TRBP ensures efficient Dicer processing of precursor microRNA in RNA-crowded environments.
Fareh, Mohamed; Yeom, Kyu-Hyeon; Haagsma, Anna C; Chauhan, Sweeny; Heo, Inha; Joo, Chirlmin.
; 7: 13694, 2016 12 09.
Artigo em Inglês | MEDLINE | ID: mdl-27934859
Functional Anatomy of the Human Microprocessor.
Molecular Basis for the Single-Nucleotide Precision of Primary microRNA Processing.
Structure of Human DROSHA.
Phosphorylation of the human microRNA-generating complex mediates MAPK/Erk signaling.
Beyond secondary structure: primary-sequence determinants license pri-miRNA hairpins for processing.
Dual regulation of miRNA biogenesis generates target specificity in neurotrophin-induced protein synthesis.
Dicer partner proteins tune the length of mature miRNAs in flies and mammals.
Integrative regulatory mapping indicates that the RNA-binding protein HuR couples pre-mRNA processing and mRNA stability.
Molecular basis for interaction of let-7 microRNAs with Lin28.
Stress induces p38 MAPK-mediated phosphorylation and inhibition of Drosha-dependent cell survival.