Differentiation of germinal center B cells into plasma cells is initiated by high-affinity antigen and completed by Tfh cells.
Kräutler, Nike J; Suan, Dan; Butt, Danyal; Bourne, Katherine; Hermes, Jana R; Chan, Tyani D; Sundling, Christopher; Kaplan, Warren; Schofield, Peter; Jackson, Jennifer; Basten, Antony; Christ, Daniel; Brink, Robert.
J Exp Med
; 214(5): 1259-1267, 2017 05 01.
Artigo em Inglês | MEDLINE | ID: mdl-28363897
Loss of miR-182 affects B-cell extrafollicular antibody response.
T follicular helper cells, interleukin-21 and systemic lupus erythematosus.
Cognate interactions: extrafollicular IL-4 drives germinal-center reactions, a new role for an old cytokine.
Antigen Acquisition Enables Newly Arriving B Cells To Enter Ongoing Immunization-Induced Germinal Centers.
Transcription factors of the alternative NF-κB pathway are required for germinal center B-cell development.
YY1 plays an essential role at all stages of B-cell differentiation.
The 1-1-1 fallacy.
Autonomous membrane IgE signaling prevents IgE-memory formation.
B cell memory and the long-lived plasma cell.
Regulation of germinal center B-cell differentiation.