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Nonavalentní HPV vakcína - nová generace ockování proti HPV. / [Nine-valent HPV vaccine - new generation of HPV vaccine].

Fait, T; Dvorák, V; Pilka, R.
Ceska Gynekol; 80(6): 397-400, 2015 Dec.
Artigo em Tcheco | MEDLINE | 2015 | ID: mdl-26741152
Resumo: OBJECTIVE: To evaluate current knowledge about new generation of HPV vaccine - nine-valent vaccine Gardasil9. DESIGN: Review article. RESULTS: The nine-valent vaccine against HPV 6/11/16/18/31/33/45/52/58 could improve efficacy of quadrivalent vaccine from 70 to 90 percent for cervical cancer. In addition this vaccine has covered around85-90% of HPV-related vulvar, vaginal and anal cancers. Efficacy and immunogenicity against HPV 6/11/16/18 is the same as for quadrivalent vaccine. Efficacy against HPV 31/33/45/52/58 associated lesions is 97%.