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Use of the probability of stone formation (PSF) score to assess stone forming risk and treatment response in a cohort of Brazilian stone formers.

Turney, Benjamin; Robertson, William; Wiseman, Oliver; Amaro, Carmen Regina P R; Leitão, Victor A; Silva, Isabela Leme da; Amaro, João Luiz.
Int Braz J Urol; 40(4): 507-12, 2014 Jul-Aug.
Artigo em Inglês | MEDLINE | ID: mdl-25251955

INTRODUCTION:

The aim was to confirm that PSF (probability of stone formation) changed appropriately following medical therapy on recurrent stone formers.

MATERIALS AND METHODS:

Data were collected on 26 Brazilian stone-formers. A baseline 24-hour urine collection was performed prior to treatment. Details of the medical treatment initiated for stone-disease were recorded. A PSF calculation was performed on the 24 hour urine sample using the 7 urinary parameters required: voided volume, oxalate, calcium, urate, pH, citrate and magnesium. A repeat 24-hour urine sample was performed for PSF calculation after treatment. Comparison was made between the PSF scores before and during treatment.

RESULTS:

At baseline, 20 of the 26 patients (77%) had a high PSF score (> 0.5). Of the 26 patients, 17 (65%) showed an overall reduction in their PSF profiles with a medical treatment regimen. Eleven patients (42%) changed from a high risk (PSF > 0.5) to a low risk (PSF < 0.5) and 6 patients reduced their risk score but did not change risk category. Six (23%) patients remained in a high risk category (> 0.5) during both assessments.

CONCLUSIONS:

The PSF score reduced following medical treatment in the majority of patients in this cohort.
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