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Recognizing diversity in parietal epithelial cells.

D'Agati, Vivette D; Shankland, Stuart J.
Kidney Int; 96(1): 16-19, 2019 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-31229027
Parietal epithelial cells comprise a heterogeneous cell population lining Bowman's capsule. The study by Kuppe et al. focused on the peritubular region of Bowman's capsule and explored the cell biology of 2 poorly characterized subtypes-the intermediate and the cuboidal parietal epithelial cells. The early and exuberant proliferative response of these subgroups in murine focal segmental glomerulosclerosis (FSGS) and human glomerular tip lesions identified a novel hot spot for glomerular lesion formation.
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