashkenazi, Shira; Besser, Michal J; Schachter, Jacob; Bosenberg, Marcus; Shadel, Gerald S; Barshack, Iris; Kaech, Susan M; Markel, Gal; Geiger, Tamar.

Cell; 179(1): 236-250.e18, 2019 Sep 19.

Artigo em Inglês | MEDLINE | ID: mdl-31495571

2.

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

Ho, Ping-Chih; Bihuniak, Jessica Dauz; Macintyre, Andrew N; Staron, Matthew; Liu, Xiaojing; Amezquita, Robert; Tsui, Yao-Chen; Cui, Guoliang; Micevic, Goran; Perales, Jose C; Kleinstein, Steven H; Abel, E Dale; Insogna, Karl L; Feske, Stefan; Locasale, Jason W; Bosenberg, Marcus W; Rathmell, Jeffrey C; Kaech, Susan M.

Cell; 162(6): 1217-28, 2015 Sep 10.

Artigo em Inglês | MEDLINE | ID: mdl-26321681

3.

The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression.

Pan, Wen; Zhu, Shu; Qu, Kun; Meeth, Katrina; Cheng, Jijun; He, Kaixin; Ma, Hongdi; Liao, Yan; Wen, Xizhi; Roden, Christine; Tobiasova, Zuzana; Wei, Zheng; Zhao, Jun; Liu, Jun; Zheng, Ji; Guo, Bo; Khan, Sajid A; Bosenberg, Marcus; Flavell, Richard A; Lu, Jun.

Immunity; 47(2): 284-297.e5, 2017 08 15.

Artigo em Inglês | MEDLINE | ID: mdl-28813659

4.

Coordinated activation of Wnt in epithelial and melanocyte stem cells initiates pigmented hair regeneration.

Rabbani, Piul; Takeo, Makoto; Chou, WeiChin; Myung, Peggy; Bosenberg, Marcus; Chin, Lynda; Taketo, M Mark; Ito, Mayumi.

Cell; 145(6): 941-955, 2011 Jun 10.

Artigo em Inglês | MEDLINE | ID: mdl-21663796

5.

PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion.

Tinoco, Roberto; Carrette, Florent; Barraza, Monique L; Otero, Dennis C; Magaña, Jonathan; Bosenberg, Marcus W; Swain, Susan L; Bradley, Linda M.

Immunity; 44(5): 1190-203, 2016 05 17.

Artigo em Inglês | MEDLINE | ID: mdl-27192578

6.

Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.

Salmon, Hélène; Idoyaga, Juliana; Rahman, Adeeb; Leboeuf, Marylène; Remark, Romain; Jordan, Stefan; Casanova-Acebes, Maria; Khudoynazarova, Makhzuna; Agudo, Judith; Tung, Navpreet; Chakarov, Svetoslav; Rivera, Christina; Hogstad, Brandon; Bosenberg, Marcus; Hashimoto, Daigo; Gnjatic, Sacha; Bhardwaj, Nina; Palucka, Anna Karolina; Brown, Brian D; Brody, Joshua; Ginhoux, Florent; Merad, Miriam.

Immunity; 44(4): 924-38, 2016 Apr 19.

Artigo em Inglês | MEDLINE | ID: mdl-27096321

7.

Lineage-specific transcriptional regulation of DICER by MITF in melanocytes.

Levy, Carmit; Khaled, Mehdi; Robinson, Kathleen C; Veguilla, Rosa A; Chen, Po-Hao; Yokoyama, Satoru; Makino, Eiichi; Lu, Jun; Larue, Lionel; Beermann, Friedrich; Chin, Lynda; Bosenberg, Marcus; Song, Jun S; Fisher, David E.

Cell; 141(6): 994-1005, 2010 Jun 11.

Artigo em Inglês | MEDLINE | ID: mdl-20550935

8.

Autophagy maintains tumour growth through circulating arginine.

Poillet-Perez, Laura; Xie, Xiaoqi; Zhan, Le; Yang, Yang; Sharp, Daniel W; Hu, Zhixian Sherrie; Su, Xiaoyang; Maganti, Anurag; Jiang, Cherry; Lu, Wenyun; Zheng, Haiyan; Bosenberg, Marcus W; Mehnert, Janice M; Guo, Jessie Yanxiang; Lattime, Edmund; Rabinowitz, Joshua D; White, Eileen.

