Autonomous Generation and Loading of DNA Guides by Bacterial Argonaute.
Swarts, Daan C; Szczepaniak, Malwina; Sheng, Gang; Chandradoss, Stanley D; Zhu, Yifan; Timmers, Elizabeth M; Zhang, Yong; Zhao, Hongtu; Lou, Jizhong; Wang, Yanli; Joo, Chirlmin; van der Oost, John.
; 65(6): 985-998.e6, 2017 Mar 16.
Artigo em Inglês | MEDLINE | ID: mdl-28262506
A Dynamic Search Process Underlies MicroRNA Targeting.
The structure of human argonaute-2 in complex with miR-20a.
Structure/cleavage-based insights into helical perturbations at bulge sites within T. thermophilus Argonaute silencing complexes.
A bacterial Argonaute with noncanonical guide RNA specificity.
Conformational Dynamics of Ago-Mediated Silencing Processes.
Single-Molecule Imaging Reveals that Argonaute Reshapes the Binding Properties of Its Nucleic Acid Guides.
Programmable RNA recognition using a CRISPR-associated Argonaute.
Helix-7 in Argonaute2 shapes the microRNA seed region for rapid target recognition.
piRNAs initiate an epigenetic memory of nonself RNA in the C. elegans germline.
Human Argonaute3 has slicer activity.