Nature; 563(7732): 569-573, 2018 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-30429607

9.

Author Correction: Autophagy maintains tumour growth through circulating arginine.

Poillet-Perez, Laura; Xie, Xiaoqi; Zhan, Le; Yang, Yang; Sharp, Daniel W; Hu, Zhixian Sherrie; Su, Xiaoyang; Maganti, Anurag; Jiang, Cherry; Lu, Wenyun; Zheng, Haiyan; Bosenberg, Marcus W; Mehnert, Janice M; Guo, Jessie Yanxiang; Lattime, Edmund; Rabinowitz, Joshua D; White, Eileen.

Nature; 2018 Dec 06.

Artigo em Inglês | MEDLINE | ID: mdl-30523330

10.

sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance.

Kaur, Amanpreet; Webster, Marie R; Marchbank, Katie; Behera, Reeti; Ndoye, Abibatou; Kugel, Curtis H; Dang, Vanessa M; Appleton, Jessica; O'Connell, Michael P; Cheng, Phil; Valiga, Alexander A; Morissette, Rachel; McDonnell, Nazli B; Ferrucci, Luigi; Kossenkov, Andrew V; Meeth, Katrina; Tang, Hsin-Yao; Yin, Xiangfan; Wood, William H; Lehrmann, Elin; Becker, Kevin G; Flaherty, Keith T; Frederick, Dennie T; Wargo, Jennifer A; Cooper, Zachary A; Tetzlaff, Michael T; Hudgens, Courtney; Aird, Katherine M; Zhang, Rugang; Xu, Xiaowei; Liu, Qin; Bartlett, Edmund; Karakousis, Giorgos; Eroglu, Zeynep; Lo, Roger S; Chan, Matthew; Menzies, Alexander M; Long, Georgina V; Johnson, Douglas B; Sosman, Jeffrey; Schilling, Bastian; Schadendorf, Dirk; Speicher, David W; Bosenberg, Marcus; Ribas, Antoni; Weeraratna, Ashani T.

Nature; 532(7598): 250-4, 2016 Apr 14.

Artigo em Inglês | MEDLINE | ID: mdl-27042933

11.

Therapy-induced tumour secretomes promote resistance and tumour progression.

Obenauf, Anna C; Zou, Yilong; Ji, Andrew L; Vanharanta, Sakari; Shu, Weiping; Shi, Hubing; Kong, Xiangju; Bosenberg, Marcus C; Wiesner, Thomas; Rosen, Neal; Lo, Roger S; Massagué, Joan.

Nature; 520(7547): 368-72, 2015 Apr 16.

Artigo em Inglês | MEDLINE | ID: mdl-25807485

12.

PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion.

Tinoco, Roberto; Carrette, Florent; Barraza, Monique L; Otero, Dennis C; Magaña, Jonathan; Bosenberg, Marcus W; Swain, Susan L; Bradley, Linda M.

Immunity; 44(6): 1470, 2016 Jun 21.

Artigo em Inglês | MEDLINE | ID: mdl-27332735

13.

scFTD-seq: freeze-thaw lysis based, portable approach toward highly distributed single-cell 3' mRNA profiling.

Dura, Burak; Choi, Jin-Young; Zhang, Kerou; Damsky, William; Thakral, Durga; Bosenberg, Marcus; Craft, Joe; Fan, Rong.

Nucleic Acids Res; 2018 Nov 20.

Artigo em Inglês | MEDLINE | ID: mdl-30462277

14.

Stem cell-released oncolytic herpes simplex virus has therapeutic efficacy in brain metastatic melanomas.

Du, Wanlu; Seah, Ivan; Bougazzoul, Oumaima; Choi, GiHun; Meeth, Katrina; Bosenberg, Marcus W; Wakimoto, Hiroaki; Fisher, David; Shah, Khalid.

Proc Natl Acad Sci U S A; 114(30): E6157-E6165, 2017 07 25.

Artigo em Inglês | MEDLINE | ID: mdl-28710334

15.

PLEKHA5 regulates tumor growth in metastatic melanoma.

Zhang, Hongyi; Zhu, Huifang; Deng, Gang; Zito, Christopher R; Oria, Victor O; Rane, Chetan K; Zhang, Shenqi; Weiss, Sarah A; Tran, Thuy; Adeniran, Adebowale; Zhang, Fanfan; Zhou, Jiangbing; Kluger, Yuval; Bosenberg, Marcus W; Kluger, Harriet M; Jilaveanu, Lucia B.

Cancer; 2019 Nov 26.

Artigo em Inglês | MEDLINE | ID: mdl-31769872

16.

Patterns of immune-cell infiltration in murine models of melanoma: roles of antigen and tissue site in creating inflamed tumors.

Leick, Katie M; Pinczewski, Joel; Mauldin, Ileana S; Young, Samuel J; Deacon, Donna H; Woods, Amber N; Bosenberg, Marcus W; Engelhard, Victor H; Slingluff, Craig L.

Cancer Immunol Immunother; 68(7): 1121-1132, 2019 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-31134297

17.

Immune Cell and Cell Cluster Phenotyping, Quantitation, and Visualization Using In Silico Multiplexed Images and Tissue Cytometry.

Blenman, Kim R M; Bosenberg, Marcus W.

Cytometry A; 2018 Nov 23.

Artigo em Inglês | MEDLINE | ID: mdl-30468565

18.

A Computational Approach for Identifying Synergistic Drug Combinations.

Gayvert, Kaitlyn M; Aly, Omar; Platt, James; Bosenberg, Marcus W; Stern, David F; Elemento, Olivier.

PLoS Comput Biol; 13(1): e1005308, 2017 01.

Artigo em Inglês | MEDLINE | ID: mdl-28085880

19.

An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background.

Mitra, Devarati; Luo, Xi; Morgan, Ann; Wang, Jin; Hoang, Mai P; Lo, Jennifer; Guerrero, Candace R; Lennerz, Jochen K; Mihm, Martin C; Wargo, Jennifer A; Robinson, Kathleen C; Devi, Suprabha P; Vanover, Jillian C; D'Orazio, John A; McMahon, Martin; Bosenberg, Marcus W; Haigis, Kevin M; Haber, Daniel A; Wang, Yinsheng; Fisher, David E.

Nature; 491(7424): 449-53, 2012 Nov 15.

Artigo em Inglês | MEDLINE | ID: mdl-23123854

20.

BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model.

Perna, Daniele; Karreth, Florian A; Rust, Alistair G; Perez-Mancera, Pedro A; Rashid, Mamunur; Iorio, Francesco; Alifrangis, Constantine; Arends, Mark J; Bosenberg, Marcus W; Bollag, Gideon; Tuveson, David A; Adams, David J.

Proc Natl Acad Sci U S A; 112(6): E536-45, 2015 Feb 10.

Artigo em Inglês | MEDLINE | ID: mdl-25624498

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Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence.

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses.

The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression.

Coordinated activation of Wnt in epithelial and melanocyte stem cells initiates pigmented hair regeneration.

PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion.

Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.

Lineage-specific transcriptional regulation of DICER by MITF in melanocytes.

Autophagy maintains tumour growth through circulating arginine.

Author Correction: Autophagy maintains tumour growth through circulating arginine.

sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance.

Therapy-induced tumour secretomes promote resistance and tumour progression.

PSGL-1 Is an Immune Checkpoint Regulator that Promotes T Cell Exhaustion.

scFTD-seq: freeze-thaw lysis based, portable approach toward highly distributed single-cell 3' mRNA profiling.

Stem cell-released oncolytic herpes simplex virus has therapeutic efficacy in brain metastatic melanomas.

PLEKHA5 regulates tumor growth in metastatic melanoma.

Patterns of immune-cell infiltration in murine models of melanoma: roles of antigen and tissue site in creating inflamed tumors.

Immune Cell and Cell Cluster Phenotyping, Quantitation, and Visualization Using In Silico Multiplexed Images and Tissue Cytometry.

A Computational Approach for Identifying Synergistic Drug Combinations.

An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background.

BRAF inhibitor resistance mediated by the AKT pathway in an oncogenic BRAF mouse melanoma model.